Assessing Frontal Lobe Behavioral Syndromes with the Frontal Lobe Personality Scale

Grace, Janet; Stout, Julie C.; Malloy, Paul F.

doi:10.1177/107319119900600307

Cited by 278 publications

(174 citation statements)

References 19 publications

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“…Two of the 19 patients had disease durations of Ͼ10 years and were receiving artificial respiratory support (home mechanical noninvasive ventilation; mean duration, 68 months). We administered the Frontal Systems Behavior Scale to our patients and their caregivers, 26 a questionnaire that measures executive dysfunction; in patients with ALS, we found a frontal behavioral impairment (Table).…”

Section: Patients and Controlsmentioning

confidence: 99%

Widespread Microstructural White Matter Involvement in Amyotrophic Lateral Sclerosis: A Whole-Brain DTI Study

Cirillo¹,

Esposito²,

Tedeschi³

et al. 2012

AJNR Am J Neuroradiol

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BACKGROUND AND PURPOSE:The extensive application of advanced MR imaging techniques to the study of ALS has undoubtedly improved our knowledge of disease pathophysiology, even if the actual spread of the neurodegenerative process throughout the central nervous system is not fully understood. The present study aimed to detect WM patterns of microstructural abnormalities to better investigate the pathologic process in ALS, within but also beyond CSTs, in a whole-brain analysis.

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Section: Patients and Controlsmentioning

confidence: 99%

Widespread Microstructural White Matter Involvement in Amyotrophic Lateral Sclerosis: A Whole-Brain DTI Study

Cirillo¹,

Esposito²,

Tedeschi³

et al. 2012

AJNR Am J Neuroradiol

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“…Escala de Comportamiento del Sistema Frontal (FrSBe; Grace et al,, 1999;Grace y Malloy, 2001): es una escala de 46 ítems, dividida en 3 subescalas derivadas del análisis factorial: Apatía (FRSBEa), Desinhibición (FRSBEd) y Disfunción Ejecutiva (FRSBEe), y proporciona también una puntuación global (FRSBEt). Las respuestas se efectúan en una escala tipo Likert, de acuerdo con el instrumento original.…”

Section: Instrumentosunclassified

Versión española del Cuestionario Disejecutivo (DEX-Sp): propiedades psicométricas en adictos y población no clínica

Pérez¹,

León

Mota

et al. 2009

Adicciones

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Objective: Several studies have shown evidence of executive function impairment associated with substance abuse. This suggests the potential usefulness of a baseline assessment measure to screen for dysexecutive impairments in individuals beginning treatment. The Dysexecutive Questionnaire (DEX) is a test widely used to estimate executive dysfunction. The main objective of this work is to study the psychometric properties of the Spanish version of the Dysexecutive Questionnaire (DEX-Sp). A complementary goal is to study its potential utility for initial screening in addicted individuals seeking treatment. Method: A sample of 131 non-clinical and 127 clinical individuals meeting the DSM-IV-TR substance abuse or dependence criteria were recruited. Results: Internal consistency of the questionnaire was assessed (Cronbach's α =0.91), as well as other reliability indicators. Exploratory and confirmatory factor analysis offers four-and five-factor solutions. Also tested were the dimensionality and structural model and its convergent and discriminant validity with other instruments. Differences between clinical and non-clinical individuals and total scores were also analyzed. Conclusions: The data suggest that the Spanish version of the DEX is a useful measure for assessing general symptoms of dysexecutive syndrome, and a valid, reliable and adequate screening test for estimating cognitive impairment associated with substance abuse.Key words: Executive functions, dysexecutive syndrome, frontal lobe, addictive behaviour, questionnaires, psychometrics, factor analysis, treatment. RESUMEN ABSTRACTObjetivo: Diversos estudios han evidenciado el deterioro de las funciones ejecutivas asociado al abuso de sustancias. Este hecho sugiere la conveniencia de contar con algún instrumento de cribado que sirva para establecer una línea base sobre los déficits que presentan los sujetos que inician tratamiento. El Cuestionario Disejecutivo (DEX) es un test ampliamente utilizado para estimar disfunción ejecutiva. El principal objetivo del presente trabajo se centra en estudiar las propiedades de la versión española del Cuestionario Disejecutivo (DEX-Sp). Complementariamente se pretende estudiar su potencial utilidad como instrumento de cribado en adictos en tratamiento. Método: 131 sujetos de población no clínica y 127 adictos (con criterios DSM-IV-TR para abuso o dependencia). Resultados: Se estudia la consistencia interna (α de Cronbach = 0,91) entre otros indicadores de fiabilidad. El análisis factorial exploratorio y confirmatorio ofrece soluciones de 4 y 5 factores. Se estudió la dimensionalidad y el modelo estructural de base, así como la validez convergente y discriminante. Se estudiaron las diferencias apreciadas entre adictos y población no clínica. Conclusiones: Los datos sugieren que la versión española del DEX es un instrumento útil para evaluar síntomas disejecutivos generales, con la suficiente fiabilidad y validez para explorar deterioro cognitivo asociado al abuso de sustancias.

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“…The quantitative assessment of clinical UMN involvement was based on a scale used in previous ALS neuroimaging studies, 35 a questionnaire that measures apathy, disinhibition, and executive dysfunction and quantifies changes with time by comparing baseline (retrospective) and current assessments of behavior in a standardized T score (T Ͼ 65 is defined as impaired behavior and executive functions), was also administered to our patients and their caregivers. In our population, the mean total T score was 110.8 Ϯ 21.7, derived from the caregiver and referring to the present time; the T score was Ͼ 65 in 19 of 20 patients.…”

Section: Study Populationmentioning

confidence: 99%

Frontotemporal Cortical Thinning in Amyotrophic Lateral Sclerosis

d’Ambrosio

Gallo

Trojsi

et al. 2013

American Journal of Neuroradiology

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BACKGROUND AND PURPOSE:The extensive application of advanced MR imaging techniques has undoubtedly improved our knowledge of the pathophysiology of amyotrophic lateral sclerosis. Nevertheless, the precise extent of neurodegeneration throughout the central nervous system is not fully understood. In the present study, we assessed the spatial distribution of cortical damage in amyotrophic lateral sclerosis by using a cortical thickness measurement approach.

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Assessing Frontal Lobe Behavioral Syndromes with the Frontal Lobe Personality Scale

Cited by 278 publications

References 19 publications

Widespread Microstructural White Matter Involvement in Amyotrophic Lateral Sclerosis: A Whole-Brain DTI Study

Widespread Microstructural White Matter Involvement in Amyotrophic Lateral Sclerosis: A Whole-Brain DTI Study

Versión española del Cuestionario Disejecutivo (DEX-Sp): propiedades psicométricas en adictos y población no clínica

Frontotemporal Cortical Thinning in Amyotrophic Lateral Sclerosis

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