2007
DOI: 10.1111/j.1460-9592.2007.02265.x
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Aspects of bleeding after cardiac surgery in children

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Cited by 43 publications
(27 citation statements)
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“…Second, the CPB circuit requires priming with a mixture of allogenic blood and/or crystalloid solutions, e.g., normal saline, which causes a significant hemodilution of clotting factors and platelets. A resulting variable dysfunction of hemostasis is seen in all pediatric patients (4,5).…”
mentioning
confidence: 99%
“…Second, the CPB circuit requires priming with a mixture of allogenic blood and/or crystalloid solutions, e.g., normal saline, which causes a significant hemodilution of clotting factors and platelets. A resulting variable dysfunction of hemostasis is seen in all pediatric patients (4,5).…”
mentioning
confidence: 99%
“…Hemodilution, and the consequent decrease in platelets and coagulation factor, is the most important mechanism for the development of coagulopathy in this clinical situation, due to the large discrepancy in the child's blood volume and the priming volume of the bypass circuit (11) . Following surgical correction of CHD requiring ECMO, bleeding occurs in 63% of pediatric patients (11) mainly due to the need for surface heparinization of the system (12) . Bleeding precautions (Code 4010) is a NIC defined as "reduction of stimuli that may induce bleeding or hemorrhage in at-risk patients" (2) .…”
Section: Discussionmentioning
confidence: 99%
“…The surgical procedure and ECMO are both strongly related to bleeding in children. Neonates and small infants are the highest risk group for excessive bleeding after cardiac surgery (11) . Hemodilution, and the consequent decrease in platelets and coagulation factor, is the most important mechanism for the development of coagulopathy in this clinical situation, due to the large discrepancy in the child's blood volume and the priming volume of the bypass circuit (11) .…”
Section: Discussionmentioning
confidence: 99%
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