Aspectos analíticos del analizador de gases Cobas® b 221 (Roche Diagnostics)

Ameijeiras, Fernando Jesús Hermida; Ponce, Berta González; Noreña, Blanca Reimunde

doi:10.1016/j.labcli.2010.05.001

Cited by 2 publications

(1 citation statement)

References 19 publications

(7 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The parameters examined in this study were total protein, direct bilirubin, Alanine aminotransaminase (ALT), Aspartate aminotransaminase (AST), Alkaline Phosphatase (ALP), Urea, Creatinine, and Uric Acid using Cobas 6000 (Roche diagnostic, Switzerland). The measurement of sodium, chloride, and potassium levels was done using Cobas b 221 (Roche diagnostic, Switzerland) ( Van et al 2008;Ameijeiras et al 2010).…”

Section: Biochemical Analysismentioning

confidence: 99%

Oral acute toxicity study extract ethanol of balakka fruit (Phyllanthus emblica)

Anto¹,

Syahputra²,

Silitonga³

et al. 2022

PHAR

View full text Add to dashboard Cite

Phyllanthus emblica (PE) is a plant widely found in Indonesia, especially in Sumatra island, and in India. This study followed the OECD No. 420. The groups were divided based on gender, male and female rats. Male rats were divided into 6 groups, which were male/female control, male/female 2000 mg/kgBW, and male/female 5000 mg/kgBW. This study revealed that the ethanol extract of Phyllanthus emblica (EEPE) doses of 2000 mg/kgBW and 5000 mg/kgBW did not cause histological changes in the heart, liver, testes, ovaries, and kidneys, and did not cause changes to the hematological parameters, kidney biochemical parameters, liver biochemical parameters, and electrolyte parameters both in male and female rats. The results show that the LD50 of EEPE is higher than 5000 mg/kgBW. In short, this study provides information regarding the antioxidant activity and the safe use of EEPE. The LD50 of extract ethanol of Phyllanthus emblica is higher than 5000 mg/kgBW.

show abstract

Section: Biochemical Analysismentioning

confidence: 99%

Oral acute toxicity study extract ethanol of balakka fruit (Phyllanthus emblica)

Anto¹,

Syahputra²,

Silitonga³

et al. 2022

PHAR

View full text Add to dashboard Cite

show abstract

Acute toxicity test nanoherbal mahkota dewa fruit (Phaleria macrocarpa)

Simanjuntak¹,

Rumahorbo²

2022

PHAR

View full text Add to dashboard Cite

A common plant from Papua, Indonesia, called Phaleria macrocarpa (mahkota dewa), has potent therapeutic components. The aim of this study was to evaluate the toxicity level of nanoherbal mahkota dewa and its effect on the changes in hematology, biochemistry, electrolytes, and histopathology of the organ. High Energy Milling (HEM) was used to produce nanoherbal mahkota dewa. LD50 was determined in three stages: dose orientation test (12 mice), preliminary test (20 mice), and LD50 determination (30 mice) for 14 days using the Thomson Weil formula. LC50 was determined using the Brine Shrimp Lethality Test method with concentrations of 1, 10, 100, 1000, and 10,000 ppm. This study revealed that the LD50 value was 1g/kg BW 0,075 and the LC50 value was 2145,0407 ppm. The nanoherbal mahkota dewa affected the histological organs, hematological, biochemical, and electrolyte parameters but did not affect the weight of the organ significantly. From this study, it can be concluded that nanoherbal mahkota dewa belongs to the category of moderate toxicity. In a proper dose, it could be processed as an herbal medicine in the future.

show abstract

Aspectos analíticos del analizador de gases Cobas® b 221 (Roche Diagnostics)

Cited by 2 publications

References 19 publications

Oral acute toxicity study extract ethanol of balakka fruit (Phyllanthus emblica)

Oral acute toxicity study extract ethanol of balakka fruit (Phyllanthus emblica)

Acute toxicity test nanoherbal mahkota dewa fruit (Phaleria macrocarpa)

Contact Info

Product

Resources

About

Aspectos analíticos del analizador de gases Cobas® b 221 (Roche Diagnostics)

Cited by 2 publications

References 19 publications

﻿Oral acute toxicity study extract ethanol of balakka fruit (Phyllanthus emblica)

﻿Oral acute toxicity study extract ethanol of balakka fruit (Phyllanthus emblica)

﻿Acute toxicity test nanoherbal mahkota dewa fruit (Phaleria macrocarpa)

Contact Info

Product

Resources

About

Oral acute toxicity study extract ethanol of balakka fruit (Phyllanthus emblica)

Oral acute toxicity study extract ethanol of balakka fruit (Phyllanthus emblica)

Acute toxicity test nanoherbal mahkota dewa fruit (Phaleria macrocarpa)