Artificial nanozyme based on platinum nanoparticles anchored metal-organic frameworks with enhanced electrocatalytic activity for detection of telomeres activity

Ling, Pinghua; Qian, Caihua; Yu, Jinjin; Gao, Feng

doi:10.1016/j.bios.2019.111838

Cited by 61 publications

(16 citation statements)

References 56 publications

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“…[301], d Ref. [302], e Ref. [303] with permission functionalizing AuNPs with oligo-ethylene glycol (OEG) [293].…”

Section: Heavy Metal Ionsmentioning

confidence: 99%

“…Thence, metal- and metal oxide-based nanozymes functioned as signal amplification has boosted biomarkers analysis in sundry assays involving electrochemical, fluorescent and so on [ 300 ]. Ling et al obtained Pt@ P-MOF (Fe) nanozymes by growing ultra-small Pt nanoparticles on metalloporphyrin metal organic frameworks [ 302 ]. The novel artificial nanozymes were employed as signal probe, allosteric switch of DNA and Exo III recycling amplification in their electrochemical template for telomerase detection (Fig.…”

Section: Applications Of Metal- and Metal Oxide-based Nanozymesmentioning

confidence: 99%

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A Review on Metal- and Metal Oxide-Based Nanozymes: Properties, Mechanisms, and Applications

et al. 2021

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Since the ferromagnetic (Fe3O4) nanoparticles were firstly reported to exert enzyme-like activity in 2007, extensive research progress in nanozymes has been made with deep investigation of diverse nanozymes and rapid development of related nanotechnologies. As promising alternatives for natural enzymes, nanozymes have broadened the way toward clinical medicine, food safety, environmental monitoring, and chemical production. The past decade has witnessed the rapid development of metal- and metal oxide-based nanozymes owing to their remarkable physicochemical properties in parallel with low cost, high stability, and easy storage. It is widely known that the deep study of catalytic activities and mechanism sheds significant influence on the applications of nanozymes. This review digs into the characteristics and intrinsic properties of metal- and metal oxide-based nanozymes, especially emphasizing their catalytic mechanism and recent applications in biological analysis, relieving inflammation, antibacterial, and cancer therapy. We also conclude the present challenges and provide insights into the future research of nanozymes constituted of metal and metal oxide nanomaterials.

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“…[301], d Ref. [302], e Ref. [303] with permission functionalizing AuNPs with oligo-ethylene glycol (OEG) [293].…”

Section: Heavy Metal Ionsmentioning

confidence: 99%

Section: Applications Of Metal- and Metal Oxide-based Nanozymesmentioning

confidence: 99%

A Review on Metal- and Metal Oxide-Based Nanozymes: Properties, Mechanisms, and Applications

et al. 2021

View full text Add to dashboard Cite

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“…In comparison to common inorganic porous materials, the properties of MOF can be naturally and easily modified to prevent damage to guest molecules caused by complicated procedures. The heterostructures formed using MOFs with NPs or nanocarbon-based materials further compensates for some of the inherent defects of MOFs ( Ling et al, 2020 ).…”

Section: Synthesis and Modification Of Mofs For Electroactive Materialsmentioning

confidence: 99%

Recent Advances in Metal-Organic Framework-Based Electrochemical Biosensing Applications

Li¹,

Zhang²,

Boakye³

et al. 2021

Front. Bioeng. Biotechnol.

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In the face of complex environments, considerable effort has been made to accomplish sensitive, accurate and highly-effective detection of target analytes. Given the versatility of metal clusters and ligands, high porosity and large specific surface area, metal–organic framework (MOF) provides researchers with prospective solutions for the construction of biosensing platforms. Combined with the benefits of electrochemistry method such as fast response, low cost and simple operation, the untapped applications of MOF for biosensors are worthy to be exploited. Therefore, this review briefly summarizes the preparation methods of electroactive MOF, including synthesize with electroactive ligands/metal ions, functionalization of MOF with biomolecules and modification for MOF composites. Moreover, recent biosensing applications are highlighted in terms of small biomolecules, biomacromolecules, and pathogenic cells. We conclude with a discussion of future challenges and prospects in the field. It aims to offer researchers inspiration to address the issues appropriately in further investigations.

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“…The raw materials affect the properties of nanozymes in different ways, including chemical composition (such as, metal-based or non-metal-based), synthetic methods (such as, dipping, co-precipitation, deposition-precipitation, hydrothermal/ solvothermal), exist forms (such as, spherical, rod-shaped, ring-shaped, hollow structure). [31] The nanomaterials of magnetic iron oxides nanoparticles, [32] platinum nanoparticles, [33] manganese oxides nanoparticles, [34] gold nanoparticles, [35] and vanadium pentoxide nanowires [3] have been investigated to mimics natural enzymes to anti-oxidation. Although they exhibit excellent enzyme catalytic activities, their enzymatic properties are different.…”

Section: Different Enzymatic Activitiesmentioning

confidence: 99%

Recent Advances in Nanozymes: From Matters to Bioapplications

Liang

et al. 2021

Adv Funct Materials

207

115

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The manufacture of bionic materials to simulate the natural counterparts has attracted extensive attention. As one of the subcategories of biomimetic materials, the development of artificial enzyme is intensive pursuing. As a kind of artificial enzyme, nanozymes are dedicated to solve the limitations of natural enzymes. In recent years, attributed to the explosive development of nanotechnology, biotechnology, catalysis science, computational design and theory calculation, research on nanozymes has made great progress. To highlight these achievements and help researchers to understand the current investigation status of nanozyme, the state‐of‐the‐art development in nanozymes from fabrication materials to bioapplications are summarized. First different raw materials are summarized, including metal‐based, metal‐free, metal‐organic frameworks‐based, and some other novel matters, which are applied to fabricate nanozymes. The different types of enzymes‐like catalytic activities of nanozymes are briefly discussed. Subsequently, the wide applications of nanozymes such as anti‐oxidation, curing diseases, anti‐bacteria, biosensing, and bioimaging are discussed. Finally, the current challenges faced by nanozymes are outlined and the future directions for advancing nanozyme research are outlooked. The authors hope this review can inspire research in the fields of nanotechnology, chemistry, biology, materials science, and theoretical computing, and can contribute to the development of nanozymes.

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Artificial nanozyme based on platinum nanoparticles anchored metal-organic frameworks with enhanced electrocatalytic activity for detection of telomeres activity

Cited by 61 publications

References 56 publications

A Review on Metal- and Metal Oxide-Based Nanozymes: Properties, Mechanisms, and Applications

A Review on Metal- and Metal Oxide-Based Nanozymes: Properties, Mechanisms, and Applications

Recent Advances in Metal-Organic Framework-Based Electrochemical Biosensing Applications

Recent Advances in Nanozymes: From Matters to Bioapplications

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