Arterial stiffness: beyond pulse wave velocity and its measurement

Lim, Hoong Sern; Lip, Gregory Y.H.

doi:10.1038/jhh.2008.47

Cited by 36 publications

(19 citation statements)

References 23 publications

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“…Although the precise nature of the relation between coffee and BP is still unclear, most evidence suggests that regular intake of caffeinated coffee does not increase the risk of hypertension. 16 AS and wave reflection can indicate different aspects of vascular status in otherwise healthy subjects 32 and in hypertensive patients 25 ; atherosclerosis is a process that does not affect the arterial bed uniformly but has a variable local distribution and is frequently superimposed on stiffened vessels. 33 It is known that lifestyle interventions, such as those achieving modest weight loss and even only physical exercise without weight changes, are associated AS changes and with improvements in insulin sensitivity and lipid profile 34,35 : impaired insulin sensitivity may be involved in the development of renal dysfunction at an early stage, before the onset of diabetes or prediabetic glucose elevations.…”

Section: Discussionmentioning

confidence: 99%

Coffee, nutritional status, and renal artery resistive index

et al. 2010

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Background: The relationship between nutrition and atherosclerosis is known, even dissociated from protein malnutrition. Cardiovascular impact of several nutrients is known; among them the action of coffee is still debated and cardiovascular effect of caffeine has been investigated without definite results. Objective: The aim of this study is to investigate whether coffee habits, and/or quantity of coffee consumption, have any relationship with renal resistive index (RRI), a hallmark of arterial stiffness (AS). The relationship of AS with nutritional status assessed by body composition and serum albumin, insulin resistance (assessed by HOMA), and renal function assessed by glomerular filtration rate (GFR) is concurrently investigated. Methods: This study was done with 221 consecutive patients, without diabetes, cancer, liver, renal, and heart disease, referred for clinical noninvasive assessment and nutritional counseling: 124 essential hypertensive and 97 nonhypertensive patients were eligible. Personalized Mediterranean diet, physical activity increase, and smoking withdrawal counseling were provided. Results: By multiple linear regression, fat-free mass (FFM), HOMA (positive relationship), and number of cups of coffee/day (negative relationship) account for 17.2% of the variance to RRI. By odds ratios lower risk to increased RRI is associated with higher serum albumin, higher hemoglobin, and FFM; greater risk is associated with hypertension, insulin resistance (HOMA ≥ 3.0), and renal insufficiency (GFR ≤ 90); coffee, assessed by number of cups/day, reduces risk. Conclusion: Coffee use is inversely associated with RRI. Habitual coffee users have risk protection to higher RRI; lower serum albumin, insulin resistance, and renal insufficiency are associated with greater RRI.

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Section: Discussionmentioning

confidence: 99%

Coffee, nutritional status, and renal artery resistive index

et al. 2010

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“…Second, the sample of Cuban Americans may not be representative of Cuban Americans living in Florida or the United States. Third, although PP has been considered a risk factor for arterial stiffness, we did not use pulse wave pressure, which has been considered the gold standard [41]. Finally, the source of fructose was not determined.…”

Section: Discussionmentioning

confidence: 99%

The Effect of Carbohydrate Amount, Quality and Type on Arterial Pulse Pressure in Cuban-Americans with and Without Type 2 Diabetes

et al. 2011

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Background: Arterial pulse pressure, the difference between systolic and diastolic blood pressure, has been used as an indicator (surrogate measure) of arterial stiffness. High arterial pulse pressure (> 40) has been associated with increased cardiovascular disease and mortality. Several clinical trials have reported that the proportion of calories from carbohydrate has an effect on blood pressure. The primary objective of this study was to assess arterial pulse pressure and its association with carbohydrate quantity and quality (glycemic load) with diabetes status for a Cuban American population.

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“…In particular, the brachial-ankle pulse wave velocity (BaPWV) in the assessment of cardiovascular risk factors is often used to predict early cardiovascular disease, and it is used as a clinical indicator12, 13 ) . Higher BaPWV correlates with a stiffer arterial wall and greater cardiovascular risk factors14 ) . In contrast, decreased BaPWV can be related to a decrease in vessel stiffness15 ) .…”

Section: Introductionmentioning

confidence: 99%

Waveform Analysis of the Brachial-ankle Pulse Wave Velocity in Hemiplegic Stroke Patients and Healthy Volunteers: A Pilot Study

Kim

Lee

et al. 2014

J Phys Ther Sci

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[Purpose] Brachial-ankle pulse wave velocity (BaPWV), which has been reported as an index of arterial stiffness, is very closely related to cardiovascular risk factors. A high BaPWV indicates high cardiovascular risk. However, BaPWV and pressure waveforms after stroke are not fully understood. [Methods] BaPWV was measured in thirty-two subjects (twenty-two healthy volunteers and ten stroke patients) while they were in the supine position. It was measured in their bilateral upper and lower extremities. [Results] BaPWV was significantly increased in the stroke group compared with the healthy volunteers. It was also significantly increased on both the affected and non-affected sides of stroke patients in the stroke group. Furthermore, analysis of the pressure waveforms showed that the peak pressure was significantly increased in the stroke group compared with the control group. The peak pressure on both the affected and non-affected sides was also significantly greater than in the control group. However, the rise and decay times were significantly decreased in the stroke group compared with the control group. The rise and decay time on both the affected and non-affected sides were also significantly more decreased than in the control group. [Conclusion] The results demonstrated that increased BaPWV and changed pulse waves are closely associated with the pathologic states of hemiplegic stroke patients.

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Arterial stiffness: beyond pulse wave velocity and its measurement

Cited by 36 publications

References 23 publications

Coffee, nutritional status, and renal artery resistive index

Coffee, nutritional status, and renal artery resistive index

The Effect of Carbohydrate Amount, Quality and Type on Arterial Pulse Pressure in Cuban-Americans with and Without Type 2 Diabetes

Waveform Analysis of the Brachial-ankle Pulse Wave Velocity in Hemiplegic Stroke Patients and Healthy Volunteers: A Pilot Study

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