Are women privileged organ recipients?

Inoue, Sumio; Yamada, Yasunari; Kuzuhara, K; Ubara, Y; Ootubo, O

doi:10.1016/s0041-1345(02)03408-5

Cited by 9 publications

(13 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Among those, six studies compared the measurements from results involving donor genders (MD and FD); eight studies, involving recipient genders (MR and FR), and for 20 others, results involving donor-recipient genders (MD-MR, MD-FR, FD-FR, FD-MR) ( Figure ). One study was included in donor, recipient, and donor-recipient gender comparisons; 5 another one 14 was included in the comparison between recipient and donor-recipient genders; and two studies, in the comparison between donor and donor-recipient genders. 3 , 25…”

Section: Resultsmentioning

confidence: 99%

Gender in the allocation of organs in kidney transplants: meta-analysis

et al. 2015

View full text Add to dashboard Cite

OBJECTIVE To analyze whether gender influence survival results of kidney transplant grafts and patients.METHODS Systematic review with meta-analysis of cohort studies available on Medline (PubMed), LILACS, CENTRAL, and Embase databases, including manual searching and in the grey literature. The selection of studies and the collection of data were conducted twice by independent reviewers, and disagreements were settled by a third reviewer. Graft and patient survival rates were evaluated as effectiveness measurements. Meta-analysis was conducted with the Review Manager® 5.2 software, through the application of a random effects model. Recipient, donor, and donor-recipient gender comparisons were evaluated.RESULTS : Twenty-nine studies involving 765,753 patients were included. Regarding graft survival, those from male donors were observed to have longer survival rates as compared to the ones from female donors, only regarding a 10-year follow-up period. Comparison between recipient genders was not found to have significant differences on any evaluated follow-up periods. In the evaluation between donor-recipient genders, male donor-male recipient transplants were favored in a statistically significant way. No statistically significant differences were observed in regards to patient survival for gender comparisons in all follow-up periods evaluated.CONCLUSIONS The quantitative analysis of the studies suggests that donor or recipient genders, when evaluated isolatedly, do not influence patient or graft survival rates. However, the combination between donor-recipient genders may be a determining factor for graft survival.

show abstract

Section: Resultsmentioning

confidence: 99%

Gender in the allocation of organs in kidney transplants: meta-analysis

et al. 2015

View full text Add to dashboard Cite

show abstract

“…After review of the abstract, 904 were excluded and later a further 17 were excluded by review of the full text. The remaining 14 studies met the inclusion criteria . The included studies enrolled a total of 445 279 patients who underwent kidney transplantation.…”

Section: Resultsmentioning

confidence: 99%

The effect of donor‐recipient gender mismatch on short‐ and long‐term graft survival in kidney transplantation: a systematic review and meta‐analysis

Zhou

Cheng

Huang

et al. 2013

Clinical Transplantation

View full text Add to dashboard Cite

show abstract

“…The phenomenon of a gender advantage in transplants has been observed in several solid organ scenarios. Female kidney transplant recipients have a higher (by 8%) cumulative survival rate and a lower (by 75%) incidence of severe graft rejection, as compared to male recipients . In female recipients of a heart transplant or a lung transplant, a survival advantage over male recipients has been noted (although that advantage is largely accounted for by the negative influence of female‐to‐male mismatches) .…”

Section: Discussionmentioning

confidence: 99%

“…Female kidney transplant recipients have a higher (by 8%) cumulative survival rate and a lower (by 75%) incidence of severe graft rejection, as compared to male recipients. 13 In female recipients of a heart transplant or a lung transplant, a survival advantage over male recipients has been noted (although that advantage is largely accounted for by the negative influence of female-to-male mismatches). 14,15 In the field of lung transplantation, several, but not all, authors have observed a survival advantage for female recipients.…”

Section: Gender Effects On Bronchiolitis Obliteransfree Survivalmentioning

confidence: 99%

Gender differences in long‐term survival post‐transplant: A single‐institution analysis in the lung allocation score era

Loor

Brown

Kelly

et al. 2017

Clinical Transplantation

View full text Add to dashboard Cite

Purpose To clarify the significance of recipient gender status on lung transplant outcomes in a large single institution experience spanning three decades. Methods We analyzed data from all lung transplants performed in our institution since 1986. Kaplan-Meier curves and Cox proportional hazard models were used to evaluate the effect of recipient characteristics on survival and BOS score ≥1-free survival. Logistic regression analysis was used to explore the association of gender with short term graft function. Results 876 lung transplants were performed between 1986 and 2016. Kaplan-Meier survival estimates at 5 years post-transplant for females versus males in the LAS era were 71% versus 58%. In the LAS era females showed greater unadjusted BOS ≥ 1-free survival than males (35% vs 25%, P=0.02] over 5 years. Female gender was the only factor in the LAS era significantly associated with improved adjusted 5 year survival [HR 0.56 (95% CI 0.33, 0.95) P=0.03]. Conversely, in the pre-LAS era female gender was not associated with improved survival. Conclusion Female recipients showed significantly improved survival over 5 years compared to males in the LAS era. A prospective analysis of biologic and immunologic differences is warranted.

show abstract

Are women privileged organ recipients?

Cited by 9 publications

References 5 publications

Gender in the allocation of organs in kidney transplants: meta-analysis

Gender in the allocation of organs in kidney transplants: meta-analysis

The effect of donor‐recipient gender mismatch on short‐ and long‐term graft survival in kidney transplantation: a systematic review and meta‐analysis

Gender differences in long‐term survival post‐transplant: A single‐institution analysis in the lung allocation score era

Contact Info

Product

Resources

About