Are all types of food safe with prescribed medicines? A study of potential food-drug interactions in patients attending Medicine OPD

Chavda, Nilesh; Dhanani, Jatin V; Solanky, Priti; Tandel, Kirtida R; Patel, Nirav

doi:10.5455/ijmsph.2016.28102015237

Cited by 3 publications

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“…The potential risk for DFIs have been determined in different countries with varying rates ranging from approximately 20-89%. 1,[8][9][10][11] Although this prevalence has not been determined in South Africa, the reported high prevalence imposes a need for careful attention, especially among susceptible patients. Elderly patients, patients taking multiple medications, those with chronic conditions such as diabetes, hypertension, or hyperlipidaemia and patients with nutritional deficiencies are at an increased risk for DFIs.…”

Section: Introductionmentioning

confidence: 99%

Knowledge, attitudes, and practices towards drug-food interactions among patients at public hospitals in eThekwini, KwaZulu-Natal, South Africa

Osuala¹,

Tlou²,

Ojewole³

2022

Afr H. Sci.

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Background: Drug-food interactions can lead to adverse drug reactions and therapy failure which can potentially impact patient safety and therapy outcome. Objectives: This study assessed patients’ knowledge, attitudes and practices regarding drug-food interactions. Methods: A cross-sectional study was conducted among patients at three public hospitals in eThekwini, KwaZulu-Natal. Statistical analysis was performed using SPSS® version 25. The association between demographic variables and patients’ knowledge, attitudes and practices were assessed. Results: Of the 342 patients, 70.5% were female, and the mean age was 42.87±0.89 years. Almost 50% of patients had secondary level education, and 64% were unemployed. About 52% of patients had high knowledge of drug-food interactions; however, only 30-50% of the patients could identify potential drug-food interactions of their drugs. More than halfof the patients (51.5%) answered that they took multivitamin pills with medications and 61.7% responded they consulted healthcare professionals for drug-food interactions’ information before taking new medications. Few patients (15.2%) had experienced drug-food interactions. Conclusions: Overall, patients had gaps in their knowledge and practices, and positive attitudes towards drug-food interactions. Many patients could not identify food items that can potentially interact with their drugs. It is important that education and medication counselling are provided to patients to prevent drug-food interactions, ensure optimal drug therapy and patient safety. Keywords: Drug-food interactions; patients; knowledge; attitudes; practices.

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Section: Introductionmentioning

confidence: 99%

Knowledge, attitudes, and practices towards drug-food interactions among patients at public hospitals in eThekwini, KwaZulu-Natal, South Africa

Osuala¹,

Tlou²,

Ojewole³

2022

Afr H. Sci.

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Drug Disposition Considerations in Pharmaceutical Product

Maheshwari

Sharma

Seth

et al. 2018

Dosage Form Design Considerations

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Knowledge, attitudes and practices of healthcare professionals regarding drug–food interactions: a scoping review

Osuala

Ojewole

2021

International Journal of Pharmacy Practice

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Objectives Drug–food interactions (DFIs) are a problem in clinical practice as they can alter the bioavailability of drugs and nutrients and may lead to various adverse effects. Healthcare professionals (HCPs) play a significant role in counselling patients and preventing these interactions. Knowledge, attitudes and practices (KAPs) regarding DFIs are, therefore, vital to ensure that they carry out their role efficiently. This review maps evidence on KAPs of HCPs regarding DFIs and highlights gaps for further research. Methods A systematic literature search for the period from 1990 to 2018 was done using Google Scholar, PubMed and ScienceDirect. Keywords such as ‘knowledge, attitudes, practices, healthcare professionals, drug-food interactions’ in combination with the Boolean operator (AND) were used. Articles published only in English that described KAPs of HCPs relating to DFIs were included. Key findings Twelve studies were included in this review. Inadequate knowledge was observed among the HCPs as they were unable to identify important DFIs. The HCPs had a positive attitude towards acquiring knowledge, reporting and counselling patients on DFIs. Most of the medical residents felt that they were inadequately trained on DFIs and over half believed that DFIs were only slightly important in clinical practice. Conclusion Deficits exist in the KAPs of HCPs regarding DFIs. An educational intervention targeting HCPs is recommended. Further research assessing the KAPs of the HCPs is required as the small number of studies conducted was a limitation.

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Are all types of food safe with prescribed medicines? A study of potential food-drug interactions in patients attending Medicine OPD

Cited by 3 publications

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Knowledge, attitudes, and practices towards drug-food interactions among patients at public hospitals in eThekwini, KwaZulu-Natal, South Africa

Knowledge, attitudes, and practices towards drug-food interactions among patients at public hospitals in eThekwini, KwaZulu-Natal, South Africa

Drug Disposition Considerations in Pharmaceutical Product

Knowledge, attitudes and practices of healthcare professionals regarding drug–food interactions: a scoping review

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