Aqueous Extracts of Seed and Peel of Carica Papaya Against Aedes Aegypti

Hayatie, Lisda; Biworo, Agung; Suhartono, Eko

doi:10.12720/jomb.4.5.417-421

Cited by 18 publications

(24 citation statements)

References 10 publications

(20 reference statements)

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“… C. papaya seeds protect fibroblasts from H2O2-induced stress due to the antioxidant activity of the water extract [32].  Also used in the treatment of hypertension, diabetes mellitus and hypercholesterolemia  The seed has been shown to be a good source of oil (25.6%) that may be useful for medicinal, bio fuel and industrial purposes [33].  The seeds are medicinally important in the treatment of sickle cell disease, poisoning related disorder [34].…”

Section: Therapautic and Medicinal Valuesmentioning

confidence: 99%

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Medicinal Uses of Carica Papaya

Basalingappa¹

2018

JONAM

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ObjectiveMedicinal plants have been used for various diseases traditionally in many countries, because of its advantages like easy availability, effective and economical in therapeutics. Carica papaya, also called as pawpaw is traditionally cultivated for fruit. Carica papaya belonging to the genus Carica. It contains the enzyme papain, chymopapain which is biologically active and has medicinal and nutritional values. All parts of the plant like leaves, fruits, seeds, flowers and roots can be used by humans as food and medicinal purposes. This plant has therapeutic uses like anti-amoebic, anti-microbial, anti fertility activity, anti-ulcerogenic, anti-fungal, antitumor, hypolipidaemic and employ in wound -healing activity, free radical scavenging activity, diuretic activity, uterotonic activity. In this review we have discussed details about papaya plant parts and its uses.

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Section: Therapautic and Medicinal Valuesmentioning

confidence: 99%

“… The phytochemical of C. papaya peel extracts can be well utilized for preparing biocides or insecticidal formulation. Peel of C. papaya might be the reason for its larvicidal activity against Aedes aegypti [33].  Papaya peel too possesses wound healing properties [34].…”

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confidence: 99%

Medicinal Uses of Carica Papaya

Basalingappa¹

2018

JONAM

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“…Namun, akhir-akhir ini 10,11 beberapa kota di Indonesia telah melaporkan adanya kasus resistensi nyamuk yang tidak mati setelah terpapar larvasida maupun insektisida, seperti di Surabaya, Tasikmalaya, dan Ambon. [12][13][14] Larvasida nabati adalah harapan dan alternatif untuk pengendalian vektor terutama larva nyamuk.…”

Section: Abstract / a B S T R A Kunclassified

Potensi Larvasida dari Ekstrak Daun Jeruk Bali Citrus maxima terhadap dan Aedes aegypti dan Culex quinquefasciatus

Ardianto¹,

Anshori²,

Hamidah³

2018

vektorp

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Abstract The used of chemical insecticides for mosquito control has caused resistance in themosquito populations. The aims of this study are to find out Lethal Concentration of non-polarextract from pomelo (Citrus maxima) leaf against mosquito larvae after 24 hoursexposure. Aedes aegypti and Culex quinquefasciatus larvae were tested in the study A.Larvicidal assay was using 20 larvae for each concentration in 100 ml solution with 5replications. The non-polar extract was tested at concentrations of 0 ppm, 500 ppm, 1375ppm, 2250 ppm, 3125 ppm, and 4000 ppm. The number of larvae mortality wasdetermined after 24 hours exposure. The dead larvae were counted and the data wasanalyzed using probit analyze. The results showed that non-polar extract from Citrusmaxima Leaf has potential larvicidal, LC90 = 880 ppm for mortality of Aedes aegypti larvae, LC90 = 408 ppm for mortality of Culex quinquefasciatus larvae, the non-polar extract is more toxic against Culex quinquefasciatus than Aedes aegypti larvae. The non-polar extract from pomelo (Citrus maxima) leaf has the potential of being developed aslarvicides for mosquito control. Abstrak Penggunaan insektisida kimia untuk mengontrol nyamuk dapat menyebabkanresistensi pada populasi nyamuk. Tujuan dari penelitian ini adalah untuk menemukannilai Konsentrasi Letal (LC90 ) ekstrak non polar daun jeruk bali (Citrus maxima) terhadap nyamuk setelah 24 jam. Larva yang digunakan dalam penelitian ini adalahlarva Aedes aegypti dan Culex quinquefasciatus. Kematian larva dihitung setelah 24 dan 48 jam.Uji larvasida menggunakan 20 ekor larva untuk setiap konsentrasi di dalam 100ml larutan ekstrak dengan lima replikasi. Ekstrak non polar diuji dengan konsentrasi 0ppm, 500 ppm, 1.375 ppm, 2.250 ppm, 3.125 ppm, dan 4.000 ppm. Angka kematianlarva dihitung setelah 24 jam paparan. Data dihitung dan dianalisa dengan analisisprobit. Hasil penelitian menunjukkan bahwa ekstrak non polar daun Citrus maximaberpotensi sebagai larvasida, Nilai LC90 = 880 ppm untuk kematian larva nyamuk Aedesaegypti, Nilai LC90 = 408 ppm untuk kematian larva nyamuk Culex quinquefasciatus, Ekstrak non polar lebih toksik terhadap larva Culex quinquefasciatus daripada larva Aedes aegypti. Ekstrak non polar dari daun Citrus maxima memiliki potensi untukdikembangkan sebagai larvasida untuk pengendalian nyamuk.

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“…15 Tanin membentuk kompleks dengan protein yang kaya prolin yang menyebabkan inhibisi sintesis protein sel. 16 Flavonoid masuk ke dalam tubuh serangga melalui sistem pernapasannya lalu menimbulkan kerusakan pada sistem pernapasan itu. Alkaloid dapat mendegradasi dinding sel dan merusak sel, serta juga memengaruhi sistem saraf dengan menghambat kerja enzim asetilkolin esterase.…”

Section: Pembahasanunclassified

Efek Larvasida Ekstrak Etanol Daun Pandan Wangi (<i>Pandanus amaryllifolius</i> Roxb.) terhadap Larva Nyamuk <i>Culex</i> sp

Putri

Wargasetia

Tjahjani

2017

GMHC

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AbstrakSalah satu cara pemberantasan nyamuk Culex yang merupakan vektor beberapa penyakit antara lain filariasis, Japanese encephalitis, St. Louis encephalitis, dan West Nile virus ialah dengan larvasida. Larvasida berbahan kimia (temephos) memiliki efek samping berbahaya bagi kesehatan dan lingkungan. Oleh sebab itu, dilakukan penelitian penggunaan daun pandan wangi (Pandanus amaryllifolius Roxb.) sebagai larvasida alami. Tujuan penelitian mengetahui apakah ekstrak etanol daun pandan wangi memiliki efek larvasida alami terhadap larva Culex sp. Penelitian dilakukan di Fakultas Kedokteran, Universitas Kristen Maranatha pada Februari-Juli 2016. Desain penelitian bersifat eksperimental laboratorik dengan metode rancangan acak lengkap. Efek larvasida ekstrak daun pandan wangi (EDPW) diuji terhadap 6 kelompok perlakuan (n=30, r=4) larva Culex sp. Kelompok I (EDPW 4%), II (EDPW 2%), III (EDPW 1%), IV (EDPW 0,5%), V (temephos sebagai kontrol positif), dan VI (akuades sebagai kontrol negatif). Data yang diambil ialah jumlah larva mati setelah pemberian bahan uji selama 24 jam. Analisis data dengan ANAVA dan uji Tukey HSD dengan nilai α=0,01. Hasil penelitian berupa persentase larva mati pada kelompok I (96,67%), II (79,17%), III (50%), dan IV (17,5%) menunjukkan perbedaan yang signifikan (p≤0,01) terhadap kelompok VI (1,67%). Tidak terdapat perbedaan signifikan (p>0,01) antara kelompok I dan V (100%). Simpulan, EDPW berefek sebagai larvasida terhadap larva nyamuk Culex sp dan EDPW 4% memiliki potensi setara dengan temephos. Kata kunci: Culex, daun pandan wangi, larvasida Larvicide Effect of Fragnant Pandan Leaves Ethanol Extract (Pandanus amaryllifolius Roxb.) Against Culex sp Mosquito Larvae AbstractOne way to eradicate Culex mosquitoes that are vector for several diseases such as filariasis, Japanese encephalitis, St. Louis encephalitis, and West Nile virus is with larvicide. Larvicide made from chemical (temephos) have harmful side effects to health and environment. Therefore research of fragnant pandan leaves (Pandanus amaryllifolius Roxb.) as natural larvicide was conducted. This study aims to find out whether fragnant pandan leaves ethanol extract has natural larvicide effect against Culex sp larvae. The study was conducted at Faculty of Medicine, Maranatha Christian University in February to July 2016. This study design was laboratoric experimental with complete randomized design. Larvicidal effect of fragnant pandan leaves extract (FPLE) was tested against 6 groups (n=30, r=4) Culex larvae. Group I (FPLE 4%), II (FPLE 2%), III (FPLE 1%), IV (0.5%), V (temephos as a positive control), and VI (aquadest as a negative control). The taken data was the number of larvae that died after administration of the substance for 24 hours. Data was analyzed by ANOVA and Tukey HSD test using α=0.01. The results of the study were the percentage of dead larvae in group I (96.67%), II (79.17%), III (50%), and IV (17.5%) showed a significant difference (p≤0.01) to group VI (1.67%). There were no significant difference (p>0.01) betwe...

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Aqueous Extracts of Seed and Peel of Carica Papaya Against Aedes Aegypti

Cited by 18 publications

References 10 publications

Medicinal Uses of Carica Papaya

Medicinal Uses of Carica Papaya

Potensi Larvasida dari Ekstrak Daun Jeruk Bali Citrus maxima terhadap dan Aedes aegypti dan Culex quinquefasciatus

Efek Larvasida Ekstrak Etanol Daun Pandan Wangi (<i>Pandanus amaryllifolius</i> Roxb.) terhadap Larva Nyamuk <i>Culex</i> sp

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