Apricot and pumpkin oils reduce plasma cholesterol and triacylglycerol concentrations in rats fed a high-fat diet

Ramadan, Mohamed Fawzy; Zayed, Rawia; Abozid, M. M.; Asker, Mohsen S.

doi:10.3989/gya.032911

Cited by 14 publications

(8 citation statements)

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“…These results are consistent with many previous studies [7,10] that have indicated the vital role played by diets containing unsaturated fatty acids in improving the levels of liver enzymes. Common carp and African catfish oils have high contents of unsaturated fatty acids (oleic and linoleic acids), in addition to their good amounts of omega 3 fatty acids.…”

Section: Impact Of Common Carp and African Catfish Oils Supplementatisupporting

confidence: 83%

“…Such findings coincide with that obtained by [6,7,61,62], who found that when experimental animals feed on high-fat diets, this leads to a significant increase in both AST and ALT activities compared with animals feed on normal diets. While those results don't agree with [22]; which may be explained by different feeding period on high-fat meals, where in the current study six weeks, while in the study referred to one month only.…”

Section: Impact Of Common Carp and African Catfish Oils Supplementatisupporting

confidence: 80%

“…In current study (table 4), it can be noticed that the PC group showed significantly higher levels of blood lipids compared with the NC group. On the other hand, CCO and ACO groups indicated bring down levels of lipid profile parameters which are in harmony with many researchers have addressed the relationship between the use of diets rich in oleic and linoleic acids and reduce the levels of lipid profile parameters [7,[51][52][53]; common carp oil and African catfish oil are characterized by high content of oleic (33.56 and 19.87%, respectively) and linoleic (18.65 and 14.66%, respectively). Values represent means±SD obtained from 8 rats, Means in the same row followed by the same letters do not differ significantly, and when the means followed by different letters differ significantly at (p ≥ 0.01) Also, the reduced effect of plasma lipid profile levels can be correlated with common carp and African catfish oils with a significant content of fatty acids EPA, DHA (omega-3 family), it is possible to confirm the previous recommendations of [54][55][56] who emphasized that omega-3 fatty acids play an important role in reducing the risk of atherosclerosis caused by elevated blood lipids.…”

Section: Impact Of Common Carp and African Catfish Oils Supplementatimentioning

confidence: 74%

“…The hypolipidemic effect may be attributed to the presence of high amounts of α-tocopherol (table 3) in both fish oils, as noted by a number of researchers in previous studies [7,57].…”

Section: Impact Of Common Carp and African Catfish Oils Supplementatimentioning

confidence: 78%

“…Many previous studies have confirmed that dieting play an important role in lowering blood lipids and reducing the harmful effects of saturated fat and cholesterol [7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

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Effect of Common Carp and African Catfish Oils on Rats Fed on High-Fat Diet

Abozid

Zein

El-halem³

2018

Int J Pharm Pharm Sci

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Objective: The present study was designed to study the effect of common carp and African catfish oils on the lipid profiles and liver functions in rats fed on high-fat diets, also fatty acids were assessed in both oils by gas-liquid chromatography (GLC). Methods:A biological experiment on rats was designed to raise fat in the diet and to study the effect of treatment with common carp and African catfish oils for 6 w (by the stomach tube) and then evaluate their impact on blood lipid profile and liver functions (Alanine transaminase [ALT], aspartate transaminase [AST] total protein and albumin).Results: GLC analysis of fatty acids (FAs) revealed the presence of oleic, palmitic, palmitolic, and linoleic acids more than 70% from total fatty acids in two oils. High-fat diet resulted in a significant increase in plasma lipid profile as well as liver functions. The treatment of rats fed high fat diets with common carp and African catfish oils resulted in a significant decrease in levels of triglycerides (TGs), total cholesterol (TC), low-denisty lipioprotein cholesterol (LDL-c), total cholesterol (TC)/high-denisty lipoprotein cholesterol (HDL-c) and TGs/HDL-c ratios compared with positive control group, while the same treatment with these oils resulted in a significant increase in HDL-c levels compared with positive control group. The intake of common carp and African catfish oils also significantly reduced ALT and AST activities compared with positive control group. Common carp and African catfish oils showed an anti-hyperlipidemic effect in rats feeding on hypercholesterolemic diets. Conclusion:It could be concluded that these fish oils have a promising role in reducing the harmful effects of high-fat diets.

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Section: Impact Of Common Carp and African Catfish Oils Supplementatisupporting

confidence: 83%

Section: Impact Of Common Carp and African Catfish Oils Supplementatisupporting

confidence: 80%

Section: Impact Of Common Carp and African Catfish Oils Supplementatimentioning

confidence: 74%

“…The hypolipidemic effect may be attributed to the presence of high amounts of α-tocopherol (table 3) in both fish oils, as noted by a number of researchers in previous studies [7,57].…”

Section: Impact Of Common Carp and African Catfish Oils Supplementatimentioning

confidence: 78%

“…Many previous studies have confirmed that dieting play an important role in lowering blood lipids and reducing the harmful effects of saturated fat and cholesterol [7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations