Appraisal of the burden of genital warts from a healthcare and individual patient perspective

Lefèbvre, Caroline; Kriekinge, Georges Van; Goncalves, Miguel; Sanjosé, Sílvia de

doi:10.1016/j.puhe.2011.01.016

Cited by 30 publications

(28 citation statements)

References 83 publications

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“…5 High incidence of AGW has been reported, ranging from 58 to 319 cases per 100 000 persons/year; with most cases occurring among young women (below 25 years). [6][7][8] These rates may be underestimated because many patients do not seek medical care and go undiagnosed. Recurrent respiratory papillomatosis is less frequent, with an incidence of 0.35-0.38 per 100 000 persons/years.…”

Section: Hpv Vaccine Efficacy In Anogenital Wartsmentioning

confidence: 99%

Human papillomavirus vaccine efficacy in the prevention of anogenital warts: systematic review and meta-analysis

Tejada¹,

Vargas²,

Benítes-Zapata³

et al. 2017

Salud Publica Mex

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http: //dx.doi.org/10.21149/7824 Resumen Objetivo. Revisar la evidencia sobre la eficacia de las vacunas contra el virus del papiloma humano en la prevención de lesiones no oncológicas (verrugas anogenitales [VAG], papilomatosis recurrente respiratoria y papilomatosis oral). Material y métodos. Realizamos una revisión sistemá-tica de ensayos clínicos aleatorizados. Empleamos modelos de efectos aleatorios, calculando riesgos relativos (RR) y sus intervalos de confianza al 95% (IC95%), utilizando el análisis por intención a tratar (ITT) y por protocolo (PP). Resultados. Seleccionamos seis estudios (n=27 078). Un estudio tuvo alto riesgo de sesgo y otro no fue incluido en el metanálisis. La vacuna cuadrivalente reduce el riesgo de VAG en 62% (RR: 0,38; IC95%:0,32-0,45; I2:0%) en el análisis ITT y en 95% (RR: 0,05; IC95%:0,01-0,25; I2:66%) en el análisis PP. Los análisis de subgrupos (mujeres y estudios con bajo riesgo de sesgo) proporcionaron resultados similares. Conclusión. La vacuna cuadrivalente es eficaz en la prevención de VAG en hombres y mujeres.

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Section: Hpv Vaccine Efficacy In Anogenital Wartsmentioning

confidence: 99%

Human papillomavirus vaccine efficacy in the prevention of anogenital warts: systematic review and meta-analysis

Tejada¹,

Vargas²,

Benítes-Zapata³

et al. 2017

Salud Publica Mex

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“…Patients who have visible genital warts can be infected simultaneously with multiple HPV types [5,58].…”

Section: Genital Benign Lesions Hpv-relatedmentioning

confidence: 99%

Oral HPV Infection: Current Strategies for Prevention and Therapy

Syrjänen

Termine

Capra³

et al. 2012

CPD

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Infection with High Risk (HR) Human Papillomaviruses (HPVs) is the main aetiological agent of Cervical Squamous Cell Carcinoma (CSCC) and also associated in a subgroup of other neoplasms, including Oropharyngeal Squamous cell Carcinoma (OPSCC). HPV infection, in genital as in oral mucosa, can also be subclinical or associated with benign proliferative lesions (common warts, condylomas, papillomas) caused mostly by infection with Low Risk (LR)-HPVs. In the last decades, extensive research has resulted in growing knowledge on HPV biology and specifically viral life cycle, biochemical properties of viral proteins and their interaction with the host proteins leading to potential new targets of prophylactic or therapeutic vaccines and therapies for HPV infection. In addition, notable progresses have been made in the field of diagnostics to detect HPV DNA or RNA. The recent epidemiological data suggest the significant changes in HPV endemic, due to the changes in sexual habits especially among young generations (i.e. early sexual debuts, multiple sexual partners, oral and anal sex); this scenario has urged on the need of adequate campaigns of primary (sexual education, vaccination programs) and secondary prevention (diagnostics of HPV-related diseases). Due to the growing interest on HPV infection and HPV related cancers, the authors made a narrative review of the literature on oral HPV infection and oral-genital transmission. After this, in view of the controversies about the strategies of therapy and prevention of HPV infection, the present review focuses on the current state of art about the available tools for the therapeutic and, if any, preventive management of oral HPV infection.

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“…[186] The genital warts are mostly common in younger people with the age of less than 25 years old and the transmission is more than 60% with an incubation time between 2 to 8 months. [192] Various clinical presentations are observed when keratinocytes respond to the HPV infection depending on the HPV type and the anatomical site. Genital warts are mainly associated with HPV6 and HPV11.…”

Section: Role Of Hpv In Non-cancerous Diseasesmentioning

confidence: 99%

“…[198] If these warts remain untreated, they can either regresses spontaneously or they can grow larger and become more numerous resulting in complicated cases. [192] Therefore, prevention HPV infection and therefore formation of these warts will be the optimum goal.…”

Section: Role Of Hpv In Non-cancerous Diseasesmentioning

confidence: 99%

The role of human papillomaviruses in cancer progression

Tulay¹,

Serakıncı²

2016

JCMT

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The importance of human papillomavirus (HPV) infection and its role in the progress of cancer have been widely evaluated. The understanding of HPV association with certain cancers, such as cervical cancer, is very well established. A big step forward in the prevention of HPV associated cancers with the use of early detection by screening strategies has also been taken. In the last decade, development of HPV vaccination has reduced the number of cases in HPV infections and infection induced cancers. In this report, we review the HPV pathogenesis and highlight the mechanism of HPV involvement in cancer development.

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Appraisal of the burden of genital warts from a healthcare and individual patient perspective

Cited by 30 publications

References 83 publications

Human papillomavirus vaccine efficacy in the prevention of anogenital warts: systematic review and meta-analysis

Human papillomavirus vaccine efficacy in the prevention of anogenital warts: systematic review and meta-analysis

Oral HPV Infection: Current Strategies for Prevention and Therapy

The role of human papillomaviruses in cancer progression

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