“…Recently, mitral annular velocity measured by tissue Doppler echocardiography, which measures velocities of regional cardiac wall, has been widely used for assessment of LV diastolic function (Ommen et al 2000;Nikitin and Witte 2004;Masugata et al 2008), because parameters from tissue Doppler echocardiography are less influenced by LV preload than are the parameters of conventional Doppler echocardiography. Thus, the parameters from tissue Doppler echocardiography do not show pseudonormaliza-tion even in cases with severe LV diastolic dysfunction (Sohn et al 1997), and can discriminate severe from mild LV diastolic dysfunction.…”