Application of the holographic interference microscope for investigation of ozone therapy influence on blood erythrocytes of patients in vivo

Tishko, T. V.; Titar, V. P.; Barchotkina, T.M.; Tishko, D. N.

doi:10.1109/caol.2003.1251242

Cited by 4 publications

(3 citation statements)

References 2 publications

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“…Similar results were obtained under investigation of blood specimens of patient with different diseases. Here we present the results of testing of 60 patients (men and women) with neurosensor hardness of hearing of different genesis 11,12 . The age of patients was from 18 to 67.…”

Section: Erythrocyte 3-d Morphology Investigation and Discussionmentioning

confidence: 99%

“…In blood of patients with different hematological diseases a lot of degenerative transformed erythrocytes are presented 18 . But now one can say, that erythrocytes change their morphology not only in hematological diseases 8,9 , but undergo morphological changes in diseases of different geneses [11][12][13][14]18 . In pathology different transformed shapes of erythrocytes are detected in blood.…”

Section: Erythrocyte 3-d Morphology Investigation and Discussionmentioning

confidence: 99%

“…3-D images of phase MOs were obtained for the first time when investigating the erythrocytes of patients suffering from hemolytic anemia 8 . The DHIM was used for different erythrocytes morphology investigations [9][10][11][12][13][14] . The problem occurred to be so actual, that lately a number of digital holographic microscopic techniques for noninvasive phase MOs investigations were proposed 15,16 .…”

Section: Introductionmentioning

confidence: 99%

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<title>Erythrocytes three-dimensional morphology by digital holographic interference microscopy</title>

2008

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We have developed the digital holographic interference microscope (DHIM) for real time three -dimensional (3-D) imaging and quantitative study of phase microscopic objects (MOs). The instrument integrates holographic interference microscope with digital processing of interferograms. The experimental procedure, allowing calculating microscopic objects thickness and 3-D imaging from the measured phase shift, is presented. The method has been applied to study 3-D morphology of red blood cells in norm, in pathology and under influence of physical and chemical factors in vivo. It has been found that morphologic changes of erythrocyte population had nonspecific character. Our investigations have proved that erythrocytes 3-D morphology reflects the state of a living organism and the level of its biological response on different external factors influence.

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Section: Erythrocyte 3-d Morphology Investigation and Discussionmentioning

confidence: 99%

Section: Erythrocyte 3-d Morphology Investigation and Discussionmentioning

confidence: 99%