Application of magnetic nanomaterials in bioanalysis

Yılmaz, Erkan; Sarp, Gökhan; Uzcan, Furkan; Özalp, Özgür; Soylak, Mustafa

doi:10.1016/j.talanta.2021.122285

Cited by 33 publications

(8 citation statements)

References 185 publications

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“…ZnO nanomaterials are a new multifunctional inorganic material. In recent years, it has been found that they show many special functions in catalysis, optics, magnetism, mechanics, and so on, which makes them have important application value in many fields such as ceramics, chemical industry, electronics, and optics ( Hu et al, 2021 ; Yilmaz et al, 2021 ; Singh, 2019 ; Singh, 2018 ). In addition, the biological functions of ZnO nanomaterials have attracted the attention of biomaterial scientists and surgeons.…”

Section: Introductionmentioning

confidence: 99%

Study on the biological effects of ZnO nanosheets on EBL cells

Lian

et al. 2022

Front. Bioeng. Biotechnol.

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In this study, the biological effects of ZnO nanosheets were initially investigated using embryonic bovine lung (EBL) cells cultured in vitro as a model. ZnO nanosheets were prepared by a hydrothermal method, and their structure and morphology were characterized, and their effects on EBL cell viability, oxidative stress, cell proliferation, and apoptosis were investigated. The results showed that 12.5 μg ml−1 ZnO nanosheets can cause morphological changes in EBL cells. The toxic effects of ZnO nanosheets on EBL cells were time-dependent. Caspase-3 activity in EBL cells changed under certain conditions with the introduction of 25 μg ml−1 ZnO nanomaterials, and EBL cell apoptosis was promoted. Under different concentration and time effects, ZnO nanosheets induced an increase in ROS levels in EBL cells, indicating that they have an oxidative damage effect on cells. The toxic effects of ZnO nanosheets on EBL cells were discussed, including concentration effect, time effect, and cytotoxic effect, which eventually led to cell oxidative damage.

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Section: Introductionmentioning

confidence: 99%

Study on the biological effects of ZnO nanosheets on EBL cells

Lian

et al. 2022

Front. Bioeng. Biotechnol.

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“…Nanoparticles, belonging to the nanomaterials group, are defined as unbound or aggregated objects with three external nanoscale dimensions in the range of 1-100 nm. Thus far, different nanoparticle types have been described, including metal nanoparticles, 30,31 magnetic nanomaterials, 32 silica, 33 hydrogels, 34 and carbon. 35,36 Among them, AuNPs have sparked a growing interest in the field of biology.…”

Section: Au Nanomaterialsmentioning

confidence: 99%

Framework nucleic acids directed assembly of Au nanostructures for biomedical applications

Liu

Chao

2023

Interdisciplinary Medicine

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Au nanostructures have elicited considerable interest because of their unique optical and physicochemical properties. These characteristics are mostly depended on the size, shape, chemical composition and dielectric environment of Au nanoparticles (AuNPs). Because of the easy chemical modification and programmable design of DNA molecules, they can not only combine to the surface of AuNP for improved stability, but also form the framework nucleic acids (FNAs) for direct assembly of different Au nanostructures with precise configuration and multiple dimensions. This paper starts with the synthesis and properties of Au nanomaterials. Followed by a brief introduction to the development of FNA nanotechnology, the FNA-directed assembly of Au nanostructures is discussed. Then, we focus on the biomedical applications of these Au nanostructures, including biosensing and therapeutics. In the end, we envision an insight into the remaining challenges and future perspectives toward FNA-based metal functional materials.

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“…The SPNE technique has been used to determine polychlorinated biphenyls, carbaryl, and mercury ions in environmental water and polycyclic aromatic hydrocarbons in drinking water [ 94 , 95 ]. In addition, magnetic NPs have been recommended primarily for blood, serum, plasma, milk, tissue extracts, and urine sample preparations [ 96 , 97 ].…”

Section: Sample Preparation Techniques In Bioanalyticsmentioning

confidence: 99%