Application of 670 nm InGaP laser and microcurrent favors the healing of second-degree burns in Wistar rats

Belli, M; Fernandes, Cleverson Rodrigues; Neves, Lia Mara Grosso; Mourão, V; Barbieri, R.; Esquisatto, Marcelo Augusto Marretto; Amaral, Maria Esméria Corezola do; Santos, Gláucia Maria Tech dos; Mendonça, Fernanda Aparecida Sampaio

doi:10.1088/1054-660x/25/2/025602

Cited by 12 publications

(12 citation statements)

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“…Tissue repair is a process characterized by interrelated events, into sequential phases: inflammatory, proliferative and remodeling under the action of specific cells, cytokines and various growth factors [6]. The TGF-b1 (Transforming Growth Factor), especially released in the early stages of this process, is secreted by keratinocytes, fibroblasts and platelets, acting as chemotactic for neutrophils and monocytes at the wound site [7,8].…”

Section: Introductionmentioning

confidence: 99%

“…Chromophore located in the mitochondria seem to absorb the laser's red and infrared light triggering increased protein synthesis, ATP production, cell proliferation, and reorganization of collagen [12]. The LLLT has stood out among the many therapeutic methods [6,[13][14][15] and has demonstrated in various studies that improves tissue repair as it promotes collagen synthesis and deposition, increased vascularity, inflammation reduction, accelerating the wound remodeling. In this way, it is a promising work tool in the burn wounds therapy [1,8,[15][16][17][18][19][20].…”

Section: Introductionmentioning

confidence: 99%

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Differing energy densities with laser 670 nm InGaP controls inflammation and collagen reorganization in burns

Maligieri

Neves

Morais

et al. 2017

Burns

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Differing energy densities with laser 670 nm InGaP controls inflammation and collagen reorganization in burns

Maligieri

Neves

Morais

et al. 2017

Burns

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“…burns in Wistar rats-the treatment of burn wounds is investigated as it has been a challenge due to their severity and associated multiple complications, and represents a major public health problem [40].…”

Section: • Application Of 670 Nm Ingap Laser and Microcurrent Favors mentioning

confidence: 99%

Introducing theLaser PhysicsandLaser Physics Lettershighlights of 2015

McKenna¹

2016

Laser Phys. Lett.

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The International Year of Light 2015 was a landmark for the laser and optics community pointing the way to a bright future for humanity and the environment. It is with great satisfaction that Laser Physics and Laser Physics Letters have published many notable articles that have contributed to the development of light-based technologies and breakthroughs in photonics. In recognition of their high quality, we present a selection of some of the most popular articles published by Laser Physics and Laser Physics Letters throughout 2015, all of which are believed to have the potential to make a high impact on future research directions. Those chosen are recognised for their high-interest with readers and importance in the field, providing a snapshot of the broad subject coverage and international make-up of both journals.Starting this year, we will be recognising and announcing annual highlights of a previous year for both journals. We hope that you find these highlights useful and look forward to publishing more cutting-edge work in the year ahead.Summary of the highlights articles: Physics of lasers• • Experimental investigation of the light shift effect in an optical-magnetic double resonance system-an experimental scheme for studying the light shift effect in an optical magnetic double resonance system by using 4 He atoms is demonstrated [3]. • Enhanced random lasing from a colloidal CdSe quantum dot-Rh6G system-randomlaser action in a system where optical amplification is provided by colloidal CdSe quantum dots triggered by the emission from Rhodamine 6 G is reported [4].• Ultra-short pulse generation in the hybridly mode-locked erbium-doped all-fiber ring laser with a distributed polarizer-ultra-short pulse generation in a dispersion-managed erbium-doped all-fiber ring laser hybridly mode-locked with boron nitride-doped singlewalled carbon nanotubes, in co-action with a nonlinear polarization evolution in the ring cavity with a distributed polarizer, is reported for the first time [5].• Analysis of pump excited state absorption and its impact on laser efficiency-a model to quantify the effect of excited state absorption at the pump wavelength on laser efficiency, threshold and heating is developed [6]. Fibre optics and fibre lasers• 80 fs passively mode-locked Er-doped fiber laser-an Er-doped laser that has an all-fiber design, including the dispersion compensation and external compression stages, forming a robust and compact device, is reported [7].• Bound-state fiber laser mode-locked by a graphene-nanotube saturable absorbermultiple bound states in a linear-cavity fiber laser mode-locked by a mixture of graphene and single-walled carbon nanotubes is experimentally observed [8]. Jarlath McKenna Publisher, Laser Physics and Laser Physics Letters Introducing the Laser Physics and Laser Physics Letters highlights of 2015Laser Physics Letters

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“…The development of new therapies that favor the repair of burn is important for better results regarding speed and quality of healing [8,9]. The use of medicinal plants as a treatment for wound healing has long been used [10,11].…”

mentioning

confidence: 99%

Casearia sylvestris Improved Cutaneous Burn Repair in Diabetic Rats

Martelli¹,

Theodoro²,

Gaspi³

et al. 2018

JPP

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Objectives: The burn repair associated with diabetes complications showed considerable changes in the healing process and the development of alternative therapies to favor the repair is important. This study investigated the efficacy of the Casearia sylvestris in the burn repair in diabetic and non-diabetic rats. Methods: The animals were divided into four groups (n = 20): (C) non-diabetics treated with carbopol gel; (G) non-diabetic treated with C. sylvestris extract in carbopol gel; (DM-C) diabetics treated with carbopol gel; (DM-G) diabetics treated with C. sylvestris extract in carbopol gel. Burn was induced using a metal plate (2 cm diameter/120 °C/20 sec). Samples were collected on the 3rd, 7th, 14th and 21st days after the injury for histomorphometric analysis (inflammatory infiltrate, fibroblasts, blood vessels and collagen), MPO (Myeloperoxidase) and NAG (N-Acetilglicosaminidase) dosage, hydroxyproline, glycosaminoglycans, TGF-β1, VEGF, collagen I and III. Key findings: C. sylvestris decreased the inflammatory process during the experimental period in diabetic and non-diabetic animals which has been demonstrated by MPO, NAG quantification, and TGF-β1 expression. C. sylvestris also increased blood vessels and decreased VEGF expression during the studied period in non-diabetic animals. Fibroplasia and collagenase were increased in all experimental periods in the DM-G group by means of de hydroxyproline quantification, collagen I, collagen III and glycosaminoglycans. Conclusions: C. sylvestris application can modulate favorably the time of inflammation and collagenous process in the repair of burn injuries in diabetic rats.

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Application of 670 nm InGaP laser and microcurrent favors the healing of second-degree burns in Wistar rats

Cited by 12 publications

References 68 publications

Differing energy densities with laser 670 nm InGaP controls inflammation and collagen reorganization in burns

Differing energy densities with laser 670 nm InGaP controls inflammation and collagen reorganization in burns

Introducing theLaser PhysicsandLaser Physics Lettershighlights of 2015

Casearia sylvestris Improved Cutaneous Burn Repair in Diabetic Rats

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