Antitumor activities of extracts from selected desert plants against HepG2 human hepatocellular carcinoma cells

Abstract

Context: Phytochemicals are produced by desert plants to protect themselves against stressful environments. They have been shown to be useful in preventing and fighting adverse pathophysiological conditions and complex diseases, including cancer. Although many desert plants have been investigated for their antitumor properties, a large number of them still remain to be explored for possible therapeutic applications in oncologic diseases.

Biological activities of the hydro-alcoholic and aqueous extracts of <i>Achillea fragrantissima</i> (Forssk.) grown in Jordan

“…A recent study reported cytotoxic effect of an aqueous extract of A. fragrantissima against HepG2 human hepatocellular carcinoma cells [33]. The MTT assay was used as a relative measure of cell viability to study the anti-proliferative activity of the aqueous and hydro-alcoholic A. fragrantissima extracts against the MCF-7 cells.…”

Study of antimicrobial effect of some plants of Lamiaceae family on Escherichia coli species isolated from children with urinary tract infection

“…Different species of Phlomis have been used in the treatment of diabetes, stomach ulcer, hemorrhoids and inflammations (26). In addition, the antibacterial, anticancer, and antioxidant activities have been reported for them (27,28). The main compounds of the essential oil of P. olivieri, obtained from its leaves, were Momtaz HE et al normal-octane (28.77%), camphor (13.32%), 1,8-cineol (12.24%), α-pinene (7.8%), and germacrene D (6.57%) (29).…”

Chemical composition and anticancer activity of Achillea fragrantissima (Forssk.) Sch. Bip. (Asteraceae) essential oil from Egypt

“…A recent study described cytotoxic effect of A. fragrantissima aqueous extract on HepG2 human hepatocellular carcinoma cells (Thoppil et al, 2013).…”