Antireflux surgery followed by bipolar electrocoagulation in the treatment of Barrett’s esophagus

KTP laser ablation of Barrett's esophagus after anti-reflux surgery results in long-term loss of intestinal metaplasia

“…A variety of endoscopic ablative therapies have been used (e.g., thermal laser, multipolar electrocautery, argon plasma coagulation, and photodynamic therapy) to eliminate Barrett's tissue [1,2,5,[17][18][19]23], but longterm follow-up evaluation of patients treated with these methods has not been reported. Previous studies have defined the success of ablation therapies on the basis of a decrease in the length of visible columnar-lined esophagus or evidence of partial squamous reepithelialization [1], but neither of these end points have been found to decrease the risk of progression to adenocarcinoma.…”

Impact of antireflux surgery on Barrett's esophagus

“…Salo et al reported complete regression in 11 patients (mean FU: 26 months) using laser coagulation in combination with laparoscopic Nissen fundoplication [47]. Montes could demonstrate complete regression of BE after a mean follow-up of 21.6 months in 14 patients treated with combined endoscopic electrocoagulation and laparoscopic fundoplication [48]. Another successful case using a similar technique was described by Montes et al [49].…”

Acid Suppression and Reepithelialization after Ablation of Barrett’s Esophagus

“…In the control group, which was followed for 21 months, the length of BE remained unchanged. Montes et al [42] reported on 14 postsurgical patients who were treated with bipolar thermal coagulation. All 14 had complete squamous reepithelialization, with no intestinal metaplasia found during a mean follow-up period of 21.6 months.…”