Antioxidative stress potential of Cinnamomum zeylanicum in humans: a comparative cross-sectional clinical study

Ranjbar, Akram; Ghasmeinezhad, Sara; Zamani, Hosnieh; Malekirad, Ali Akbar; Baiaty, Akram; Mohammadirad, Azadeh; Abdollahi, Mohammad

doi:10.1586/14750708.3.1.113

Cited by 29 publications

(33 citation statements)

References 15 publications

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“…Cinnamon constituents possess antioxidant action and may prove beneficial against free radical damage to cell membranes (Dragland et al 2003). Cinnamon has a marked antioxidant potential and may be beneficial in alleviating the complications of many illnesses related to oxidative stress in humans (Ranjbar et al 2006). Cinnamon extracts are used regularly as food antioxidants, also improving food palatability (Mancini-Filho et al 1998).…”

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confidence: 99%

Effect of Cinnamomum zeylanicum Essential Oil on Antioxidative Status in Broiler Chickens

et al. 2009

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The experiment was conducted to investigate the effects of Cinnamomum zeylanicum essential oil on antioxidant status of chickens. Thirty-two female Ross 308 hybrid broilers were fed one of four diets supplemented with 0%, 0.1%, 0.05% and 0.025% of essential oil for 38 days. Blood, liver, kidney and duodenal epithelium were collected for the subsequent evaluation of antioxidant status. Feeding of adiet supplemented with 0.1% of essential oil significantly decreased the concentration of malondialdehyde (MDA) in plasma and duodenal mucosa in comparison with the control group (0%). The activities of glutathione peroxidase (GPx) were significantly higher in blood of chicks fed the diet containing 0.1% of essential oil. Diets containing 0.05% and 0.025% of essential oil reduced alanine amino transferase (ALT) activity in plasma in comparison with the control group. Blood phagocytic activity significantly increased in chickens fed the diet supplemented with 0.1% and the index of phygocytic activity was affected by the diet containing 0.025% of essential oil in comparison with the control group. The present investigation shows that Cinnamomum zeylanicum essential oil exhibits a significant antioxidant activity in fattening chickens and can be used as a source of antioxidant in dietary supplement.

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confidence: 99%

Effect of Cinnamomum zeylanicum Essential Oil on Antioxidative Status in Broiler Chickens

et al. 2009

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“…Molecules of Poly-Phenol Polymeric are another derivations of Proanthocyanin which exist in the cinnamon extract (Vermerris & Nicholson, 2006). Relevant Poly-Phenols can present information from Amyloid, independent of oxidation conditions, thus they can prevent neurotoxicity induced by beta-amyloid and assist symptoms of Alzheimer (Ranjbar , 2006). The capability of purifying free radicals is one of the signif icant specif ications of anti-oxidation to minimize oxidation cells.…”

Section: Discussionmentioning

confidence: 99%

Intraperitoneal Injection of cinnamon extract (Cinnamomum zeylanicum) on Passive Avoidance Learning in Rats with Streptozotocin-induced Alzheimers Disease

Ahmadi¹,

Toloeghamary²,

Pishghadam³

2017

ambi

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“…This traditional plant is extensively used for the treatment of different kidney ailment and due to the sweet bark of plant, it is known as sweet wood (Willis, 1973). The plant may have protective role in alleviating the sign and symptoms of many diseases due to oxidative stress (Ranjbar et al, 2006). The extracts of Cinnamon regularly used as food antioxidants (Mancini-Filho et al, 1998).…”

Section: Introductionmentioning

confidence: 99%

“…On the basis of above discussed text; C. zeylanicum comprise a number of remedial properties, particularly determined as antioxidant and free radical scavenging properties may due to strong phenolic contents (Ranjbar et al, 2006;Mancini-Filho et al, 1998;Tomaino et al, 2005;Lee and Shibamoto, 2002;Hasani-Ranjbar et al, 2009;Dhuley, 1999), which has been reported to be responsible for the amelioration of gentamicin induced renal damage (Ali and Mousa, 2001). Most importantly, the powdered bark of C. zeylanicum is used traditionally for the treatment of various kidney problems like kidney stones, renal colic and believed to have a tonic effect on kidney.…”

Section: Introductionmentioning

confidence: 99%

Bioactive traditional plant <i>Cinnamomum zeylanicum</i> successfully combat against nephrotoxic effects of aminoglycosides

Ullah

Khan

et al. 2013

Bangladesh J Pharmacol

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Cinnamomum zeylanicum is traditionally used for the treatment of bladder and kidney problems; believed to have kidney tonic effects. The prime objective of the current study was to explore the nephroprotective effects of the plant due to its strong antioxidant properties, to provide experimental facts for their traditional use. Daily dose of 200 mg/kg of plant extract was employed alone and in combination with gentamicin for a period of twenty one days in rabbits. Biochemical kidney functioning parameters were assessed thrice throughout study period. Histopathological examination of the kidneys was performed on the last day of experimental period. Present study showed that C. zeylanicum significantly attenuated renal functional and histological changes associated with gentamicin as assessed by urea, creatinine, uric acid, electrolytes, urinary protein, and histopathological examination. The plant extract successfully proved to have strong nephroprotective properties, especially against aminoglycosides induced nephrotoxicities. Article Info

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Antioxidative stress potential of Cinnamomum zeylanicum in humans: a comparative cross-sectional clinical study

Cited by 29 publications

References 15 publications

Effect of Cinnamomum zeylanicum Essential Oil on Antioxidative Status in Broiler Chickens

Effect of Cinnamomum zeylanicum Essential Oil on Antioxidative Status in Broiler Chickens

Intraperitoneal Injection of cinnamon extract (Cinnamomum zeylanicum) on Passive Avoidance Learning in Rats with Streptozotocin-induced Alzheimers Disease

Bioactive traditional plant <i>Cinnamomum zeylanicum</i> successfully combat against nephrotoxic effects of aminoglycosides

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