Antioxidant properties of <i>Artemisia absinthium</i> accelerate healing of experimental Achilles tendon injury in rabbits

Hoseinian, Ali; Moslemi, Hamidreza; Sedaghat, Reza

doi:10.2478/hepo-2018-0003

Cited by 6 publications

(4 citation statements)

References 32 publications

(29 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It was shown that polysaccharides obtained from A. absinthium possess immunomodulatory effect through the Th1 response initiation and activation of NO synthesis [57]. Hoseinian et al [58] indicated the wound healing activity of A. absinthium by triggering the curative development of the wound of Achilles tendon in rabbit. This may be related to the free radical scavenging of β-thujone and β-pinene isolated from A. absinthium [12].…”

Section: Immuno-modulatory and Wound Healing Activitiesmentioning

confidence: 99%

Bioactive Compounds, Pharmacological Actions, and Pharmacokinetics of Wormwood (Artemisia absinthium)

et al. 2020

View full text Add to dashboard Cite

Plants have been used since ancient times to cure certain infectious diseases, and some of them are now standard treatments for several diseases. Due to the side effects and resistance of pathogenic microorganisms to antibiotics and most drugs on the market, a great deal of attention has been paid to extracts and biologically active compounds isolated from plant species used in herbal medicine. Artemisia absinthium is an important perennial shrubby plant that has been widely used for the treatment of several ailments. Traditionally, A. absinthium has always been of pharmaceutical and botanical importance and used to manage several disorders including hepatocyte enlargement, hepatitis, gastritis, jaundice, wound healing, splenomegaly, dyspepsia, indigestion, flatulence, gastric pain, anemia, and anorexia. It has also been documented to possess antioxidant, antifungal, antimicrobial, anthelmintic, anti-ulcer, anticarcinogenic, hepatoprotective, neuroprotective, antidepressant, analgesic, immunomodulatory, and cytotoxic activity. Long-term use of A. absinthium essential oil may cause toxic and mental disorders in humans with clinical manifestations including convulsions, sleeplessness, and hallucinations. Combination chemotherapies of artemisia extract or its isolated active constituents with the currently available antibabesial or anti-malarial drugs are now documented to relieve malaria and piroplasmosis infections. The current review examines the phytoconstituents, toxic and biological activities of A. absinthium.

show abstract

Section: Immuno-modulatory and Wound Healing Activitiesmentioning

confidence: 99%

Bioactive Compounds, Pharmacological Actions, and Pharmacokinetics of Wormwood (Artemisia absinthium)

et al. 2020

View full text Add to dashboard Cite

show abstract

“…et al 2019). The use of A. absinthium extract can improve the healing process (Hoseinian et al 2018).…”

Section: Asterаceae Familymentioning

confidence: 99%

Biodiversity of wild spice plants of the Central Kazakhstan region and their medicinal potential

et al. 2022

View full text Add to dashboard Cite

Abstract. Pozdnyakova Y, Omarova G, Murzatayeva A, Tankibaeva N. 2022. Biodiversity of wild spice plants of the Central Kazakhstan region and their medicinal potential. Biodiversitas 23: 4609-4625. The Central Asian region stretches from the Caspian Sea in the west to the border of western China in the east. Central Kazakhstan occupies the space of steppe and semi-desert zones within the Turgay Plateau in the west and the Kazakh Uplands in the center and in the east. Due to the remoteness of the steppes of Central Kazakhstan from the oceans, the climate in the region is extremely continental and arid. Due to this, the diversity of plant species is quite small. In this work, we have studied the biodiversity of wild herbs growing in the climatic conditions of Central Asia. We also assessed the prospects of the found plant species as medicines. This study took place as part of the traditional summer practice of biology students in the period July-August 2019. The main method used in the field research was route reconnaissance. As a result of field research, 40 wild spice plant species belonging to 17 families were found. Among them, the most numerous are the families Lamiaceae - 9 species, Brassicaceae - 6 species, Apiaceae - 5 species, Asteraceae - 4 species, the families Rosaceae and Fabaceae - 2 species of herbs. All of these species are mentioned in a number of old recipes and can be revived and re-recommended for widespread use. A critical assessment of the literature on the medicinal properties of the studied spices irrefutably shows that they have enormous health potential. Based on the data obtained, it can be concluded that wild spice plants growing in the territory of Central Kazakhstan have a wide range of taste diversity and prospects for successful commercial exploitation.

show abstract

“…The amount of phenolic and flavonoid compounds in wormwood is positively correlated with its antioxidant capacity [ 18 , 19 ]. The health benefits of Artemisia include its antioxidant [ 20 , 21 , 22 , 23 , 24 ], neuroprotective [ 25 ], hepatoprotective [ 26 ], anti-inflammatory [ 27 ], renoprotective [ 28 ], and gastroprotective effects, and its digestive [ 29 ] and antibacterial activities [ 30 , 31 , 32 ]. The antibacterial activity of plants is a topic of interest for researchers because of the increasing antibacterial resistance to medications designed to kill them.…”

Section: Introductionmentioning

confidence: 99%

Antibacterial and Phytochemical Screening of Artemisia Species

et al. 2023

View full text Add to dashboard Cite

Taking into account the increasing number of antibiotic-resistant bacteria, actual research focused on plant extracts is vital. The aim of our study was to investigate leaf and stem ethanolic extracts of Artemisia absinthium L. and Artemisia annua L. in order to explore their antioxidant and antibacterial activities. Total phenolic content (TPC) was evaluated spectrophotometrically. Antioxidant activity was evaluated by DPPH and ABTS. The antibacterial activity of wormwood extracts was assessed by minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) in Escherichia coli, Staphylococcus aureus, Listeria monocytogenes, and Salmonella enteritidis cultures, and by zone of inhibition in Klebsiella carbapenem-resistant enterobacteriaceae (CRE) and Escherichia coli extended-spectrum β-lactamases cultures (ESBL). The Artemisia annua L. leaf extract (AnL) exhibited the highest TPC (518.09 mg/mL) and the highest expression of sinapic acid (285.69 ± 0.002 µg/mL). Nevertheless, the highest antioxidant capacity (1360.51 ± 0.04 µM Trolox/g DW by ABTS and 735.77 ± 0.02 µM Trolox/g DW by DPPH) was found in Artemisia absinthium L. leaf from the second year of vegetation (AbL2). AnL extract exhibited the lowest MIC and MBC for all tested bacteria and the maximal zone of inhibition for Klebsiella CRE and Escherichia coli ESBL. Our study revealed that AbL2 exhibited the best antioxidant potential, while AnL extract had the strongest antibacterial effect.

show abstract

Antioxidant properties of Artemisia absinthium accelerate healing of experimental Achilles tendon injury in rabbits

Cited by 6 publications

References 32 publications

Bioactive Compounds, Pharmacological Actions, and Pharmacokinetics of Wormwood (Artemisia absinthium)

Bioactive Compounds, Pharmacological Actions, and Pharmacokinetics of Wormwood (Artemisia absinthium)

Biodiversity of wild spice plants of the Central Kazakhstan region and their medicinal potential

Antibacterial and Phytochemical Screening of Artemisia Species

Contact Info

Product

Resources

About