Antioxidant Effect of Roasted Barley (&amp;lt;i&amp;gt;Hordeum vulgare&amp;lt;/i&amp;gt; L.) Grain Extract towards Oxidative Stress &amp;lt;i&amp;gt;in Vitro&amp;lt;/i&amp;gt; and &amp;lt;i&amp;gt;in Vivo&amp;lt;/i&amp;gt;

Omwamba, Mary; Li, Feng; Sun, Guangxi; Hu, Qiuhui

doi:10.4236/fns.2013.48a017

Cited by 26 publications

(16 citation statements)

References 33 publications

(38 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Using in vitro methods, have previously shown, that purified DHB could scavenge DPPH radical, hydroxyl radical and intracellular ROS. DHB was also shown to chelate free Fe 2+ thereby preventing its reaction with H 2 O 2 and consequent generation of hydroxyl radical …”

Section: Discussionmentioning

confidence: 99%

3,4‐Dihydroxybenzaldehyde lowers ROS generation and protects human red blood cells from arsenic(III) induced oxidative damage

Maheshwari

Khan

Mahmood

2018

Environmental Toxicology

View full text Add to dashboard Cite

Arsenic (As) is a potent environmental toxicant and chronic exposure to it results in various malignancies in humans. Oxidative stress has been implicated in the etiopathogenesis of As-induced toxicity. This investigated the protective effect of plant antioxidant 3,4-dihydroxybenzaldehyde (DHB) on sodium meta-arsenite (SA), an As-(III) compound, induced oxidative damage in human red blood cells (RBC). The RBC were first incubated with different concentrations of DHB and then treated with SA at 37°C. Hemolysates were prepared and assayed for various biochemical parameters. Treatment of RBC with SA alone enhanced the generation of reactive oxygen species and increased lipid and protein oxidation. Reduced glutathione levels, total sulfhydryl content and cellular antioxidant power were significantly decreased in SA alone treated RBC, compared to the untreated control cells. This was accompanied by membrane damage, alterations in activities of antioxidant enzymes and deranged glucose metabolism. Incubation of RBC with DHB, prior to treatment with SA, significantly and dose-dependently attenuated the SA-induced changes in all these parameters. Scanning electron microscopy of RBC confirmed these biochemical results. Treatment of RBC with SA alone converted the biconcave discoids to echinocytes but the presence of DHB inhibited this conversion and the RBC retained their normal shape. These results show that DHB protects human RBC from SA-induced oxidative damage, most probably due to its antioxidant character.

show abstract

Section: Discussionmentioning

confidence: 99%

3,4‐Dihydroxybenzaldehyde lowers ROS generation and protects human red blood cells from arsenic(III) induced oxidative damage

Maheshwari

Khan

Mahmood

2018

Environmental Toxicology

View full text Add to dashboard Cite

show abstract

“…Kim, Bo, and Sang () showed that barley supplies important antioxidants that prevent oxidative stress when consumed in large amounts. Omwamba, Li, Sun, and Hu () showed that roasted barley prevents oxidative stress in mice. Lahouar et al () showed that whole grain barley has an anticarcinogenic effect on azoxymethane‐induced colon carcinogenesis in rats.…”

Section: Introductionmentioning

confidence: 99%

Characteristics of three typical Chinese highland barley varieties: Phenolic compounds and antioxidant activities

Shen

Zhang

et al. 2017

J Food Biochem

View full text Add to dashboard Cite

The objective of this study was to determine the phytochemical profiles and antioxidant activities of three highland barley varieties. The free, bound, and total phenolic content of highland barley, respectively ranged from 44.52 to 178.37 mg gallic acid equivalents (GAE)/100 g dry weight (D. W.), 121.69-302.55 mg GAE/100 g D. W., and 166.21-480.92 mg GAE/100 g D. W. Besides, the free, bound, and total flavonoid content, respectively, ranged from 15.71 to 35.18 mg rutin equivalents (RE)/100 g D. W., 39.37-86.93 mg RE/100 g D. W., and 59.13-102.64 mg RE/100 g D. W. The 2,2-diphenyl-1-picrylhydrazyl radical scavenging abilities, oxygen radical absorbance capacities, ferric reducing antioxidant power values, and cellular antioxidant activities of the bound extractions of highland barley were higher than those of the free extractions. However, the free polyphenol extracts had stronger inhibitory effects on HepG2 cell proliferation than the bound extracts. Practical applicationsHighland barley is a principal food crop that is widely cultivated in the west and southwest regions of China. Highland barley is usually rich in phenolic compounds, however, the phenolic compounds content and antioxidant activities of highland barley were underestimated because the bound phytochemical fraction was not included in the analysis. In this study, three highland barleys from different region of China were used to analysis the free and bound total phenolics and total flavonoids, as well as the antioxidant activities.

show abstract

“…Perendangan beras di Thailand dan Korea (Lee, et al 2003), perendangan serealia di India dan perendangan gandum di Arab Saudi (Sandhu et al, 2015), perendangan gandum di China (Hu et al, 2011) dan perendangan barley di China (Omwamba et al, 2013) dan India (Baba et al, 2011dan Mishra et al, 2014.…”

Section: Pendahuluanunclassified

Komposisi Gizi Dan Pati Tepung Beras Rendang Dari Beberapa Sentra Produksi Di Kota Payakumbuh Sumatera Barat

Refdi

Fajri

2017

j. teknol. pertan. n.a.

View full text Add to dashboard Cite

Penelitian ini bertujuan untuk mengetahui komposisi zat gizi dan pati Tepung Beras Rendang yang berasal dari beberapa sentra produksi di Kota Payakumbuh Sumatera Barat dan dibandingkan dengan Tepung Beras Ketan Putih (TBKP) sebagai bahan baku. Hal yang ingin diteliti adalah pengaruh perendangan tepung beras ketan terhadap komposisi gizi dan pati bahan. Komposisi gizi yang diamati adalah kadar air, kadar protein, kadar lemak, kadar abu, dan kadar karbohidrat, sedangkan komposisi pati yang diamati adalah kadar amilosa dan amilopektin bahan. Data yang diperoleh kemudian dianalisis secara statistik dengan Paired T-test (Uji T-berpasangan) menggunakan program SPSS 17. Berdasarkan hasil penelitian didapatkan bahwa proses perendangan TBKP memberikan pengaruh yang nyata (P<0,05) untuk menurunkan kadar air, kadar protein, kadar lemak dan secara nyata (P<0,05) meningkatkan kadar karbohidrat, kadar abu dan kadar amilosa

show abstract

Antioxidant Effect of Roasted Barley (<i>Hordeum vulgare</i> L.) Grain Extract towards Oxidative Stress <i>in Vitro</i> and <i>in Vivo</i>

Cited by 26 publications

References 33 publications

3,4‐Dihydroxybenzaldehyde lowers ROS generation and protects human red blood cells from arsenic(III) induced oxidative damage

3,4‐Dihydroxybenzaldehyde lowers ROS generation and protects human red blood cells from arsenic(III) induced oxidative damage

Characteristics of three typical Chinese highland barley varieties: Phenolic compounds and antioxidant activities

Komposisi Gizi Dan Pati Tepung Beras Rendang Dari Beberapa Sentra Produksi Di Kota Payakumbuh Sumatera Barat

Contact Info

Product

Resources

About