Antioxidant, Antimicrobial and Cytotoxicity Activities of Acacia farnesiana (L.) Willd. Leaves Ethanolic Extract

Abstract

Solvents and extraction procedures, [4] together with different methods available to evaluate antioxidant [5] and antibacterial activity [6] have been contributed to the variation of observed plant extract effects. In frequently reported studies, polyphenols have been suggested as responsible for the potent biological activities of extracts prepared using methanol and ethanol. [7] Acacia farnesiana is a plant from the subfamily Mimosoideae of Leguminosae (Fabacea). It is well known cultivated for its flower to be utilized in the production of cassie perfume. [8] The plant is also known for its ethnopharmacological properties and a number of scientific studies have been carried out previously. For instance, the bronchodilator and anti-inflammatory effect of glycosidal fraction of A. farnesiana was reported. [9] The root is reputed active against snake bite venom [10] and compounds of diterpenes and flavonoids were previously isolated from the root extract. [11] The methanolic extract of Acacia farnesiana bark exhibited antidiarrhoeal activity against castor oil and magnesium sulphate induced diarrhea along with antimicrobial activity against common pathogens responsible for diarrhoea in vitro. [12] Previously, the anti-inflammatory property of the

Insights for the Valorization of Biomass from Portuguese Invasive Acacia spp. in a Biorefinery Perspective

“…Extracts of A. dealbata showed antibacterial activity of the same magnitude as that observed with Eucalyptus nicholii [54] and Olea europaea [55]. Quercetin-galloylglucoside, rutin, quercetin-pentoside, diosmetin diglycoside and especially quercetin-deoxyhexoside, were found in the A. farnesiana extract and are suspected to be involved in the observed bioactivity [57]. Besides antimicrobial properties, the A. farnesiana extract was proved to have low toxicity and good antioxidant properties, accessed by the ability to chelate iron and reduce the power and scavenging capacity against nitric oxide and DPPH free radicals [57].…”

“…Quercetin-galloylglucoside, rutin, quercetin-pentoside, diosmetin diglycoside and especially quercetin-deoxyhexoside, were found in the A. farnesiana extract and are suspected to be involved in the observed bioactivity [57]. Besides antimicrobial properties, the A. farnesiana extract was proved to have low toxicity and good antioxidant properties, accessed by the ability to chelate iron and reduce the power and scavenging capacity against nitric oxide and DPPH free radicals [57]. In A. karroo, multiple classes of compounds were already identified in their leaves that may be involved in its antimicrobial activity, such as flavonoids, phenols, phytosterols, proanthocyanidin, tannins or terpenes [83].…”

Antioxidant activity and protection against oxidative-induced damage of Acacia shaffneri and Acacia farnesiana pods extracts: in vitro and in vivo assays

“…We reported [ 4 ] an important polyphenol content in A. farnesiana (AF) complete plant (38,170 mg gallic acid equivalents/kg dry matter). Many other compounds in AF have been reported such as flavonoids (12 mg rutin equivalents/100 g dry matter), carotenoids, coronaric, oleic, linoleic and linolenic acids, and some aldehydes (geraniol and geranyl acetate) [ 3 , 6 , 21 ].…”

Amazing Antimicrobial and Wound Healing Potential of Acacia Catechu Bark Extracts- A Review

“…In this section we have focused on antimicrobial and wound healing activities of Acacia catechu wild bark extracts. A. catechu Wild is one of the remarkable medicinal plants having immense medicinal potential in almost all parts of its body [15]. From long it has been widely using in Ayurveda and other medical systems for many diseases, both as an external and oral ingredient [16,17].…”