Amazing Antimicrobial and Wound Healing Potential of Acacia Catechu Bark Extracts- A Review

Abstract

Plants are not only the source of food, oxygen, and shelter, but the same are also a potential foundation of medicines. Many natural and plant-derived antimicrobial and wound healing compounds have been recognized. In the present review, we have studied the main bioactive components of Acacia catechu with their medicinal roles. Most of these bioactive components are secondary metabolites which are produced by plants as side products of certain physiological reactions and are of no use for the plant itself. These components have been reported for their medicinal properties. In this review, we have mentioned some antibacterial, antifungal, and wound healing properties of A. catechu with its known bioactive components. The aim of this review article is, to enlist the possible potent bioactive components of the plant, against pathogenic microbes that can replace the use of chemicals and synthetic antibiotics for the treatment of skin infections and other diseases.

Evaluation of Comparative in Vitro Free Radical Scavenging Potential of Bark Extracts of Acacia Catechu

“…And possibly the higher drug concentration may have less efficacy due to possible adverse effects, as have been reported earlier [3,23,[33][34][35][36][37]. Similar, concentrationdependent scavenging of DPPH radicles was also reported by earlier scientists [5,19,[32][33][34][35][36].…”

“…The lower activity of drugs at higher concentrations may indicate that some of their components act as pro-oxidants or might be taking part in some other metabolic activities that decrease the overall protective activity of drugs [5,32,36]. And possibly the higher drug concentration may have less efficacy due to possible adverse effects, as have been reported earlier [3,23,[33][34][35][36][37]. Similar, concentrationdependent scavenging of DPPH radicles was also reported by earlier scientists [5,19,[32][33][34][35][36].…”

“…The use of organic solvents, such as ethyl acetate, ethanol, methanol, hexane, and chloroform, for extraction purposes results in the production of compounds that possess unique chemical compositions. Consequently, these compounds exhibit various physiological and pharmacological effects [26,[32][33][34][35].…”

“…The DPPH scavenging test is considered a potential indication of antioxidants since it offers an easy, practical, quick, and replicable method for obtaining results [1,5,34,40]. The assessment of the overall antioxidant capacity of the plant extracts in this study is contingent upon the levels of DPPH free radicals, the concentrations of the extract, and the scavenging efficacy of the bioactive components present in the drug extract [33][34][35]41]. The use of these antioxidant assays is vital in the investigation of natural sources of antioxidants and their potential applications as functional foods, pharmaceuticals, and food additives [42,43].…”

“…The main aim of this study was to investigate the relative antioxidative potential of different extracts in a concentration-dependent manner on the studied parameter. Moreover, seasonal changes have also been documented to affect the phytochemistry of plants [33]; hence, samples collected in different seasons of 2 successive years were also studied using the same parameter. Since in vitro studies provide a simplified model for investigation, the outcomes may be indicative of effects in in vivo systems [1,6,7].…”