Antioxidant and antimicrobial activity of<i>alpinia officinarum</i>

Srividya, A. R.; Dhanabal, S. P.; Misra, VK; Suja, G

doi:10.4103/0250-474x.62233

Cited by 70 publications

(48 citation statements)

References 6 publications

(5 reference statements)

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“…Esses fatores podem interferir na composição química e proporção de metabólitos secundários dos extratos (Czelusniak et al, 2012). Extratos hidroalcoólicos das raízes de Alpinia officinarum determinaram ação sobre S. aureus, proporcionalmente superior àquela induzida pelo EE de A. zerumbet (Srividya et al, 2010). Extratos metanólicos e aquosos de Alpinia allughas e Alpinia calcarata induziram maiores inibições sobre S. aureus, quando preparados a partir das raízes em comparação com aqueles produzidos com folhas das mesmas espécies (Bhunia;Mondal, 2012).…”

Section: Resultsunclassified

Composição química e eficácia do óleo essencial e do extrato etanólico de Alpinia zerumbet sobre Staphylococcus aureus

Castro

Lima

Vasconcelos³

et al. 2016

Arq. Inst. Biol.

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ABSTRACT:The present work describes the antibacterial activity of the essential oil and the ethanol extract from leaves of Alpinia zerumbet (colônia) on Staphylococcus aureus strains isolated from cows with subclinical mastitis and standard strains ATCC 29213 and ATCC 25923, using the agar diffusion method. Ten treatments containing different concentrations of essential oil and ethanol extract (100.0; 50.0; 25.0; 12.5 and 6.3 mg.mL ) and the control group (50% ethyl alcohol and 1% Tween solutions) were used for antimicrobial testing. The major constituents of the essential oil were p-cimeno (32.72%), 1.8-cineol (24.05%) and 4-terpineol (20.23%), which were determined by gas chromatographymass spectrometry and gas chromatography -flame ionization detector (CG-MS/FID). Ellagic acid and three flavonoids (rutin, quercetin and campferol) were detected in the ethanol extract by means of high performance liquid chromatography-photodiode array detector (HPLC-PDA). All strains showed sensitivity to the treatments with essential oil and the ethanol extract. The best response was obtained with A. zerumbet essential oil at a 100 mg.mL ) e o grupo controle (álcool etílico a 50% e Tween a 1%). Os constituintes majoritários do óleo essencial foram p-cimeno (32,72%), 1,8-cineol (24,05%) e 4-terpineol (20,23%), sendo esses determinados por cromatografia a gás acoplada a espectrometria de massas e cromatografia a gás com detector de ionização de chama (CG-EM/DIC). No extrato etanólico foi detectado o ácido elágico e três flavonoides: rutina, quercetina e campferol, por meio de cromatografia a líquido de alta eficiência acoplada a detector de arranjo de diodo (CLAE-DAD). Todas as cepas apresentaram sensibilidade aos tratamentos com óleo essencial e extrato etanólico. A melhor resposta foi obtida com o óleo essencial de A. zerumbet que, na concentração de 100 mg.mL -1 proporcionou inibição total do crescimento bacteriano. Esses resultados sugerem o potencial antibacteriano do óleo essencial e do extrato etanólico de A. zerumbet no controle da mastite bovina. Composição química e eficácia do óleo essencial e do extrato etanólico de Alpinia zerumbet sobre Staphylococcus aureus PALAVRAS-CHAVE:

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Section: Resultsunclassified

Composição química e eficácia do óleo essencial e do extrato etanólico de Alpinia zerumbet sobre Staphylococcus aureus

Castro

Lima

Vasconcelos³

et al. 2016

Arq. Inst. Biol.

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“…This activity has been expressed as % inhibition DPPH radical scavenging. The test was carried out in triplicate and the results are averaged [6]. The percentage inhibitory activity of DPPH radical was calculated by using the following formula Where A0 is absorbance of control and A1…”

Section: Dpph Radical Scavenging Activitymentioning

confidence: 99%

Study of Antioxidant Activity of Formononetin by in Vitro Method

Vishnuvathan

Lakshmi

Srividya

2017

Int J Pharm Pharm Sci

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Objective: Now the important field of research in phytomedicine is to search a new plant source as well as new phytoconstituents that have fewer side effects and low cost with the free radical scavenging activity. Methods:Different in vitro models such as DPPH, hydroxyl radical, hydrogen peroxide radical, nitric oxide radical and superoxide radical scavenging activity were performed using different concentrations of formononetin ranging from 0.1-50 μg/ml.Results: Formononetin showed only 84.39% inhibitory activity against DPPH radical and it was found to be 16 % less than the butylated hydroxytoluene with the IC 50 value of 4.65 μg/ml concentration. In scavenging hydroxyl radicals, formononetin inhibited only 67.63% with the IC50 value of 9.48 μg/ml concentration and it showed 12 % lesser inhibitory activity than standard alpha-tocopherol. Formononetin could able to scavenge maximum 73.53% of hydrogen peroxide radicals with the IC50 value of 4.75 μg/ml and its activity of scavenging hydrogen peroxide were found to be 10 % less than the standard ascorbic acid. Formononetin showed 94.33 % nitric oxide radical inhibitory activity with the IC50 value of 5.0 μg/ml and it showed 6% lesser activity when compared to standard quercetin. Formononetin showed 94.79 % activity against the scavenging of superoxide radical with the IC50 Conclusion: All these results suggested that, formononetin is a good natural antioxidant which is capable of scavenging almost all types of free radicals. So this could be used to treat various diseases like diabetes, atherosclerosis, cancers, the aging and cardiovascular disease which is being caused by free radicals.value of 4.27 μg/ml. Superoxide inhibitory activity of formononetin was 5.3 %less than the standard quercetin.

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“…It is also used as a sexual stimulant (Pharmacopoeia Commission of China ). The hydroalcoholic extract of AO showed moderate potent antimicrobial and antifungal activity against many microorganisms (Srividya and others ). AO exhibited strong antioxidative capability against the autoxidation of methyl linoleate in bulk phase (Ly and others ).…”

Section: Introductionmentioning

confidence: 99%

Integrated Process for Production of Galangal Acetate, the “Wasabi‐Like” Spicy Compound, and Analysis of Essential Oils of Rhizoma Alpinia officinarum (Hance) Farw

Shen

Yeh

et al. 2016

Journal of Food Science

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Rhizoma Alpinia officinarum (Hance) Farw, Zingiberaceae (AO), a ginger family herb exhibiting stimulant and a carminative bioactivity, is widely used in European and Asian countries as spicy condiment and medicinal uses. Allyl isothiocyanate (AITC) is the main pungent taste of native Wasabi (Wasabia japonica). The cytotoxicity of AITC has been implicated in thymus, adrenals, and white blood cells. Considering food safety, apparently a safer substitute for wasabi is worthy commercialized. Previously, we found AO crude paste to be rather feasible for use as a "Wasabi-substitute" in fresh meat and cold salads. A process linking cold ethyl acetate (EtAc) extraction with silica gel adsorption and reversed phase high-performance liquid chromatography (RP-HPLC) (mobile phase, 75% methanol) was used to isolate galangal acetate, the Wasabi-like taste constituent. AO contained abundant galangal acetate (3.84 ± 0.07%) compared to A. galangal (0.57 ± 0.16%), and as already confirmed by thin layer chromatography (TLC), gas chromatography (GC)/mass spectrometry (MS)/MS and Nuclear Magnetic Resonance Spectroscopy (NMR), galangal acetate was particularly thermally labile. The steam distilled essential oil (SDEO) of AO (0.14% on wet basis) contained 80 compounds (number of component, %): monoterpene hydrocarbon (21, 13.83%); oxygenated monoterpene (17, 27.08%); sesquiterpene hydrocarbon (20, 31.03%), and oxygenated sesquiterpene (20, 21.85%), respectively. However, no spicy wasabi-like constituent remained in SDEO. Alternatively, n-hexane, EtAc, and methanol extracts of AO all showed potent DPPH- and superoxide anion-scavenging activity. Conclusively, SDEO although contains 80 volatiles, galangal acetate is absent due to thermal instability. Galangal acetate exhibits pleasant "Wasabi-like taste" for which we have successively developed an integrated process for mass production.

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Antioxidant and antimicrobial activity ofalpinia officinarum

Cited by 70 publications

References 6 publications

Composição química e eficácia do óleo essencial e do extrato etanólico de Alpinia zerumbet sobre Staphylococcus aureus

Composição química e eficácia do óleo essencial e do extrato etanólico de Alpinia zerumbet sobre Staphylococcus aureus

Study of Antioxidant Activity of Formononetin by in Vitro Method

Integrated Process for Production of Galangal Acetate, the “Wasabi‐Like” Spicy Compound, and Analysis of Essential Oils of Rhizoma Alpinia officinarum (Hance) Farw

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