Antioxidant activity, antibacterial and inhibitory effect of intestinal disaccharidases of extracts obtained from Eugenia uniflora L. Seeds

Abstract

The use of medicinal plants for disease prevention, treatment and cure is an ancient practice used by humanity, and many plants species are used in bioprospecting research. In this context, its stands out Eugenia uniflora L., populary known as pitangueira and belongs to the Myrtaceae family, with a wide geographic distribution and native of Brazil. In view of the therapeutic qualities of the plant and the lack of the studies on its seeds, the present study had as objective to evaluate the phytochemical profile of the extracts of Eugenia uniflora L. seeds, from different solvents, as well as their antibacterial activity, antioxidant and its inhibitory effect of intestinal disaccharidases. Results showed a high content of phenolic compounds and total flavonoids, thus characterizing antioxidant activity, also highlighting the best bacteriostatic action for the Gram positive strain of Staphylococcus aureus in the ethanolic fraction. Regarding the disaccharidases, a strong inhibitory action was observed for all concentrations, evidencing a antihyperglycemic potential. The present research allowed to concluded that Eugenia uniflora L. seeds have promising biological activities for the industrial sector, but a more detailed investigation is needed regarding their bioactive compounds.

Phenolic compound and fatty acid properties of some microalgae species isolated from Erbil City

“…The Ethanol extracts of species of red algae Callophyllis japonica (Kang et al, 2005) and Gracilaria tenuistipitata (Yang et al, 2012) shows antioxidant effects. Studies of an aqueous extract were examined with cell line which showed the recovery and enhanced of these cells from H 2 O 2 -induced DNA damage, counteracts cellular proliferation, and induced G2/M arrest that treatment of G. tenuistipitata (Yang et al, 2012;Lazzarotto-Figueiró et al, 2021). The discovery of novel fatty acids (FAs) with a wide range of new functions groups the study of fatty acid profiles as well as the presence of (FAs) in various lipid classes in microalgae is a new topic that promises to reveal a lot specially during their stationary phase in time producing and accumulate oil as carbon source, changes in fatty acid profiles under certain circumstances occur when microalgae try to acclimatize under unfavorable conditions (Wan Afifudeen et al, 2021).…”

Antibacterial activity of medicinal plants against Streptococcus agalactiae

“…It is the most reliable technique to determine substance antimicrobial properties. In Brazil, Lazzarotto-Figueiró et al (2021) reported a MIC value of 0.87 mg.mL -1 for the ethanolic extract of Eugenia uniflora L. leaves when testing against Staphylococcus aureus strains. They obtained higher MIC values when testing with Gramnegative bacilli (5 mg.mL -1 for Escherichia coli, 20 mg.mL -1 for Pseudomonas aeruginosa, and 10 mg.mL -1 for Salmonella typhymurium).…”

Antimicrobial, antioxidant activity and phytochemical prospection of Eugenia involucrata DC. leaf extracts

“…This genus is quite interesting from a chemical and pharmacological point of view and stands out for its therapeutic potential. Studies with species of this genus have shown promising results, such as antioxidant (Moresco et al, 2016) anti-inflammatory (Infante et al, 2016), antiviral (Sood et al, 2012), antibacterial (Simonetti at al., 2016;Lazzarotto-Figueiró et al, 2021) and hypoglycemic (Sharma et al, 2008).…”

“…The assays were performed according to the broth microdilution methodology described by (Weber et al, 2014), with modifications. The E. involucrata plant extracts to obtain high value chemical products (Andrade et al, 2009;Oliveira et al, 2012;Lazzarotto-Figueiró et al, 2021).…”