Antioxidant activity and phenolic content of ginger (Zingiber officinale Roscoe) combination with cinnamon (Cinnamomum burmanii) and Sappan wood (Caesalpinia sappan) as an anti-diabetic

Abstract

Based on IDF 6.7 million people deaths due to diabetes mellitus in 2021. Current study showed that dietary of fruits and vegetables containing antioxidant have associated with the reduction of the risk of many chronic diseases such as diabetes and cardiovascular. Plant phenolic compounds can act as antioxidant individually or in combination. Zingiber officinale Roscoe, Caesalpinia sappan, and Cinnamomum burmannii have phenolic compounds. However less information about antioxidant activity of ginger in this combination especially in decoction extraction method. This research was descriptive quantitative and aim at determining the content of phenolic compound and antioxidant activity of three varieties of ginger (Zingiber officinale Roscoe) combination with Cinnamomum burmannii and Caesalpinia sappan in decoction extraction method. Phenolic compound test was conducted by utilizing Folin-Ciocalteu method; while antioxidant activity test was performed by DPPH method. Both tests used Spectrophotometer UV-Vis. Based on ANAVA and independent t test combination of three varieties of ginger have higher total phenolic (38.80±0.217, 39.34 ± 1.02, 39.99± 0.44) than of non-combination (21.222±0.25, 21.36±0.60, 23.58±1.02). Three varieties of ginger combination have antioxidant activity higher (75.64 %, 68,97 %, 61,45 %) than ginger without combination (68.39 %, 60.29 %, 51.55%). Conclusion of this research is total phenolic content and antioxidant activity of ginger combination higher than in non-combined ginger, therefore ginger combination can be antidiabetic candidate.

Combination of polyherbal Phyllanthus reticulatus with Zingiber officinale and Cymbopogon citratus to optimize the antioxidant capacity

“…The analgesic and anti-inflammatory activity of a combination of Phyllanthus reticulatus and Mimosa pigra (Akhter et al, 2018). A study of the three species of Z. officinale with Cinnamomum burmannii and Caesalpinia sappan showed that the combination of ginger had either higher total phenolic or antioxidant activity than the non-combination (Mahmudati et al, 2022). Study on a combination of herbs, named Trikatuk, in many combinations, resulting in most of the combinations investigated in the present study also exhibiting additive or synergistic effects (Nutmakul & Chewchinda, 2023).…”