Antioxidant activities and oxidative stress inhibitory effects of ethanol extracts from Cornus officinalis on raw 264.7 cells

Hwang, Kyung‐A; Hwang, Yu-Jin; Song, Jinghui

doi:10.1186/s12906-016-1172-3

Cited by 62 publications

(46 citation statements)

References 37 publications

(29 reference statements)

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“…The inhibition of ROS is related to their structure, the number and orientation of the hydroxyl group and the antioxidant potential of each compound; employing in its ability to permeate cell membrane and modulate the pathway signaling of NADPH-oxidase, phospholipase D, protein kinase C-(PKC) alpha, among others 73 . Plant extract compounds can also increase the expression of genes associated with the antioxidative system, such Cu/Zn-SOD, Mn-SOD, catalase, and GPx genes, suppressing oxidative stress by increasing antioxidant activity of enzymes 74 .…”

Section: Chlorophyll Quantification Leaves Ofmentioning

confidence: 99%

Phytochemical analysis and biological activities of in vitro cultured Nidularium procerum, a bromeliad vulnerable to extinction

Gollo

Tanobe

Pereira

et al. 2020

Sci Rep

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In this study, Response surface methodology (RSM) was applied to optimize the yield of crude methanolic extract of Mitragyna speciosa leaves using Ultrasound-assisted extraction (UAE). The crude methanolic extract and its fractions were quanti ed in terms of total phenolic content and total avonoid content, along with characterized using Fourier-transform infrared and Gas chromatography-mass spectrometry. The results showed the maximum yield of 49.72% at the optimal conditions (temperature, 34 °C; time, 25 min; and volume of solvent, 166 mL). The recovery crude methanolic extract for TPC and TFC were 137.3 ± 15.7 mg GAE/g and 90.3 ± 15.3 mg RE/g, respectively.

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Section: Chlorophyll Quantification Leaves Ofmentioning

confidence: 99%

Phytochemical analysis and biological activities of in vitro cultured Nidularium procerum, a bromeliad vulnerable to extinction

Gollo

Tanobe

Pereira

et al. 2020

Sci Rep

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“…Thus, both antioxidants content and antioxidant capacity of dogwoods fruits are factors determining the quality of cultivars and basic physicochemical properties. In vitro assays such as free radical scavenging with DPPH (2,2-diphenyl-1-picrylhydrazyl radical), ferric ion reducing antioxidant power (FRAP), total antioxidant capacity with ABTS + (2,2-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) radical cation) and oxygen radical absorbance capacity (ORAC) were the most frequently used methods in a wide range of studies on C. mas (Dragović-Uzelac et al, 2007; Pantelidis et al, 2007; Hamid et al, 2011; Celep et al, 2012; Popović et al, 2012; Gunduz et al, 2013; Pyrkosz-Biardzka et al, 2014; Stankovic et al, 2014; Milenković-Andjelković et al, 2015; Hosu et al, 2016; Moldovan et al, 2016) and C. officinalis (Lee et al, 2006; West et al, 2012a; Hwang et al, 2016). Moreover, the hydromethanolic extracts of some cornelian cherry fruit cultivars from Turkey demonstrated significant H 2 O 2 scavenging activity (79.1%; Ersoy et al, 2011).…”

Section: Similarities and Differences Of Pharmacological Effects Or Bmentioning

confidence: 99%

Cornus mas and Cornus Officinalis—Analogies and Differences of Two Medicinal Plants Traditionally Used

Czerwińska

Melzig

2018

Front. Pharmacol.

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Among 65 species belonging to the genus Cornus only two, Cornus mas L. and Cornus officinalis Sieb. et Zucc. (Cornaceae), have been traditionally used since ancient times. Cornus mas (cornelian cherry) is native to southern Europe and southwest Asia, whereas C. officinalis (Asiatic dogwood, cornel dogwood) is a deciduous tree distributed in eastern Asia, mainly in China, as well as Korea and Japan. Based on the different geographic distribution of the closely related species but clearly distinct taxa, the ethnopharmacological use of C. mas and C. officinalis seems to be independently originated. Many reports on the quality of C. mas fruits were performed due to their value as edible fruits, and few reports compared their physicochemical properties with other edible fruits. However, the detailed phytochemical profiles of C. mas and C. officinalis, in particular fruits, have never been compared. The aim of this review was highlighting the similarities and differences of phytochemicals found in fruits of C. mas and C. officinalis in relation to their biological effects as well as compare the therapeutic use of fruits from both traditional species. The fruits of C. mas and C. officinalis are characterized by the presence of secondary metabolites, in particular iridoids, anthocyanins, phenolic acids and flavonoids. However, much more not widely known iridoids, such as morroniside, as well as tannins were detected particularly in fruits of C. officinalis. The referred studies of biological activity of both species indicate their antidiabetic and hepatoprotective properties. Based on the available reports antihyperlipidemic and anticoagulant activity seems to be unique for extracts of C. mas fruits, whereas antiosteoporotic and immunomodulatory activities were assigned to preparations of C. officinalis fruits. In conclusion, the comparison of phytochemical composition of fruits from both species revealed a wide range of similarities as well as some constituents unique for cornelian cherry or Asiatic dogwood. Thus, these phytochemicals are considered the important factor determining the biological activity and justifying the use of C. mas and C. officinalis in the traditional European and Asiatic medicine.

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“…8) Recently, antioxidant, anti-inflammatory, and hypoglycemic activity of the extract of C. officinalis fruits have been reported. [9][10][11] Loganin is an iridoid glycoside and known as a representative compound of C. officinalis fruits ( Fig. 1).…”

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confidence: 99%

Variation of loganin content in Cornus officinalis fruits at different extraction conditions and maturation stages

Ahn

et al. 2017

Bioscience, Biotechnology, and Biochemistry

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Efficient preparation of loganin from Cornus officinalis fruits was investigated. First, effect of extraction conditions on loganin yield was measured. The loganin content in C. officinalis extract was greatly affected by ethanol concentration and extraction time whereas extraction temperature exerted relatively little effect. Response surface methodology with Box-Behnken design suggested optimized extraction condition for maximum loganin yield as ethanol concentration, 32.0%; temperature 46.2 °C and extraction time, 46.7 min, which yielded 10.4 μg loganin/mg dried fruit. Next, the effect of maturation stage of C. officinalis fruits on loganin content was investigated. The loganin content in the extract of C. officinalis fruits was decreased as the maturation process. The loganin content in the unripe fruits was 18.0 μg/mg extract whereas reduced to 13.3 μg/mg extract for ripe fruits. Taken together, our present study suggested the importance of extraction condition and maturation stages for efficient preparation of loganin from C. officinalis fruits.

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Antioxidant activities and oxidative stress inhibitory effects of ethanol extracts from Cornus officinalis on raw 264.7 cells

Cited by 62 publications

References 37 publications

Phytochemical analysis and biological activities of in vitro cultured Nidularium procerum, a bromeliad vulnerable to extinction

Phytochemical analysis and biological activities of in vitro cultured Nidularium procerum, a bromeliad vulnerable to extinction

Cornus mas and Cornus Officinalis—Analogies and Differences of Two Medicinal Plants Traditionally Used

Variation of loganin content in Cornus officinalis fruits at different extraction conditions and maturation stages

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