Antimicrobial Potential and Phytochemical Investigation of Fixed Oil of Plant Chenopodium ambrosioides Linn.

Abstract

Globally infectious diseases are among the factors underlying deaths and are associated with approximately one-half of all mortalities in tropical countries. New, more effective and yet safe therapeutic agents are critical issues to manage challenging infectious diseases 1,2. Poor communities especially belonging to small isolated villages and native people in developing countries mainly use folk medicine for treatment of infectious diseases 2. Medicinal plants are consumed as decoctions, teas and juice preparations to treat respiratory infections or as a poultice and applied directly on the infected wounds or burns 1,2. So far extensive work has been done and still going on for the search of bioactive compounds to treat microbial infections as more effective and safer therapeutic agents. Chenopodium ambrosioides is an important medicinal plant widely used in the traditional medicine system in Europe, Asia, North and South America. It is a member of family, Chenopodiaceae. This plant is widely distributed in Baluchistan,

Extraction of essential oil from inflorescences of Dysphania ambrosioides and its activity against Botrytis cinerea

“…The major compounds found in the essential oil of D. ambrosioides are p-cymene, carvacrol, isoascaridole and ascaridoles (Monzote et al, 2014;Ávila-Blanco et al, 2014). The ascaridoles are mainly responsible for its activity against fungi, including plant pathogens (Jardim et al, 2008;Zabka et al, 2009;Nisar et al, 2013). The development of natural fungicides with ascaridoles is encouraging due to its broad range of activity against several plant pathogens (Jardim et al, 2008).…”

Antibacterial and antifungal activities of the crude extracts from the stem of Chenopodium ambrosioides Linn., an indiginous medicinal plant

“…The antibacterial activity was checked by the agar well diffusion method (Nisar et al, 2010(Nisar et al, , 2013. The solid nutrient agar was prepared by dissolving 28 g nutrient agar in distilled water and making the solution up to 1 ml.…”

“…The antifungal activity was determined by the agar well diffusion method (Nisar et al, 2010(Nisar et al, , 2013. In this method, Sabouraud dextrose agar (SDA) was prepared by mixing and dissolving mycological peptone, 10 g, glucose, 40 g, agar 15 g in approximately 900 ml of deionized water while the pH was maintained at 5.6 with hydrochloric acid and the total solution was made up to 1 L. The mixture was heated for at least 10 min and was then sterilized in autoclave at 121°C and 15 lb/in 2 pressure for a total of 15 min.…”

Antimicrobial studies of the crude extracts from the roots of Chenopodium ambrosioides Linn.

“…The antifungal activity was determined by the Agar Well Diffusion Method (Nisar et al, 2011;Nisar et al, 2013). In this method, Miconazole was used as the standard drug.…”

“…Chenopodium Ambrosioides Linn, being a therapeutic plant, is widely used in the traditional medicinal system in Asia, Europe and America especially as an antihelmintic agent and as a remedy for parasitic disorders (Monzote et al, 2009;Gadano et al, 2002). In Pakistan, the plant is widely distributed in Peshawar, Baluchistan, Dir, Swat, Kohala, Kashmir and Rawalpindi (Nasir et al, 1972;Nisar et al, 2013). This plant is a member of an important plant family, Chenopodiaceae, which have an elevated importance for phytochemical investigation and medicinal evaluation.…”