Antimicrobial Drug Resistance in Singapore Hospitals

Hsu, Li Yang; Tan, Thean-Yen; Jureen, Roland; Koh, Tse-Hsien; Krishnan, Prabha; Lin, Raymond Tzer‐Pin; Tee, Nancy Wen Sim; Tambyah, Paul Ananth

doi:10.3201/eid1312.070299

Cited by 87 publications

(77 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The first VRE strain isolated in Singapore was obtained in 1994 from a patient at the Singapore National Burns Centre (72). Two consecutive outbreaks followed later, in 2004 (73) and 2005 (74). According to the Network for Antimicrobial Resistance Surveillance in Singapore in 2006, VRE constitutes 0.8% of all enterococcal isolates in Singapore public hospitals (75).…”

Section: Use Of Antimicrobials In Hospitals and Antimicrobial Resistancementioning

confidence: 99%

Public Health Risks of Multiple-Drug-Resistant Enterococcus spp. in Southeast Asia

Daniel

Lee

Dykes

et al. 2015

Appl Environ Microbiol

View full text Add to dashboard Cite

Enterococci rank as one of the leading causes of nosocomial infections, such as urinary tract infections, surgical wound infections, and endocarditis, in humans. These infections can be hard to treat because of the rising incidence of antibiotic resistance. Enterococci inhabiting nonhuman reservoirs appear to play a critical role in the acquisition and dissemination of antibiotic resistance determinants. The spread of antibiotic resistance has become a major concern in both human and veterinary medicine, especially in Southeast Asia, where many developing countries have poor legislation and regulations to control the supply and excessive use of antimicrobials. This review addresses the occurrence of antibiotic-resistant enterococci in Association of Southeast Asian Nations countries and proposes infection control measures that should be applied to limit the spread of multipledrug-resistant enterococci.

show abstract

Section: Use Of Antimicrobials In Hospitals and Antimicrobial Resistancementioning

confidence: 99%

Public Health Risks of Multiple-Drug-Resistant Enterococcus spp. in Southeast Asia

Daniel

Lee

Dykes

et al. 2015

Appl Environ Microbiol

View full text Add to dashboard Cite

show abstract

“…A clear ring or zone of inhibition is seen around the water indicating poor growth if the bacteria are sensitive to antibiotics [6,9]. Antibiotic resistance involve naturally via natural selection acting upon random mutation [10].…”

Section: Introductionmentioning

confidence: 99%

Antibiotic Sensitivity Pattern of Bacteria from Selected Hospitals in Akungba Akoko, Ondo State, Southwest Nigeria

Olowokere¹

2013

IOSR-JPBS

View full text Add to dashboard Cite

“…Punta de catéter (2) : agar sangre (método Maki). Aspirados bronquiales (3) : agar sangre, Mac Conkey y manitol salado. Hemocultivo (1) : sistema automatizado BACTEC FX, con positividad a las 12 horas y sembrado posteriormente en agar sangre y Mac Conkey.…”

Section: Cultivos Bacterianos Determinación De Producción De Beta-launclassified

“…Actualmente, la emergencia de enterobacterias productoras de carbapenemasas (CPE) en el ámbito hospitalario, representa un verdadero problema de salud pública mundial, especialmente cuando se hace referencia a la Nueva Delhi Metalo beta-lactamasa (NDM) (1)(2)(3)(4) . El subtipo más frecuente de esta enzima es la NDM-1, codificada por el gen de origen plasmídico blaNDM-1.…”

Section: Introductionunclassified

Klebsiella pneumoniae nueva Delhi metalo-betalactamasa en el hospital nacional Dos de Mayo. Lima, Perú

Resurrección-Delgado

Montenegro-Idrogo

Chiappe-Gonzalez

et al. 2017

Rev Peru Med Exp Salud Publica

View full text Add to dashboard Cite

RESUMENLa emergencia de enterobacterias productoras de carbapenemasas de tipo Nueva Delhi Metalo beta-lactamasas (NDM), representan, hoy en día, un verdadero problema de salud pública mundial. La presencia de este mecanismo de resistencia limita o anula las opciones terapéuticas para combatir a estas bacterias. En Latinoamérica, las cifras son cada vez más elevadas, pues se reportan en Guatemala, Colombia, Chile, Argentina, entre otros. Perú no ha descrito, hasta la fecha, la presencia de este patrón de resistencia; sin embargo, desde hace varios años se presume de su existencia. Se describen nueve casos de Klebsiella pneumoniae NDM, como agentes infecciosos o colonizantes, en pacientes críticamente enfermos, en su mayoría con patología neuroquirúrgica, del Hospital Nacional Dos de Mayo, en Lima -Perú. Los pacientes de la serie descrita a continuación, representan los primeros reportes de Klebsiella pneumoniae NDM en el Perú. Palabras clave: Klebsiella pneumoniae, Nueva Delhi Metalo beta-lactamasa, Enterobacteriaceae, carbapenemasa, Latinoamérica. (fuente: DeCS BIREME). Klebsiella pneumoniae NEW DELHI METALO-LACTAMASE IN A PERUVIAN NATIONAL HOSPITAL ABSTRACTThe emergence of Enterobacteria producing carbapenemases of type New Delhi Metalo beta-lactamases (NDM), represent, today, a real problem of world public health. The presence of this resistance mechanism limits or nullifies the therapeutic options to combat these bacteria. In Latin America, the figures are getting higher, as they are reported in Guatemala, Colombia, Chile, Argentina, among others. Peru has not, to date, described the presence of this resistance pattern; however for several years it has been presumed to exist. Nine cases of Klebsiella pneumoniae NDM are described, as infectious or colonizing agents, in critically ill patients, mostly with neurosurgical pathology, of Hospital Nacional Dos de Mayo in Lima -Peru. The patients in the series described below represent the first reports of Klebsiella pneumoniae NDM in Peru.

show abstract

Antimicrobial Drug Resistance in Singapore Hospitals

Cited by 87 publications

References 6 publications

Public Health Risks of Multiple-Drug-Resistant Enterococcus spp. in Southeast Asia

Public Health Risks of Multiple-Drug-Resistant Enterococcus spp. in Southeast Asia

Antibiotic Sensitivity Pattern of Bacteria from Selected Hospitals in Akungba Akoko, Ondo State, Southwest Nigeria

Klebsiella pneumoniae nueva Delhi metalo-betalactamasa en el hospital nacional Dos de Mayo. Lima, Perú

Contact Info

Product

Resources

About