Antimicrobial activity of the crude ethanol extract from<i>Hyptidendron canum</i>leaves

Fiuza, Tatiana de Sousa; Sabóia‐Morais, Simone Maria Teixeira de; Paula, José Realino de; Tresvenzol, Leonice Manrique Faustino; Pimenta, Fabiana Cristina

doi:10.1080/13880200902917057

Cited by 7 publications

(4 citation statements)

References 14 publications

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“…The ripe fruit contains around calcium (9 mg), phosphorus (11 mg), carotene (1200–2000 IU), and ascorbic acid (20–30 mg) but is low in iron (0.2 mg) [83]. The phytochemical screening showed the presence of phenolics eugeniflorin D1 and eugeniflorin D2, tannins, triterpenes, heterosides, anthraquinones, flavonoids, and saponins [66].…”

Section: The Renaissance Of Food Plants As Therapeutic Agentsmentioning

confidence: 99%

The Therapeutic Potential of Medicinal Foods

Ramalingum

Mahomoodally

2014

Advances in Pharmacological Sciences

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Pharmaceutical and nutritional sciences have recently witnessed a bloom in the scientific literature geared towards the use of food plants for their diversified health benefits and potential clinical applications. Health professionals now recognize that a synergism of drug therapy and nutrition might confer optimum outcomes in the fight against diseases. The prophylactic benefits of food plants are being investigated for potential use as novel medicinal remedies due to the presence of pharmacologically active compounds. Although the availability of scientific data is rapidly growing, there is still a paucity of updated compilation of data and concerns about the rationale of these health-foods still persist in the literature. This paper attempts to congregate the nutritional value, phytochemical composition, traditional uses, in vitro and in vivo studies of 10 common medicinal food plants used against chronic noncommunicable and infectious diseases. Food plants included were based on the criteria that they are consumed as a common food in a typical diet as either fruit or vegetable for their nutritive value but have also other parts which are in common use in folk medicine. The potential challenges of incorporating these medicinal foods in the diet which offers prospective opportunities for future drug development are also discussed.

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Section: The Renaissance Of Food Plants As Therapeutic Agentsmentioning

confidence: 99%

The Therapeutic Potential of Medicinal Foods

Ramalingum

Mahomoodally

2014

Advances in Pharmacological Sciences

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“…To the authors' knowledge, there is no previous study on the anti-biofilm activity of these plants. These activities could be due to the presence of tannins, steroids, triterpenes, flavonoid glucosides, saponins and anthraquinones in the E. uniflora extracts as has been suggested previously (Fiúza et al, 2008;Lorenzi and Matos, 2002). The presence of these components could act individually or in combination to produce the effects observed at the respective concentrations.…”

Section: Discussionmentioning

confidence: 92%

Anti-candida biofilm properties of Cameroonian plant extracts

Elisabeth¹,

Lopez²,

Soto³

et al. 2016

J. Med. Plants Res.

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Candida infections can be superficial, invasive or disseminating. The virulence of Candida species has been attributed to several factors, including the promotion of hyphae and biofilm formation, adherence to host tissues, and response to environmental changes and morphogenesis. Resistance to many clinically used antifungal agents has led to the need to identify new compounds and drugs for therapeutic use. Therefore, the objective of this study was to evaluate the anti-candida and anti-biofilm activities of some Cameroonian plant extracts against Candida albicans and Candida glabrata. The biofilm biomass of C. albicans and C. glabrata was quantified using the violet crystal protocol. A microbroth dilution method was used to determine the minimum inhibitory concentrations (MICs), and a biofilm enumeration assay was employed to determine the minimum biofilm inhibition concentrations (MBICs) and minimum biofilm eradication concentrations (MBECs) of the extracts. The absorbance value of the biofilm biomass of C. albicans was 0.14±0.01 and that of C. glabrata was 0.51±0.06. Eugenia uniflora and Terminalia mantaly aqueous leaf extracts showed MICs of 0.3125 and 0.625 mg/mL for C. glabrata, while the MICs for C. albicans were 10 and 0.625 mg/mL, respectively. The MBIC and MBEC of C. glabrata of E. uniflora aqueous leaf extracts were 0.125 and 0.5 mg/mL, respectively, and 0.45 and >1.8 mg/mL, respectively for T. mantaly. The results of this study demonstrated the in vitro anti-biofilm potential of T. mantaly and E. uniflora aqueous leaf extracts against Candida biofilm. Nonetheless, further analyses of a larger number of Candida isolates and plant extracts are needed to validate these findings.

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“…These results agree with those found in the literature for different Eugenia species, such as Eugenia umbeliflora (Machado et al, 2005), Eugenia pyriformis (Souza et al, 2014), Eugenia brejoensis (Azevedo et al, 2012) and Eugenia brasiliensis (Magina et al, 2012). It is also worth noting that the methanolic extract of Eugenia uniflora leaves has a high inhibition for both Gram positive and Gram negative bacteria (10-156 μg/mL) (Bouzada et al, 2009) and ethanolic extract with MIC (S. aureus, S epidermidis, B. subtilis, E. coli, and P. aerugionosa) (Fiúza et al, 2009). However, data on the antimicrobial potential of E. involucrata extracts were not verified in the literature; this is the first report on the antimicrobial potential of this species.…”

Section: Antimicrobial Activitymentioning

confidence: 99%

Antimicrobial, antioxidant activity and phytochemical prospection of Eugenia involucrata DC. leaf extracts

et al. 2023

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The species Eugenia involucrata DC. is a plant native to Brazil and is traditionally used for intestinal problems, however, little research has documented about its biological potential and phytochemical profile. Thus, the objective of this study was to carry out preliminary phytochemical prospecting, antimicrobial and antioxidant potential of E. involucrata extracts. Using the E. involucrata leaves, aqueous and organic extracts were obtained using the following solvents (ethanol, methanol, hexane, acetone, dichloromethane and ethyl acetate). The phytochemical prospecting detected the presence of saponins, steroids, flavonoids and tannins in the extracts. Ethanolic and methanolic extracts presented antimicrobial activity for most of the bacterial strains tested, as well as for yeast Candida albicans, with concentrations between 3.12 and 50 mg/mL. The ethanolic and metanolic extract presented high free radical sequestration potential (>90%). The methanol extract showed an IC50 value statistically equal to that found for the commercial antioxidant BHT (p <0.05). The crude extracts obtained with ethanol and methanol were the most promising. These results suggest that methanolic, ethanolic and aqueous extracts are a promising source of natural bioactive.

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Antimicrobial activity of the crude ethanol extract fromHyptidendron canumleaves

Cited by 7 publications

References 14 publications

The Therapeutic Potential of Medicinal Foods

The Therapeutic Potential of Medicinal Foods

Anti-candida biofilm properties of Cameroonian plant extracts

Antimicrobial, antioxidant activity and phytochemical prospection of Eugenia involucrata DC. leaf extracts

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