Antimicrobial Activity of Some Medicinal Plant Extracts against Multidrug Resistant Bacteria

Masoumian, Majid; Zandi, Mohammad

doi:10.5812/zjrms.10080

Cited by 30 publications

(19 citation statements)

References 26 publications

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“…Many medicinal plant extracts have been known to possess antimicrobial effects. [36,37] Pomegranate peels possess novel biologically active compounds. The extracts from pomegranate peels have been reported to possess inhibition action against human.…”

Section: Resultsmentioning

confidence: 99%

Untitled

Al-Salman¹

2019

AJP

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• Extraction, isolation, and estimation of PNbb in pomegranate peels. • Use GC-mas technique to diagnose the PNbb extracted from pomegranate peels. • The study of the biological efficiency of compound PNbb against three types of clinical pathogenic. • Demonstrate the biologic activity of the extracted organic compound PNbb by finding the statistical values by finding the statistical values f the extracted organic com

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Section: Resultsmentioning

confidence: 99%

Untitled

Al-Salman¹

2019

AJP

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“…Sesquiterpenes lactones are potentially selective toward tumour and cancer stem cells by targeting speci ic signalling pathways, which make them lead compounds in cancer clinical trials (Zhang et al, 2005). Tomentosin showed antibacterial and antifungal effects (Masoumian and Zandi, 2017) and in vitro antiproliferative activity on various human cancer cell lines (Hegazy, 2015).…”

Section: Phytochemical Evaluationmentioning

confidence: 99%

Antitumor, Antimicrobial activities and Phytochemicals Constituent of different Extracts of Pulicaria undulata (Forssk.) Oliver. Grown Naturally in Saudi Arabia

Alshehr

Ghobashy

2020

ijrps

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Antitumor and antimicrobial resistance are a habitual global issue, which continually demands finding new natural compounds to encounter the resistance. Pulicaria undulata (Forssk.) Oliver. (Asteraceae family) has numerous promising medicinal properties. The recent work aimed at determination of antitumor effects of three extracts of P. undulata on three types of human carcinoma; HEPG-2 hepatocellular carcinoma, MCF-7 breast carcinoma and HCT-116 colon carcinoma cell lines. Anticancer activity was assessed through studying the viability of the cancer cells and apoptotic pathway. Also, antimicrobial potency of different extracts was assessed against studied human pathogens (five Gram negative bacteria, two Gram positive bacteria and yeast). The results reveal that chloroform extract has different levels of cytotoxicity toward the three types of cancer cell lines. A considerable decline in cancer cell rates has been linked to increasing in concentration of plant extract. The half maximal inhibitory concentration IC 50 value was 3.01 µg/ mL for the HepG-2, 16.4 µg/mL for the MCF-7, and 7.4 µg/ mL for HCT-116. Followed by the ethyl acetate extract which showed strong cytotoxic activity against HEPG2 with IC 50 = 12.2 µg ∕ml and moderate activities against MCF7 and HCT 116 and recorded (IC 50 = 26.7 and 26.4 µg ∕ml, respectively). While the crude methanol extract recorded the lowest cytotoxic effect against HEPG2, MCF7 and HCT 116 with (IC 50 = 51.4, 105.1 and 86.7 µg ∕ ml, respectively). Chloroform and ethyl acetate extracts have a high antimicrobial activity more than methanol extract against the pathogens being studied. HPLC and GCMs Analysis identified numerous chemical compounds of P. undulata extracts with various therapeutic benefits. In conclusion, P. undulata has the potential to act as an antimicrobial agent against various pathogenic microbes and is a promising wild herb for the treatment of cancer.

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“…Bu çalışmada yer alan stafilokok türlerinin birçoğu çoklu ilaç direncine sahip olup, H. atomarium Boiss. ekstraktlarına karşı hassasiyet göstermişlerdir [34].…”

Section: Bulgularunclassified

Antibacterial Effect of Hypericum atomarium Boiss. Extracts against Clinical Staphylococcus spp.

Önem

Çevikbaş

2018

Süleyman Demirel Üniversitesi Fen Edebiyat Fakültesi Fen Dergisi

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Özet: Hypericum atomarium Boiss, Hypericum cinsine ait çok yıllık bir bitki olup, geleneksel tedavi yöntemlerinde tedavi amacıyla kullanılmaktadır. Yapılan bu çalışma ile H. atomarium Boiss. çiçeklerinden hazırlanan metanol (MeOH), kloroform (CHCl3) ve su (H2O) eksraktlarının klinik Stafilokok izolatları (S. aureus, S. hominis, S. haemolyticus, S. epidermidis) üzerine antibakteriyel etkisi araştırılmıştır. Elde edilen sonuçlara göre hazırlanan tüm ekstraktların klinik izolatlar üzerinde yüksek oranlarda antibakteriyel etkiye sahip oldukları tespit edilmiştir. En fazla antibakteriyel etki kloroform ile hazırlanan ekstrakta (20,7 mm) tespit edilmiş olup tüm izolatlar değerlendirildiğinde inhibisyon değerlerinin 20,7-16 mm arasında olduğu tespit edilmiştir.

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Antimicrobial Activity of Some Medicinal Plant Extracts against Multidrug Resistant Bacteria

Cited by 30 publications

References 26 publications

Untitled

Untitled

Antitumor, Antimicrobial activities and Phytochemicals Constituent of different Extracts of Pulicaria undulata (Forssk.) Oliver. Grown Naturally in Saudi Arabia

Antibacterial Effect of Hypericum atomarium Boiss. Extracts against Clinical Staphylococcus spp.

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