Antimicrobial Activity of Sesquiterpenes from the Essential Oil ofJuniperus thuriferaWood

Abstract

Chemical analysis of the essential oil of Juniperus thurifera wood led to the identification of fifty-eight sesquiterpene compounds, of which twenty-eight have been isolated, two of them being new natural cedrane derivatives (1 and 2). Their structures were established on the basis of 1D NMR and 2D NMR spectra. The antimicrobial activities of different pure compounds of this oil were tested against nine microorganisms (Gram-positive and Gram-negative bacteria, and yeasts). Seven of the tested compounds exhibited a relevant activity, with the known alpha- and beta-cedrenes and sesquithuriferol showing minimum inhibitory concentrations of 3.06 microg/mL against Bacillus subtilis and Proteus sp.

Eco-friendly and Safe Role of Juniperus procera in Controlling of Fungal Growth and Secondary Metabolites

“…There was significant difference (P<0.01) among colony radius of A. flavus and F. oxysporum at different concentration of J. procera extract alone, J. procera extract with carbomar and carbomar alone and control. This confirms the antifungal activities exerted by juniper extracts against fungal mycelium [21,23,25]. Growth of A. flavus and F. oxysporum was decreased with increasing concentrations of J. procera extract (Figure 1B-D).…”

“…It is estimated that 70 species of Juniperus are distributed throughout the world [20]. Juniperus species have been extensively investigated as a source of natural products with potential antibacterial, antifungal and insecticidal activities [21][22][23][24][25]. J. procera is used locally to treat tuberculosis and jaundice [26], intestinal worms and eye infections (Klaus and Adala), its wood is resistant to termite and rot [27].…”

New Triterpene Glucosides from the Roots of Rosa laevigata Michx

“…The tests were carried out according to the protocols described in the literature [11]. K. pneumoniae , T. glabrata and C. neoformanin were obtained from Huashan Hospital, Shanghai, P. R. China.…”

Mystroxylon aethiopicum chloroform root bark extracts phytochemical analysis using gas chromatography mass spectrometry

“…Compounds that have been reported to exhibit antibacterial and antifungal activities are δ-cadinol, copaene, caryophyllene, α-calacorene, β-eudesmol, γ-cadinene, aromadendrene, thujopsene, α-cubebene, cyperene, α-curcumene, caryophyllene oxide, norelidol, farnesol, geranyl linalool, totarol, geranylgeraniol and borneol (Ho et al, 2011;Kubo et al, 1992;Pérez et al, 2011;Vukovic et al, 2008;Baskaran et al, 2016;Sarada et al, 2011;Rajeswari et al, 2011;Su and Ho, 2013;Solis et al, 2004;Krist et al, 2015;Sadashiva et al, 2010;Merghache et al, 2014;Manter and Kelsey, 2007;Barrero et al, 2005;Naidoo et al, 2009;Shaik et al, 2014;Mulyaningsih et al, 2010;Ghannadi et al, 2012). α-muurolene, isolongifolene, α-cubebene and (Z,Z)-α-farnesene have been reported to possess antioxidant activities (Gurbuz et al, 2013;Naidoo et al, 2009;Çelik, 2014;Rangasamy and Namasivayam, 2014).…”