Antimicrobial Activity and Chemical Composition Screening of Epilobium montanum Root

Abstract

Medical herbs have many bioactive component and they are used in microbial treatment since ancient time. The resistance of pathogen to antibiotic is became a critical problem, so novel antimicrobial agent related research is required. Epilobium montanum related antimicrobial research doesn't exist, therefore root of this medicinal plant investigation was applied against 17 bacteria and 1 fungi by using disk diffusion method. These microbial species include Bacillus, Enterobacter, Enterococcus, Escherichia, Klebsiella, Listeria, Pseudomonas, Salmonella, Staphylococcus and Candida genera. Besides, chemical composition of this sample was determined by Gas Chromatography-Mass Spectroscopy. The results were presented that E. montanum has antimicrobial activity against all tested microbial species except E. coli. Seventeen major chemical components were determined, but some composition of this sample is not match with library. For this reason, this medicinal plant contain unknown molecules and this molecules should be analysed by NMR spectra for 3D structure determination and identification.

In Vitro Human Skin Penetration, Antioxidant and Antimicrobial Activity of Ethanol-Water Extract of Fireweed (Epilobium angustifolium L.)

“…Seventeen major chemical components were identified by GC-MS in ethanol extracts of E. montanum by Canli et al, wherein a large group of identified compounds was fatty acids (palmitic acid and (Z,Z,Z) 9,12,15-octadecatrienoic acid). Other significant compounds of the extract observed by these authors were: γ-sitosterol, 1-heptacosanol, and 1,2,3-benzenetriol [ 36 ]. Several compounds belonging to the terpenes group, i.e., camphor and α- and β-caryophyllene oxide, were found in our study; they were also observed in E. hirsutum and E. angustifolium by others [ 35 , 37 ].…”

Chemical Composition and Antimicrobial Activities of Cold-Pressed Oils Obtained From Nettle, Radish and Pomegranate Seeds

“…For determination of the chemical composition of oil samples the methodology mentioned previously was used (Canlı, Yetgin, Akata & Altuner, 2017b).…”

Synthesis and Characterization of Some New Heteroaromatic Compounds Having Chirality Adjacent to a 1,3,4‐Thiadiazole Moiety and Their Antimicrobial Activities

“…The antimicrobial activity is determined using a disk diffusion method based on Andrews . Petri dishes with a diameter of 9 mm, which contained 25 mL of Mueller‐Hinton agar, were used in order to standardize the work, as described previously in several studies . The newly synthesized 1,3,4‐thiadiazole derivatives were dissolved in ethanol to a final concentration of 5 mg/mL.…”