Antimicrobial activities of secondary metabolites produced by endophytic fungi from Spondias mombin

Abstract

We performed a search for bioactive compounds produced by fungal endophytes from Spondias mombin (Anacardiaceae). Culture broth extracts of Guignardia sp., Phomopsis sp. and Pestalotiopsis guepinii were separated by chromatographic methods and tested for biological activities. The crude extracts of these endophytes were tested against fourteen organisms, including actinomycetes, Gram-negative and Gram-positive bacteria, yeast, and filamentous fungi. All fungal extracts inhibited actinomycete growth. Guignardia sp. was also active against Escherichia coli, Staphylococcus aureus, Saccharomyces cerevisiae, Geotrichum sp., and Penicillium canadensis. Culture extracts of P. guepinii were active against S. cerevisae, while strains of Phomopsis sp. showed a pronounced antifungal effect against Cladosporium elatum, Mycotypha sp. and S. cerevisae.

Genetic variation among Phyllosticta strains isolated from citrus in Florida that are pathogenic or nonpathogenic to citrus

“…The non-pathogenic Phyllosticta strains, including P. capitalensis, are typical endophytes (Baayen et al, 2002) that can have various beneficial properties like fending off insect pests and pathogens or producing medicinal metabolites and hydrolytic enzymes (Arnold et al, 2003;Kelemu et al, 2001;Mejía et al, 2008;Rakotoniriana et al, 2008;Rodrigues et al, 2000). Phyllosticta citricarpa might be suppressed by P. capitalensis in citrus tissues, because some P. capitalensis isolates outgrew P. citricarpa when compared in competition tests on agar plates (Baayen et al, 2002;Er et al, 2013a).…”

Phytochemical, antioxidant and microbial inhibitory effects of Spondias mombin leaf and stem bark extracts

“…Among these medicinal plants, Spondias mombin has been reported to have significant medicinal and economic values (1). The anti bacterial, antimicrobial, antiviral and anti fungal potentials of the plant have been reported (2,3,4,5). The plant was recommended for use by pregnant women after five months of pregnancy (6) while the mineral analysis of the plant has also been documented (7,8).…”

Medicinal and economic value of spondias mombin

“…The fruits decoction is drunk as a diuretic and febrifuge, the decoction of the bark and the leaves as emetic, antidiarrhoea and used in the treatment of dysentery, haemorrhoids, gonorrhoea and leukorrhea. The antimicrobial, antibacterial, antifungal, and the antiviral properties of Spondias mombin have been reported (Ajao et al, 1985;Verpoorte and Dihal, 1987;Abo et al, 1999;Corthout et al, 1991;Rodrigues and Hasse, 2000). A tea of the flowers and the leaves is taken to relieve stomach ache, various inflammatory conditions and wound healings (De Ferreyra, 1981;Jaramillo and Ahunada-Barona, 1983;and Villegas et al, 1997).…”