Medicinal and economic value of spondias mombin

Ayoka, Abiodun Oladele; Akomolafe, Rufus O.; ., O.S. Akinsomisoye; Ukponmwan, OE

doi:10.4314/ajbr.v11i2.50714

Cited by 67 publications

(82 citation statements)

References 12 publications

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“…The concoction from the leaves is widely used for the treatment of diarrhea, dysentery, stomach ache and inflammation (Ayoka et al 2008). Various studies have shown that the leaf extracts possess pharmacological properties such as anti-inflammatory, antimalaria, antibacterial, anxiolytic, antioxidant and antiviral effects (Ayoka et al 2008). Despite the ethnobotanical usage of the plants, no biological activity from its essential oil has been reported in literature to support this claim.…”

Section: Introductionmentioning

confidence: 94%

“…Other common names are Iyeye (Yoruba), ngulungwu (Igbo), pauda tapera (Brazil) and ubo (Peru). The concoction from the leaves is widely used for the treatment of diarrhea, dysentery, stomach ache and inflammation (Ayoka et al 2008). Various studies have shown that the leaf extracts possess pharmacological properties such as anti-inflammatory, antimalaria, antibacterial, anxiolytic, antioxidant and antiviral effects (Ayoka et al 2008).…”

Section: Introductionmentioning

confidence: 99%

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Identification and comparison of the volatile constituents of fresh and dried leaves ofSpondias mombinfound in North-central Nigeria:in vitroevaluation of their cytotoxic and antioxidant activities

Oladimeji

Aliyu

Ogundajo

et al. 2016

Pharmaceutical Biology

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Context:Various studies have shown that the leaf extracts of Spondias mombin Linn (Anacardiaceae) possess pharmacological properties such as antioxidant and antiviral effects. However, no biological activity from its essential oil has been reported in literature. Objective: To analyse the chemical constituents, cytotoxic activity and antioxidant capability of the essential oils from fresh and dried leaves of S. mombin. Materials and methods: Hydrodistillation using Clevenger-type apparatus was employed to obtain the essential oil. Oil analysis was performed using an HP 6890 Gas Chromatograph coupled with an HP 5973 Mass Selective Detector. The cytotoxicity bioassay was carried out using the brine shrimp lethality test (10,000-0.01 lg/mL). Additionally, the reactive oxygen species scavenging potential of the two S. mombin oils (1000-200 lg/mL) were investigated using a hydroxyl radical scavenging and ferric iron reducing system. Results: Chemical analysis of essential oils from S. mombin revealed the presence of 41 compounds, with predominance of monoterpenoids, sesquiterpenoids and non-terpenoids derivatives. In both fractions, the principal component was b-caryophellene (27.9-30.9%), followed by c-cadinene (9.7-12.3%). There was an increase in the oxygenated monoterpenoid contents and a concomitant decrease in the amounts of sesquiterpenoids hydrocarbons observed on drying the leaves. The oil obtained from the fresh leaves was more active than that obtained from dried leaves, with LC 50 values (from the brine shrimp lethality assay) of 0.01 and 4.78 lg/mL, respectively. The two oils (from fresh and dried leaves) at 1.0 mg/mL scavenged hydroxyl radical by 83% and 99.8%, respectively. Moreover, they reduced ferric ion significantly and compared favourably with vitamin C. Conclusions: Essential oil derived from the leaves of S. mombin could hold promise for future application in the treatment of cancer-related diseases. ARTICLE HISTORY

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Section: Introductionmentioning

confidence: 94%

Section: Introductionmentioning

confidence: 99%

Identification and comparison of the volatile constituents of fresh and dried leaves ofSpondias mombinfound in North-central Nigeria:in vitroevaluation of their cytotoxic and antioxidant activities

Oladimeji

Aliyu

Ogundajo

et al. 2016

Pharmaceutical Biology

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“…from the flowers and leaves) is taken to relieve stomach aches, biliousness, urethritis, cystitis, as well as to ameliorate inflammation of the eye and/or throat (Ayoka et al, 2008). Lastly, the decoction of the astringent bark has been used as an emetic, a remedy for diarrhea, dysentery, and hemorrhoids, and also as a treatment for gonorrhea (Ayoka et al, 2008).…”

Section: Introductionmentioning

confidence: 99%

“…Lastly, the decoction of the astringent bark has been used as an emetic, a remedy for diarrhea, dysentery, and hemorrhoids, and also as a treatment for gonorrhea (Ayoka et al, 2008).…”

Section: Introductionmentioning

confidence: 99%

The leaf extract ofSpondias mombinL. displays an anti-inflammatory effect and suppresses inducible formation of tumor necrosis factor-α and nitric oxide (NO)

Nworu

Akah

Okoye

et al. 2011

Journal of Immunotoxicology

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“…Vitamin A helps to maintain good sight and prevents eye diseases. Both the vitamins have antioxidant property [28]. Vitamin B (folic acid) were occurred in traces.…”

Section: Estimation Of Vitaminsmentioning

confidence: 99%

Pharmacognostic Standardisation of Cayratia Pedata (Lam.) Gagnep. Var. Glabra Gamble–an Endemic and Endangered Medicinal Climber in Thiashola, Nilgiris

Sharmila¹,

Kalaichelvi²,

Dhivya³

2017

Int J Pharm Pharm Sci

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Objective: The main objective was to develop a detailed pharmacognostic profile of aerial plant parts of Cayratia pedata (Lam.) Gagnep. var. glabra Gamble (Vitaceae) an endemic and endangered medicinal taxon distributed in Thiashola, Manjoor, Nilgiris South Division, Western Ghats.Methods: All pharmacognostic and phytochemical evaluation of Cayratia pedata var. glabra was carried out by different evaluation methods like macroscopic, microscopic, physicochemical, minerals, vitamins, heavy metal analysis, phytochemical studies and GC/MS analysis. Results:The macroscopical investigation revealed that the stem is hirsute and grows up to a height of 12 m. The leaves are alternate, oblong and acuminate with smooth surface and texture (3 to 6 cm). Tendril, leaf-opposed, branched, wiry and coiled. Flowers yellow and fruits bilobed. The anatomical study in tendril and old stem provides a set of characters specific for C. pedata var. glabra with which one can establish the identity of the plant in fragmentary form. The availability of macro and micro elements were studied in plant powder (ash). The macro elements, calcium (34.50 mg/100 g) and potassium (11.45 mg/100 g) were present in high amount likewise in microelements manganese (4.56 mg/100 g) was significantly higher. The fat-soluble vitamin A-retinol (156.8 iu) was present in higher amount when compared to other vitamins. Results of the heavy metal analysis revealed that the concentration of Lead was less than 1 ppm and chromium occurred in traces. The other heavy metals like mercury, cadmium and arsenic were totally absent. The percent yield was maximum in methanol extract (11%) followed by water extract (10%). The preliminary phytochemical screening revealed the presence of alkaloids, flavonoids, glycosides, phenols and tannins, steroids and sterols, triterpenoids and volatile oil. GC-MS analysis showed the presence of 15 compounds such as Heptadecane (17.36%), Silane, trichlorooctadecyl (17.29%), Eicosane (15.44%), Heptane,2,2,3,3,5,6,, n-Tetradecyltrichlorosilane (13.64%), Pentadecane (10.55%), Iron, tricarbonyl [N-(phenyl-2-pyridinylmethylene) benzenamine-N, N'] (10.91%) and Octadecane (8.93%) were the other major compounds present. Conclusion:The above parameters, which are being testimony for the first time, are momentous towards establishing the pharmacognostic profile for future identification and authentication of genuine plant material. This approach is important for this time since this species is listed in Red data book as per the IUCN red list categories and criteria due to their lower germination percentage and also due to its enriched medicinal value.

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Medicinal and economic value of spondias mombin

Cited by 67 publications

References 12 publications

Identification and comparison of the volatile constituents of fresh and dried leaves ofSpondias mombinfound in North-central Nigeria:in vitroevaluation of their cytotoxic and antioxidant activities

Identification and comparison of the volatile constituents of fresh and dried leaves ofSpondias mombinfound in North-central Nigeria:in vitroevaluation of their cytotoxic and antioxidant activities

The leaf extract ofSpondias mombinL. displays an anti-inflammatory effect and suppresses inducible formation of tumor necrosis factor-α and nitric oxide (NO)

Pharmacognostic Standardisation of Cayratia Pedata (Lam.) Gagnep. Var. Glabra Gamble–an Endemic and Endangered Medicinal Climber in Thiashola, Nilgiris

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