Antimicrobial Activities of Phragmanthera incana (schum.) Balle, a Mistletoe Species Harvested from Two Host Plants against Selected Pathogenic Microbes

Ogunmefun, O. T.; Ekundayo, Esther Aanuoluwa; Ogunnusi, TA; Olowoyeye, A; Fasola, T. R.; Saba, Adebowale Benard

doi:10.9734/arrb/2015/14947

Cited by 6 publications

(15 citation statements)

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“…Hence, the biocompounds are chiefly dependent on their host. This was evident in the antimicrobial works of Ogunmefun et al [ 5 ], Deeni and Sadiq [ 17 ], and Efuntoye et al [ 18 ] which showed different antimicrobial activities of the same plant on different hosts. This study in comparison to the works of Ogunmefun et al [ 5 ] showed that Phragmanthera capitata of rubber tree (Hevea brasiliensis) showed greater promise for its antibacterial potential (MIC of 1.25 mg/mL to 5 mg/mL in the organic solvents) than the ones harvested from kola nut and cocoa (MIC of 100 mg/mL to 200 mg/mL).…”

Section: Discussionmentioning

confidence: 95%

“…The bacteria and fungi used for this work were selected based on their roles as opportunistic pathogens to humans and animals and their association with stomach disorders, diarrhoea, dysentery, wound, and other infections and primarily to validate the ethnopharmacological claims of P. capitata as a remedy for these diseases [ 5 ].…”

Section: Methodsmentioning

confidence: 99%

“…Among the potential sources of new agents, plants have long been investigated owing to their popular use as remedies for diverse infectious diseases because they contain many bioactive compounds that could be of interest in therapeutics [ 3 ]. Herbal drugs research is increasing on a daily basis not only because they serve as lead to the formulation of new preventive or curative drugs, but also because they are affordable and believed to be safer than orthodox drugs [ 5 – 7 ].…”

Section: Introductionmentioning

confidence: 99%

“…As with most mistletoe, it is a medicinal plant which has been used in Africa traditional medicine for the treatment of diverse diseases [ 11 ]. It is a parasite of different economic plants like cocoa, kola, coffee, mango, almond, rubber tree, and so on [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

“…Prior to this study, there had been a dearth or no information on the antimicrobial activities of Phragmanthera capitata growing on rubber tree saving the report of Ogunmefun et al [ 5 ] of Phragmanthera incana growing on kola nut and cocoa. This may be due to the fact that most studies on mistletoe are focused on the destructive habit and physiological interaction on host plants.…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of the Antibacterial and Antifungal Properties of Phragmanthera capitata (Sprengel) Balle (Loranthaceae), a Mistletoe Growing on Rubber Tree, Using the Dilution Techniques

Ohikhena

Wintola

Afolayan

2017

The Scientific World Journal

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The alarming increase in multidrug resistance of pathogenic microorganisms to conventional drugs in recent years has prompted the search for new leads in alternative remedies in natural products. Hence, this study was aimed at evaluating the antimicrobial properties of Phragmanthera capitata, a parasitic mistletoe growing on rubber trees. The in vitro antimicrobial activities of the acetone, methanol, ethanol, and aqueous extracts were investigated using five gram-negative and five gram-positive bacteria and four fungi. A 96-well resazurin broth and agar dilution techniques were used for the determination of the Minimum Inhibitory and Bactericidal Concentrations. The antibacterial activity of the organic extracts had comparative effects on all the bacteria with a MIC of 1.25 to 5 mg/mL and MBC of 2.5 to 10 mg/mL. However, the acetone extract showed higher bactericidal effect while the aqueous extract was not active. The organic solvent extracts also showed antifungal activities on two of the fungi with a MIC of 1.25 mg/mL to 10 mg/mL. However, the aqueous extract had the highest activity inhibiting all the fungi with a MIC of ≤0.3125 to 1.25 mg/mL. The study supports the ethnomedicinal claims of P. capitata as a remedy for the diseases/infections caused by these organisms.

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Section: Discussionmentioning

confidence: 95%

Section: Methodsmentioning

confidence: 99%