Antimicrobial Activities of Cajanus cajan, Garcinia kola and Xylopia aethiopica on Pathogenic Microorganisms

Ezeifeka, G. O.; Michael, Orji; Mbata, T. I.; ., A.O. Patrick

doi:10.3923/biotech.2004.41.43

Cited by 26 publications

(2 citation statements)

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“…The seeds are used in the treatment of bronchitis, throat infections, colics, headaches, chest colds, coughs, diarrhoea, hepatitis, asthma and dysmenorrheal/menstrual cramps [32] . The seed has also shown broad spectrum antibacterial activities [33] . The result of this finding was also in consistency with the result reported by Ogbulie et al [34] on the antimicrobial efficacy of cold, hot water and ethanol extract of G. kola which revealed that cold and hot water extract of G. kola moderately inhibited the growth of Staphlococcus aureus and Streptococcus pyogenes with zone of inhibition of between 9-15mm.…”

Section: Discussionmentioning

confidence: 99%

In Vitro Antibacterial Activity and Phytochemical Screening of Garcinia Kola Extracts Against Methicillin Resistant Staphylococcus Aureus (MRSA)

Ali¹,

Zage²,

Ahmed³

et al. 2018

JPP

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Modern medicines have always depended on herbal extracts from plants as fundamental source of therapeutic ingredients. The aim of the study was to determine the phytochemical constituents and antibacterial activity of Garcinia kola seed extracts against clinical isolates of Methicillin Resistant Staphylococcus Aureus (MRSA). Total of 107 Staphylococcus isolates from infected wound and urine and were collected from Abubakar Imam Urology Center in Kano State, Nigeria over a period of eight months (October 2015 to May 2016). A disc diffusion method was used for characterization of MRSA. The phytochemical screening of the plant materials was done using conventional laboratory method while the antibacterial activity of the plant extracts was determined using agar well diffusion method. The result of bacterial characterization showed that eight isolates found were to be Methicillin Resistant Staphylococcus aureus (MRSA). Phytochemical screening of the seeds, leaves and stem bark extracts indicated the presence of Alkaloid, Tannin, Saponin, and Cardiac glycoside, Flavonoid, Terpenoid, Phenols Anthraquinone and Steroid. However, reducing sugar is absent. The antibacterial activity of the plant showed that the plant part extracts demonstrated antimicrobial effect against the test isolates with higher activity in seeds compared to leaves and stem. Statistical analysis of the result revealed that the overall average zone of inhibition shown by the extracts is 11.68 mm with methanolic seeds extract exerting the highest antibacterial effects on the test isolates with average zone of inhibition of 12.78 mm, followed by methanolic leaf extract 12.37 mm then aqueous seed extract with zone of inhibition of 11.87 mm. Least zones of inhibition were recorded in aqueous leaf extract and methanolic stem back extract with zones of inhibition of 11.28 and 10.43 mm respectively. The Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of the extracts range from 12.5 -100 mg/ml of the extracts. Findings from this work support the use of seed extracts from G. kola as medicinal plant.

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Section: Discussionmentioning

confidence: 99%

In Vitro Antibacterial Activity and Phytochemical Screening of Garcinia Kola Extracts Against Methicillin Resistant Staphylococcus Aureus (MRSA)

Ali¹,

Zage²,

Ahmed³

et al. 2018

JPP

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“…Many scientists have reported that microorganisms are the causal agents of food-borne diseases and food spoilage (8,9), which raises the necessity for anti-microbial agents (10). The anti-microbial properties of plants have been extensively investigated worldwide as they contain potent phytochemical constituents having antimicrobial properties (11).…”

Section: Introductionmentioning

confidence: 99%

In vitro anti-oxidant, anti-microbial and anti-inflammatory activities of five Indian cultivars of mango (Mangifera indica L.) fruit peel extracts

Umamahesh

Ramesh

Kumar

et al. 2019

J Herbmed Pharmacol

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Introduction: All parts of the mango plant contain secondary metabolites that possess several beneficial properties. In the present study, evaluation of in vitro anti-oxidant, anti-microbial and anti-inflammatory activities of five Indian cultivars of mango fruit peel extracts were carried out.Methods: Different solvent (hexane, ethyl acetate, and methanol) extracts of five Indian cultivars of mango fruit peels were prepared by using soxhalate, and the aqueous extract was prepared by maceration. In vitro anti-oxidant activities of these extracts were determined by using 2,2-Diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azinobis 3-ethylbenzothiazoline-6-sulfonic acid (ABTS), hydrogen peroxide (H2O2) and nitric oxide (NO) radical scavenging methods. Their anti-microbial and anti-inflammatory activities were determined by agar-well diffusion and HRBC (human red blood cell) methods, respectively.Results: All the five mango peel extracts showed good anti-oxidant activities, especially the methanolic extract of peel of Sindhura cultivar showed better IC50 values of DPPH (21.62±1.82 μg/mL), ABTS (21.33±1.94 μg/mL), H2O2 (19.87±2.61 μg/mL) and NO (57.29±2.17 μg/mL) radical scavenging activities than other extracts. It also possessed higher contents of phenolics (169.18±3.28 mg of GAE/g) and flavonoids (26.18±1.84 mg of QE/g) than the other extracts. All peel extracts of five cultivars of mango fruit revealed good anti-microbial activities against bacterial and fungal cultures and also possessed significant anti-inflammatory activity.Conclusion: The present study revealed that all the mango peel extracts have potential antioxidant activity, as well as better anti-microbial and anti-inflammatory activities.

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Antibacterial, Antifungal, and Antiviral Activities of African Medicinal Plants

Ndhlala¹,

Amoo²,

Ncube³

et al. 2013

Medicinal Plant Research in Africa

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Antimicrobial Activities of Cajanus cajan, Garcinia kola and Xylopia aethiopica on Pathogenic Microorganisms

Cited by 26 publications

References 0 publications

In Vitro Antibacterial Activity and Phytochemical Screening of Garcinia Kola Extracts Against Methicillin Resistant Staphylococcus Aureus (MRSA)

In Vitro Antibacterial Activity and Phytochemical Screening of Garcinia Kola Extracts Against Methicillin Resistant Staphylococcus Aureus (MRSA)

In vitro anti-oxidant, anti-microbial and anti-inflammatory activities of five Indian cultivars of mango (Mangifera indica L.) fruit peel extracts

Antibacterial, Antifungal, and Antiviral Activities of African Medicinal Plants

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