Antiinflammatory activity of leaf extracts ofKalanchoe crenataAndr

Abstract

The methylene chloride/methanol extract of K. crenata was ex-B.P. 812 Yaounde, Cameroon. tracted by using hexane, methylene chloride, ethyl acetate, and n-butanol. The antiin 2 Department of Animal Biology, flammatory profile of these extracts was investigated on the basis of paw edema induced Faculty of Science, University of by carrageenan. The n-butanol fraction (most potent) was further assessed through acute Dschang, BP 67 Dschang, inflammatory models induced by histamine, serotonin, and formalin. The chronic Cameroon. antiinflammatory and the ulcerogenic activities of the n-butanol fraction were 3 Department of Physiological also examined. Sciences, Faculty of Medicine Results: Results: Results: Results: Results: The oral administration of n-butanol fraction (600 mg/kg) caused a maximum and Biomedical Sciences, University of Yaounde I, inhibition of about 45% in paw edema induced by carrageenan. The n-butanol fraction Cameroon. also exhibited acute antiinflammatory activity on paw edema induced by histamine (47.51%), serotonin (54.71%), and formalin-(40.00%). In the chronic inflammation model,

Evaluation of anti-inflammatory and analgesic effects on the extracts of different parts of Excoecaria agallocha L.

“…Previous studies reported that, plants are rich in alkaloids triterpenoids, flavanoids and saponins which showed present antiinflammatory activity (Haihua Shu et al, 2006;Theophile et al, 2006;Borgi et al, 2007) Preliminary phytochemical analysis performed in this study shows the present of triterpenoids, saponins, polyphenols, steroids, tannins and flavanoids in the seed extract of E. agallocha. The anti-inflammatory activity action of triterpenoids has been reported by many researchers (Vazquez et al, 1996;Suh et al, 1998';Huss et al, 2002).…”

“…The anti-inflammatory activity action of triterpenoids has been reported by many researchers (Vazquez et al, 1996;Suh et al, 1998';Huss et al, 2002). Saponnins has also been reported to have anti-inflammatory activities by inhibition of the enzymes iNos, Cox-2 and lipoxygenase (Bermejo Benito et al, 1998;Li and Chu, 1999;Kim et al, 2002).…”

Acute and Subacute Anti-Inflammatory Activities of Dichloromethane Extract of Cassia Alata (Linn.) Leaves in Wistar Rats

“…Thirty minutes after the treatment of animals, they received subplantar injection of serotonin 1% (0.1 ml) or histamine 1% (0.1 ml). Oedema was determined 30 or 60 min after serotonin (Lanher et al, 1991;Dimo et al, 2006) or histamine injection (Dimo et al, 2006;Singh et al, 1996), respectively. Percentage of inhibition (Pi) is obtained by the previous formula.…”

In-Vitro and In-Vivo Anti-Inflammatory and Analgesic Activity of Bixa orellana Linn Leaf Extracts

“…In the present investigation, the antiinflammatory activity of different extracts of leaves of Bixa orellana were tested by (chemical) carrageenan induced rat paw edema method using Diclofenac sodium as standard [2,9,10] and in-vitro membrane stabilization of HRBCs [11,12].…”