Antifungal Flavanones and Prenylated Hydroquinones from Piper crassinervium Kunth.

Danelutte, Ana Paula; Lago, João Henrique G.; Young, Maria Cláudia Marx; Kato, Massuo Jorge

doi:10.1002/chin.200402241

Cited by 28 publications

(53 citation statements)

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“…The sub-fractions N01-N08 were screened for activity against plant pathogenic fungi by TLC bioautography (Danelutte et al, 2003;Alcerito et al, 2002;Niu et al, 2006). Fractions (50 g L −1 ) were developed on TLC plates with chloroform/ethyl acetate/formic acid 5:4:1.…”

Section: Bioautographymentioning

confidence: 99%

Phenolics and antifungal activities analysis in industrial crop Jerusalem artichoke (Helianthus tuberosus L.) leaves

Chen

Long

et al. 2013

Industrial Crops and Products

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Section: Bioautographymentioning

confidence: 99%

Phenolics and antifungal activities analysis in industrial crop Jerusalem artichoke (Helianthus tuberosus L.) leaves

Chen

Long

et al. 2013

Industrial Crops and Products

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“…1,950 species, of which the genus Piper is the largest, with more than 600 species described worldwide (Danelutte et al 2003). Besides being of high commercial and economical importance, Piper species are medicinally used in different ways, such as in the Indian Ayurvedic system of medicine and in the folklore medicine of Latin America and the West Indies (Parmar et al 1997).…”

Section: Introductionmentioning

confidence: 99%

“…Besides being of high commercial and economical importance, Piper species are medicinally used in different ways, such as in the Indian Ayurvedic system of medicine and in the folklore medicine of Latin America and the West Indies (Parmar et al 1997). Piper species produce many biologically active compounds, including amides, flavanones, alkaloids, propenylphenols, lignans, neolignans, benzoic acids and chromenes (Parmar et al 1997;Navickiene et al 2003;Silva et al 2002;Danelutte et al 2003;Martins et al 2003;Lago et al 2004).…”

Section: Introductionmentioning

confidence: 99%

In vitro morphogenesis and cell suspension culture establishment in Piper solmsianum C. DC. (Piperaceae)

et al. 2009

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RESUMO -(Morfogênese in vitro e estabelecimento de culturas de suspensão celular em Piper solmsianum C. DC. (Piperaceae)). Piper solmsianum é uma espécie herbácea do sudeste brasileiro onde vários compostos biologicamente ativos já foram identificados. O objetivo deste trabalho foi estabelecer suspensões celulares nesta espécie. Para tanto, foram utilizados explantes de pecíolos e folhas, retirados de plântulas cultivadas in vitro, os quais foram submetidos a diferentes combinações de reguladores de crescimento (AIA, ANA, 2,4-D e BAP). Foi obtida a neo-formação de raízes e brotos, estes últimos através do processo de organogênese indireta evidenciada por estudos histológicos. Para a indução e crescimento dos calos, foram avaliados, além das diferentes combinações de reguladores de crescimento, a suplementação ao meio de cultura de carvão ativado (1,5 mg.l -1 ) e o regime de luz. Culturas mantidas na luz, em meio de cultura suplementado com 0,2 mg.l -1 2,4-D e 2 mg.l -1 BAP e sem carvão ativado, resultaram em maior crescimento (massa fresca) dos calos. A partir destes calos, foram obtidas suspensões celulares, cuja dinâmica de crescimento e acúmulo de metabólitos foi estudado. Os resultados obtidos deverão ser utilizados para a caracterização de rotas biosintéticas em culturas in vitro em P. solmsianum. Palavras-chave: calogênese, morfogênese, pariparoba, reguladores de crescimento, suspensões celulares ABSTRACT -(In vitro morphogenesis and cell suspension culture establishment in Piper solmsianum C. DC. (Piperaceae)).Piper solmsianum is a shrub from Southeast Brazil in which many biologically active compounds were identified. The aim of this work was to establish a cell suspension culture system for this species. With this in mind, petiole and leaf explants obtained from in vitro plantlets were cultured in the presence of different plant growth regulator combinations (IAA, NAA, 2,4-D and BA). Root and indirect shoot adventitious formation, detected by histological analysis, was observed. Besides the different combinations of plant growth regulators, light regime and the supplement of activated charcoal (1.5 mg.l -1 ) were tested for callus induction and growth. Cultures maintained in light, on a 0.2 mg.l -1 2,4-D and 2 mg.l -1 BA supplemented medium, and in the absence of activated charcoal, showed the highest calli fresh matter increment. From a callus culture, cell suspension cultures were established and their growth and metabolite accumulation studied. The achieved results may be useful for further characterization of the activated secondary metabolites pathways in in vitro systems of P. solmsianum.

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“…Plants from the genus Piper are widely distributed throughout tropical and subtropical regions. Brazil has several species and promising studies on biological properties of plants of the Piperaceae family have been published (Navickiene et al, 2000;Danelutte et al, 2003Danelutte et al, , 2005Cysne et al, 2005;Yamaguchi et al, 2006).…”

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confidence: 99%

Molluscicidal and ovicidal activities of plant extracts of the Piperaceae on Biomphalaria glabrata (Say, 1818)

et al. 2010

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Schistosomiasis is a tropical disease caused by Schistosoma and occurs in 54 countries, mainly in South America, the Caribbean region, Africa and the eastern Mediterranean. Currently, 5 to 6 million Brazilian people are infected and 30,000 are under infection risk. Typical of poor regions, this disease is associated with the lack of basic sanitation and very frequently to the use of contaminated water in agriculture, housework and leisure. One of the most efficient methods of controlling the disease is application of molluscicides to eliminate or to reduce the population of the intermediate host snail Biomphalaria glabrata. Studies on molluscicidal activity of plant extracts have been stimulated by issues such as environmental preservation, high cost and recurrent resistance of snails to synthetic molluscicides. The aim of this study was to determine the molluscicide action of extracts from Piperaceae species on adult and embryonic stages of B. glabrata. Fifteen extracts from 13 Piperaceae species were obtained from stems, leaves and roots. Toxicity of extracts was evaluated against snails at two different concentrations (500 and 100 ppm) and those causing 100% mortality at 100 ppm concentration were selected to obtain the LC 90 (lethal concentration of 90% mortality). Piper aduncum, P. crassinervium, P. cuyabanum, P. diospyrifolium and P. hostmannianum gave 100% mortality of adult snails at concentrations ranging from 10 to 60 ppm. These extracts were also assayed on embryonic stages of B. glabrata and those from P. cuyabanum and P. hostmannianum showed 100% ovicidal action at 20 ppm.

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Antifungal Flavanones and Prenylated Hydroquinones from Piper crassinervium Kunth.

Cited by 28 publications

References 1 publication

Phenolics and antifungal activities analysis in industrial crop Jerusalem artichoke (Helianthus tuberosus L.) leaves

Phenolics and antifungal activities analysis in industrial crop Jerusalem artichoke (Helianthus tuberosus L.) leaves

In vitro morphogenesis and cell suspension culture establishment in Piper solmsianum C. DC. (Piperaceae)

Molluscicidal and ovicidal activities of plant extracts of the Piperaceae on Biomphalaria glabrata (Say, 1818)

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