Antifungal effects of the aqueous and ethanolic leaf extracts of Echinophora platyloba and Rosmarinus officinalis

Abstract

Background and Purpose :In traditional medicine, herbal products still remain the principal source of pharmaceutical agents. The present study aimed to investigate the antifungal effects of Echinophora platyloba and Rosmarinus officinalis extracts on C. albicans species.Materials and Methods :The aqueous and ethanolic leaf extracts of E. platyloba and R. officinalis, collected from the mountainous regions of Iran, were screened in terms of antimicrobial activity against C. albicans strains, using the agar well diffusion method. The minimum inhibitory concentration was determined by the microtitration technique.Results:Overall, the results showed that the leaf extracts of E. platyloba and R. officinalis had strong antimicrobial activities. Also, based on the findings, R. officinalis leaf extracts exhibited higher antimicrobial activity. The ethanolic leaf extracts of E. platyloba and R. officinalis showed good antimicrobial activity against C. albicans strains. However, the aqueous extracts did not show any major activities against the tested C. albicans strains. On the other hand, the ethanolic extracts exhibited major antimicrobial properties against C. albicans strains. The highest minimum inhibitory concentration was reported in E. platyloba leaf extracts. Conclusion:The present results indicated some advantages of E. platyloba and R. officinalis leaf extracts, which could be applied for the treatment of microbial infections.

Control of Passion Fruit Fungal Diseases Using Essential Oils Extracted from Rosemary(Rosmarinus officinalis)and Eucalyptus(Eucalyptus agglomerata)in Egerton University Main Campus Njoro, Kenya

“…The possible reason could be differences in climatic conditions. However, Sepehri et al [ 27 ] obtained results that supported the findings of this study while carrying out sensitivity test of essential oils from eucalyptus. Similarities of the test pathogens could be a contributing factor [ 28 ].…”

A review of botany and pharmacological effect and chemical composition ofEchinophoraspecies growing in Iran

“…[ 31 35 37 38 39 ] Antifungal properties of the extract on C. albicans , Aspergillus flavus , and Penicillium expansum have been proven. Moreover, antifungal properties effects of this extract at a concentration of 250 mg against dermatophytes Trichophyton verrucosum and Trichophyton schoenleinii is desirable and Trichophyton mentagrophytes , Microsporum canis , and Epidermophyton floccosum depending on the circumstances and how serious the infection is are usable,[ 40 41 42 43 44 45 46 47 48 ] and antifungal effects essence of the extract of this species on the fungus Candida tropicalis , Robrardoterolla , Rhodotorula mucilaginosa , C. albicans , Fusarium graminearum ,[ 49 50 ] and anticancer, antimutation, and apoptosis related to the extract on cancer cells of blood, lung, and prostate have been reported. [ 51 52 53 ] The effects of the extract on premenstrual syndrome (dysmenorrhea),[ 54 55 56 57 58 59 ] effects of the extract on reducing blood fat, liver, kidney protection, increasing the secretion of testosterone, and strengthening sexual activity, effective on pituitary-thyroid axis hormones,[ 60 61 62 ] central and peripheral analgesic effect of the extract,[ 63 ] healer's effect on wound healing,[ 64 ] and insecticidal properties of essential oil on Tribolium castaneum ( Herbst ), Callosobruchus maculatus , and Rhyzopertha dominica [ 65 ] have been established.…”

“…This can result in somehow moderate disorders and consequently loss of hormones in the menstrual, such as premenstrual syndrome and dysmenorrhea. [ 47 54 87 ] Since the muscles in the human uterus are smooth muscles, the extract of this plant can probably apply its antispasmodic effect on it, resulting in the pain reduction during menstruation. [ 57 ] Compounds such as saponins, alkaloids, flavonoids, and terpenes in this plant can reduce body weight and blood fat and protect liver and kidney.…”

The antibacterial and antibiofilm activity of sea anemone (Stichodactyla haddoni) against antibiotic-resistant bacteria and characterization of bioactive metabolites

“…Sea anemones, like other coelenterates, produce many biologically active polypeptides and proteins, including neurotoxins, pore-forming toxins (or cytolysins), phospholipases and proteinase inhibitors (Thangaraj and Bragadeeswaran 2012;Sepehri et al 2016). Therefore, they have evolved the ability to synthesize toxic compounds obtained from marine microorganisms.…”