Antifreeze Proteins:  Structures and Mechanisms of Function

Yeh, Yung‐Hsin; Feeney, Robert E.

doi:10.1021/cr950260c

Cited by 512 publications

(487 citation statements)

References 103 publications

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“…Also, dendrites have been observed during the formation of cubically ordered silica micelle structures [9] and during the growth of bacterial colonies [10]. Finally, an understanding of dendrite growth may play a key role in elucidating the mechanisms of biological ''anti-freeze'' proteins [11].…”

Section: Introductionmentioning

confidence: 99%

Atomistic and continuum modeling of dendritic solidification

Hoyt

2003

Materials Science and Engineering: R: Reports

397

220

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Section: Introductionmentioning

confidence: 99%

Atomistic and continuum modeling of dendritic solidification

Hoyt

2003

Materials Science and Engineering: R: Reports

397

220

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“…Thus, an understanding of properties of these proteins that lead to stabilization of biomaterials is of immediate interest. The best available evidence suggests that the proteins interact at or in the ice-water interface during freezing (Hew & Yang, 1992;Yeh & Feeney, 1996) or with the phospholipid bilayers that comprise biological membranes during cooling (Hays et al, 1996;Tablin et al, 1996). These interactions must depend on the availability of appropriate peptide functional groups for binding to the ice-water interface or membranes, and therefore, the mechanism must take into account the conformational properties of the peptide.…”

mentioning

confidence: 99%

“…1984), unlike in other antifreeze proteins (Davies & Sykes, 1997). However, there are several alternative models for the preferred conformations of these peptides (Bush et al, 1984;Bush & Feeney, 1986;Rao & Bush, 1987;Dill et ai., 1992;Drewes & Rowen, 1993;Yeh & Feeney, 1996), so that models of the ice-peptide interactions are highly ambiguous. In this article, we report an NMR examination of the conformational and dynamical properties of AFGP-8.…”

mentioning

confidence: 99%

Conformational and dynamic properties of a 14 residue antifreeze glycopeptide from antarctic cod

Lane¹,

Hays

Feeney

et al. 1998

Protein Science

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The 'H and I3C NMR spectra of a 14-residue antifreeze glycopeptide from Antarctic cod (Tetramatornus horchgrevinki) containing two proline residues have been assigned. I3C NMR relaxation experiments indicate motional anisotropy of the peptide, with a tumbling time in water at 5°C of 3-4 ns. The relaxation data and lack of long-range NOEs are consistent with a linear peptide undergoing significant segmental motion. However, extreme values of some coupling constants and strong sequential NOEs indicate regions of local order, which are most evident at the two ATPA subsequences. Similar spectroscopic properties were observed in the 16-residue analogue containing an Arg-Ala dipeptide added to the C-terminus. Molecular modeling also showed no evidence of long-range order, but the two ATPA subsequences were relatively well determined by the experimental data. These motifs were quite distinct from helical structures or p turns commonly found in proteins, but rather resemble sections of an extended polyproline helix. Thus, the NMR data provide a description of the local order, which is of relevance to the mechanism of action of the antifreeze activity of the antifreeze glycopeptides as well as their ability to protect cells during hypothermic storage.

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“…148 Synthesis of these proteins has been successful and their ability of hydrate inhibition is as good as expected. 138 Kuznetsova et al 150 used up to a PVP octamer in their simulations with methane and water.…”

Section: Hydrate Inhibitionmentioning

confidence: 89%

Problems Associated with Sour Gas in the Oilfield Industry and Their Solutions

2015

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. (2015) 'The problems associated with sour gas in the oil eld industry and their solutions.', Energy fuels., 29 (8). pp. 4667-4682. Further information on publisher's website:http://dx.doi.org/10.1021/acs.energyfuels.5b00952Publisher's copyright statement:This document is the Accepted Manuscript version of a Published Work that appeared in nal form in Energy Fuels, copyright c 2015 American Chemical Society after peer review and technical editing by the publisher. To access the nal edited and published work see http://dx.doi.org/10.1021/acs.energyfuels.5b00952.Additional information:Use policyThe full-text may be used and/or reproduced, and given to third parties in any format or medium, without prior permission or charge, for personal research or study, educational, or not-for-pro t purposes provided that:• a full bibliographic reference is made to the original source • a link is made to the metadata record in DRO • the full-text is not changed in any way The full-text must not be sold in any format or medium without the formal permission of the copyright holders.Please consult the full DRO policy for further details. AbstractFossil fuels are still a necessary and important part of modern living, keeping cars running and houses heated for example. As demands have risen and reservoirs of oil and natural gas have depleted, it has become increasingly more important to tap in to fields that were once classified as undesirable. Sour fields, fields high in acidic gases such as hydrogen sulfide and carbon dioxide, are one such option. There are many difficulties and dangers associated with working sour fields, such as toxicity of the sour gases, hydrate formation and corrosion of equipment that have prevented these resources being used in the past. Many varied methods of overcoming these problems have been developed, from removing the sour components to inhibiting their effects. This review highlights the major issues raised by sour fields as well as a wide range of solutions in use today.

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Antifreeze Proteins: Structures and Mechanisms of Function

Cited by 512 publications

References 103 publications

Atomistic and continuum modeling of dendritic solidification

Atomistic and continuum modeling of dendritic solidification

Conformational and dynamic properties of a 14 residue antifreeze glycopeptide from antarctic cod

Problems Associated with Sour Gas in the Oilfield Industry and Their Solutions

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