Anticoagulant treatment for subsegmental pulmonary embolism

Yoo, Hugo HB; Nunes-Nogueira, Vania Santos; Bôas, Paulo José Fortes Villas

doi:10.1002/14651858.cd010222.pub4

Cited by 15 publications

(18 citation statements)

References 61 publications

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“…Modern computed tomography scanning techniques can now detect small PE in subsegmental pulmonary arteries that are of uncertain clinical significance. No randomized controlled trials to date have adequately explored the question of whether anticoagulant treatment of isolated subsegmental PE confers clinical benefit [38]. Ongoing trials will explore whether anticoagulation treatments for isolated subsegmental pulmonary emboli meaningfully impact patient-centered outcomes [39].…”

Section: Venous Thromboembolism Exists In a Hierarchy Of Clinical Impmentioning

confidence: 99%

Prevention of Venous Thromboembolism in 2020 and Beyond

Nicholson

Chan

Bhagirath

et al. 2020

JCM

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Venous thromboembolism (VTE) is the third most common cause of vascular mortality worldwide and comprises deep-vein thrombosis (DVT) and pulmonary embolism (PE). In this review, we discuss how an understanding of VTE epidemiology and the results of thromboprophylaxis trials have shaped the current approach to VTE prevention. We will discuss modern thromboprophylaxis as it pertains to genetic risk factors, exogenous hormonal therapies, pregnancy, surgery, medical hospitalization, cancer, and what is known thus far about VTE in COVID-19 infection.

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Section: Venous Thromboembolism Exists In a Hierarchy Of Clinical Impmentioning

confidence: 99%

Prevention of Venous Thromboembolism in 2020 and Beyond

Nicholson

Chan

Bhagirath

et al. 2020

JCM

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“…However, asymptomatic PE may have been overlooked, and it was reported that peripheral PE was usually found in patients with few or no symptoms. 38 Prasad and colleagues suggested that anticoagulant therapy had little benefit for peripheral PE and increased the incidence of adverse events. 39 In the present study, we found that the rate of disappearance of unilateral distal DVT was higher than that of bilateral distal DVT on the 30th day of anticoagulant therapy (92.5% vs 79.2%), while the two DVT locations had similar rates of disappearance on the 90th day of anticoagulant therapy (95.0% vs 95.8%).…”

Section: Discussionmentioning

confidence: 99%

Construction and Validation of a Nomogram for Predicting the Risk of Deep Vein Thrombosis in Hepatocellular Carcinoma Patients After Laparoscopic Hepatectomy: A Retrospective Study

Yao

Zhao

Zhang

et al. 2021

JHC

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Background:The incidence of deep vein thrombosis (DVT) in hepatocellular carcinoma (HCC) patients after laparoscopic hepatectomy (LH) is unclear, and there is no effective method for DVT risk assessment in these patients. Methods: The data from the total of 355 consecutive HCC patients who underwent LH were included. A DVT risk algorithm was developed using a training set (TS) of 243 patients, and its predictive performance was evaluated in both the TS and a validation set (VS) of 112 patients. The model was then used to develop a DVT risk nomogram (TRN). Results: The incidence of DVT in the present study was 18.6%. Age, sex, body mass index (BMI), comorbidities and operative position were independent risk factors for DVT in the TS. The model based on these factors had a good predictive ability. In the TS, it had an area under the receiver operating characteristic (AUC) curve of 0.861, Hosmer-Lemeshow (H-L) goodness of fit p value of 0.626, sensitivity of 44.4%, specificity of 96.5%, positive predictive value (PPV) of 74.1%, negative predictive value (NPV) of 88.4%, and accuracy of 86.8%. In the VS, it had an AUC of 0.818, H-L p value of 0.259, sensitivity of 38.1%, specificity of 98.9%, PPV of 88.9%, NPV of 87.4%, and accuracy of 87.5%. The TRN performed well in both the internal and the external validation, indicating a good clinical application value. The TRN had a better predictive value of DVT than the Caprini score (p < 0.001). Conclusion:The incidence of DVT after LH was high, and should not be neglected in HCC patients. The TRN provides an efficacious method for DVT risk evaluation and individualized pharmacological thromboprophylaxis.

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“…Hemagglutination is a physicochemical phenomenon that involves separation of blood particles from the fluid medium. This is highly important in blood transfusion, blood typing and blood thinning drug (anticoagulant) development [46–48]

true Z = f ([] σ, \frac{1}{D}, \frac{1}{\sqrt{D μ}})

…”

Section: Importance and Application Of Zeta Potentialmentioning

confidence: 99%

Revisiting Zeta Potential, the Key Feature of Interfacial Phenomena, with Applications and Recent Advancements

et al. 2022

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Surface of a particle is inevitably charged. When the particle is surrounded by a fluid a potential difference arises between the surface and bulk, called zeta potential (ζ) which controls many interfacial properties of the particle involving in suspension, emulsion, colloid etc. Many phenomena happening around us have at least one step that passes through an interface. Thus, the application of ζ is practically uncountable. Discovered in late 19th century, almost past 120 years, the application of ζ has emerged in many areas to meet the fruitful need of mankind. However, to the best of our knowledge, there is no report disclosed citing the applications at one place as a ready tool for the readers. The present review accumulates extensive survey of literature, bringing out various aspects of ζ in chemistry, engineering, biology, material, and environmental sciences. A brief theoretical background mentioning the principle and practical applications were focused.

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Anticoagulant treatment for subsegmental pulmonary embolism

Abstract: Editorial group: Cochrane Vascular Group. Publication status and date: New search for studies and content updated (no change to conclusions), published in Issue 2, 2020.

Cited by 15 publications

References 61 publications

Prevention of Venous Thromboembolism in 2020 and Beyond

Prevention of Venous Thromboembolism in 2020 and Beyond

Construction and Validation of a Nomogram for Predicting the Risk of Deep Vein Thrombosis in Hepatocellular Carcinoma Patients After Laparoscopic Hepatectomy: A Retrospective Study

Revisiting Zeta Potential, the Key Feature of Interfacial Phenomena, with Applications and Recent Advancements

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