Antibody Responses of Young Carp, Cyprinus Carpio, and Grey Mullet, Chelon Labrosus, Immunized With Soluble Antigen by Various Routes

Humoral immune responses of channel catfish (Ictalurus punctatus) fry and fingerlings exposed toEdwardsiella ictaluri

“…The earliest age at which di#erent species of fish can produce antibodies varies greatly and is dependent on water temperature, antigen used and route of administration, but no oviparous teleosts have demonstrated the ability to produce an acquired immune response within 1 week post-hatch. Rainbow trout demonstrate antibody production against Aeromonas hydrophila when exposed at 3 weeks post-hatch (Secombes, 1981) and to dinitrophenol-keyhole limpet haemocyanin when exposed at 1 month post-hatch (Mughal & Manning, 1985), but not before these ages. In the present study, the decrease in specific antibody titre after primary bacterial exposure observed in fish aged 1 and 3 weeks post-hatch was probably due to agglutination by nonspecific pre-existing antibodies that may have been of maternal origin.…”

The ontogeny of mucosal immune cells in common carp (Cyprinus carpio L.)

“…The 'lag' period between appearance of B cells in head kidney and spleen compared to mucosal organs corresponds with data obtained for sea bass (Dicentrarchus labrax; Picchietti et al 1997) and spotted wolffish (Anarhichas minor; Grontvedt and Espelid 2003). The appearance of 'mature' B cells in peripheral organs (intestine and gills) at 5-6 wpf corresponds to the appearance of plasma cells (KoumansVan Diepen et al 1994), and the mounting of antibody responses against Aeromonas salmonicida (Mughal and Manning 1985). B cells appeared in the skin considerably later than in intestine, which is consistent with data in spotted wolffish (Grontvedt and Espelid 2003).…”

“…Cells (Romano et al 1998) and humoral factors (Huttenhuis et al 2005a) of the innate immune system are already present at 2 dpf, while the thymus (the first organ of the adaptive immune system) starts developing from 3 to 4 dpf (Romano et al 1999;Huttenhuis et al 2005). Systemic antibody responses appear considerably later at 1-2 months, while juvenile tolerance is evoked before this age (Mughal and Manning 1985;Van Muiswinkel et al 1985;Mughal et al 1986). Knowledge on the ontogeny of the mucosal immune system in carp however is limited.…”

Reponse immunitaire humorale induite par le virus de la necrose pancreatique infectieuse (VNPI) chez la truite mouchetee (Salvelinus fontinalis L ) et caracterisation de l immunoglobuline produite

“…La température est un facteur de modulation très significatif de la réponse immunitaire (DeKinkelin, 1985). On constate que la cinétique de l'immunité à médiation humorale et cellulaire est lente à basse température, alors qu'une réponse plus forte est obtenue à la température physiologique optimale pour une espèce donnée (Mughal et Manning, 1985). (Mughal et Manning, 1985).…”

“…On constate que la cinétique de l'immunité à médiation humorale et cellulaire est lente à basse température, alors qu'une réponse plus forte est obtenue à la température physiologique optimale pour une espèce donnée (Mughal et Manning, 1985). (Mughal et Manning, 1985). On croit que la phase subséquente de multiplication et de différenciation des lymphocytes B est indépendante de la température (Ellis, 1982).…”