Antibiotic Resistance Pattern of Bacterial Pathogens in Elderly Patients Admitted in the Intensive Care Unit

Abstract

To identify and to determine the resistance pattern of bacterial pathogens involved in infections of the elderly patients (� 65 years) admitted in the intensive care unit (ICU) at County Emergency Clinical Hospital Craiova, Romania. A retrospective study of bacterial pathogens was carried out on 463 elderly patients (� 65 years) admitted to the ICU, from January to December 2017. The analysis of the resistance patterns for the action of the appropriate antibiotics was performed using Vitek 2 Compact system and diffusion method. In this study there were analyzed 617 samples from 463 elderly patients (� 65 years). A total of 776 bacterial isolates were obtained, of which 175 strains of Klebsiella spp. (22.55%), followed by MRSA - Methicillin-Resistant Staphylococcus Aureus (108 -13.91%) and Escherichia coli (99 -12.75%). The most common isolates were from respiratory tract (572 isolates -73.71%). High rates of MDR were found for Pseudomonas (73.07%), MRSA (62.03%) and Klebsiella (44.57%). The study revealed an alarming pattern of antibiotic resistance in the majority of ICU isolates from elderly patients (�65 years), which draws attention to the need for judicious use of antibiotics and for careful monitoring of the drug resistance of patients.

The Characterization of Antibiotic Resistance of Bacterial Isolates from Intensive Care Unit Patient Samples in a University Affiliated Hospital in Romania

“…The first two germs were also identified in the samples collected from elderly patients hospitalized in the same period in ICU. [18] Klebsiella ranks first among isolated germs in other researchers' studies [19], while a similar percentage was also highlighted for this pathogen [20,21], but occupying the second, third or fourth place in the hierarchy of the most frequent pathogens involved in infections of patients hospitalized in ICU, after Acinetobacter spp. [20,22], Pseudomonas [21] or E. coli [23].…”

Bacterial Isolates from Endotracheal Aspirates and their Antimicrobial Resistance Pattern in Patients from Intensive Care Unit

“…A worrying phenomenon in Romania is also the existence of the MDR-TB and XDR-TB cases in socioeconomic conditions (malnutrition, agglomeration, stress), with the doubling of number of cases of XDR-TB in the last years, including the cases of extrapulmonary tuberculosis which originates from the hematogenous metastatic affects developed during the prime TB infection period [28][29][30] All these observations are in line with the results of other studies we have conducted to identify germs involved in the production of infections in patients hospitalized in ICU. [31,32].…”

Lung Body Plethysmography: From Functional to Clinical Aspects for Prediction of Quality of Life in Patients with Chronic Pulmonary Obstruction

“…The same high displacement of VRP% by PA was also obtained for patients who were smokers at the time of the determinations ( Figure 5). The additional exposure to industrial chemicals, dust, gases or presence of comorbidities such as diabetes mellitus, hypertension, tuberculosis, pulmonary neoplasm, other neoplasms and infections may be risk factors correlated with the severity of hyperinflation [12][13][14][15][16][17].…”