Antibiotic resistance in the cultivable plaque microbiota of children from different ethnic groups

Ready, Derren; Lancaster, Holli; Mullany, Peter; Bedi, Raman; Wilson, Michael

doi:10.1016/j.ijantimicag.2006.02.008

Cited by 5 publications

(5 citation statements)

References 32 publications

(29 reference statements)

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“…Species identification was carried out using the api strip system (API20, API20NE, Biomerieux, UK). Isolates that could not be identified using these methods were characterized by partial sequencing of the 16S rRNA gene, as described previously (Ready et al 2006).…”

Section: Methodsmentioning

confidence: 99%

Randomized controlled trial of toothbrushing to reduce ventilator-associated pneumonia pathogens and dental plaque in a critical care unit

Needleman

Hirsch

Leemans

et al. 2011

Journal of Clinical Periodontology

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Section: Methodsmentioning

confidence: 99%

Randomized controlled trial of toothbrushing to reduce ventilator-associated pneumonia pathogens and dental plaque in a critical care unit

Needleman

Hirsch

Leemans

et al. 2011

Journal of Clinical Periodontology

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“…Most tet genes originated from periodontal pathogens such as P. gingivalis and F. nucleatum [23]. The percentage of tetracycline-resistant isolates in dental plaque-associated bacteria is high in children from South Asia and Japan [24]. Isolates of T. denticola that are resistant to tetracycline have also been reported [25].…”

Section: Antibiotic Therapy and Drug Resistance In Periodontal Bacteriamentioning

confidence: 99%

Advances in novel therapeutic approaches for periodontal diseases

et al. 2022

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Periodontal diseases are pathological processes resulting from infections and inflammation affecting the periodontium or the tissue surrounding and supporting the teeth. Pathogenic bacteria living in complex biofilms initiate and perpetuate this disease in susceptible hosts. In some cases, broad-spectrum antibiotic therapy has been a treatment of choice to control bacterial infection. However, increasing antibiotic resistance among periodontal pathogens has become a significant challenge when treating periodontal diseases. Thanks to the improved understanding of the pathogenesis of periodontal disease, which involves the host immune response, and the importance of the human microbiome, the primary goal of periodontal therapy has shifted, in recent years, to the restoration of homeostasis in oral microbiota and its harmonious balance with the host periodontal tissues. This shift in therapeutic goals and the drug resistance challenge call for alternative approaches to antibiotic therapy that indiscriminately eliminate harmful or beneficial bacteria. In this review, we summarize the recent advancement of alternative methods and new compounds that offer promising potential for the treatment and prevention of periodontal disease. Agents that target biofilm formation, bacterial quorum-sensing systems and other virulence factors have been reviewed. New and exciting microbiome approaches, such as oral microbiota replacement therapy and probiotic therapy for periodontal disease, are also discussed.

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“…Notably, it was recently suggested that oral streptococci are a natural source of antibiotic resistance gene transfers in active dental infections; Streptococcus mutans , gordonii , oralis , sanguinis , and salivarius were the main streptococci involved . Therefore, antibiotic‐resistant oral bacteria have the opportunity for rapid dissemination and the ability to transfer their resistance genes to other bacterial species …”

Section: Oral Microbiota and Antibiotic Resistancementioning

confidence: 99%

“…10,35 Therefore, antibiotic-resistant oral bacteria have the opportunity for rapid dissemination and the ability to transfer their resistance genes to other bacterial species. 36 T A B L E 1 Bacterial resistance and breakpoints of antibiotics used in antibiotic prophylaxis for IE…”

Section: Oral Microbiota and Antibiotic Resistancementioning

confidence: 99%

Prevention of infective endocarditis and bacterial resistance to antibiotics: A brief review

Loyola-Rodríguez

Miranda

Loyola-Leyva

et al. 2019

Special Care in Dentistry

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The purpose of this statement is to debate the recommendations of the American Heart Association (AHA) for the prevention of infective endocarditis through an antibiotic prophylaxis protocol and its relation with bacterial resistance to antibiotics. Since dental infections involve biofilms that include several bacterial species (Gram‐negative and Gram‐positive), it is essential, from the dental point of view, to consider the frequency, magnitude, and duration of bacteremia associated with active dental infections before applying antibiotic prophylaxis. The actual guidelines for antibiotic prophylaxis should be revised according to recent evidence of bacterial resistance. Amoxicillin/clavulanic acid and moxifloxacin should be considered due to their effectiveness against bacteria associated with oral, GU, and GI infections and the low rates of antibiotic resistance associated with these antibiotics, instead of the actual protocol, which includes amoxicillin (2 g) or clindamycin (600 mg) administered an hour before the dental procedures. The breaking point to test the antibiotic bacterial resistance (ABR) had a wide range in the different studies that were analyzed, which could explain the widely varied ABR percentages reported for the various antibiotics used for antibiotic prophylaxis.

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Antibiotic resistance in the cultivable plaque microbiota of children from different ethnic groups

Cited by 5 publications

References 32 publications

Randomized controlled trial of toothbrushing to reduce ventilator-associated pneumonia pathogens and dental plaque in a critical care unit

Randomized controlled trial of toothbrushing to reduce ventilator-associated pneumonia pathogens and dental plaque in a critical care unit

Advances in novel therapeutic approaches for periodontal diseases

Prevention of infective endocarditis and bacterial resistance to antibiotics: A brief review

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