This study suggests that PBDNA could have a role on the RA aetiology. The possible pathway of transport of PBDNA from mouth to joints could be via the free form of DNA.
Some genotypes and haplotypes are associated with the diseases. But it seems that the genetic background of the association between RA and PE needs to be explored deeper.
Objective Determining dental caries' experience, prevalence and severity in students applying for degree courses at San Luis Potosi University (UASLP). Material and Methods A cross-sectional study was carried out involving adolescents and young adults (16 to 25 years old) applying for undergraduate courses at UASLP (~10 %, n=1 027). Two standardized examiners undertook dental examinations; DMFT index, prevalence (DMFT>0), severity (DMFT>3 and DMFT>6) and significant caries index (SiC) were calculated. STATA 9.0 non-parametric tests were used for statistical analysis. Results Mean age was 18.20±1.65; 48.0% were female. The DMFT index was 4.04±3.90 and caries prevalence was 74.4%. Regarding caries' severity, 48.8% had MDFT>3 and 24% DMFT>6. The SiC index was 8.64. Females had higher caries experience than males (4.32±4.01 cf 3.78±3.78; p<0.05), but similar prevalence and severity (p>0.05). Age was associated with both experience (p<0.001) and prevalence (p<0.01) and to differing degrees of caries' severity (p<0,001). The «filled teeth» component had the highest DMFT index percentage (63.6%) and «missing teeth» the lowest (11.4%). Conclusions High dental caries' experience, prevalence and severity were observed in this sample of adolescents and young adults. Restorative experience was high (59.5%) compared to studies carried out in other parts of Mexico and Latin-America.
Aim: To determine the association among dental caries, obesity and insulin resistance in Mexican adolescents.Methods: Body Mass Index, obesity (OB) blood pressure, insulin level, insulin resistance (IR), triglycerides level, serum HDL-cholesterol (cHDL), DMFT index and salivary flow were measured. Results:Anthropometric measures showed a significant statistical difference (p < 0.05). Insulin level was 8.98 for healthy subjects, whereas for OB-IR group was 25.35, there was a statistical significant difference (p <0.05). Triglycerides level was 88.50 for healthy subjects and 169.40 mg/dL for OB-IR; cHDL was 52.88 for healthy and 41.82 mg/dL for OB-IR group, both showed a statistically significant difference (p < 0.05). Salivary flow was 4.30 for healthy and for OB-IR group was 5.48 ml/min showed a significant statistical difference(p < 0.05). DMFT index was 3.02 for healthy and for OB-IR adolescents was 4.78, showed a significant statistical difference (p < 0.05). The caries component of DMFT index was 1.84 for healthy and was 3.52 for OB-IR adolescents, showed a significant statistical difference (p < 0.05). According to the multivariate analysis, DMFT (OR=3.10; IC95%=0.20-1.02, p=0.042) and decay (OR=3.30; IC95%=0.19-1.0,p=0.011) were associated with subjects with OB-IR. Conlusion: OB-IR Mexican adolescents showed a positive association with DMFT.
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