Antibiotic Resistance among Commensal Escherichia coli Isolated from Faeces of Cattle in Ado-Ekiti, Nigeria

Ajayi, Abraham; Oluyege, A. O.; Olowe, Olugbenga Adekunle; Famurewa, O.

doi:10.3923/javaa.2011.174.179

Cited by 18 publications

(36 citation statements)

References 7 publications

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“…In contrast with other Nigerian reports [6,19,20], bovine E. coli isolates did not show considerable resistance, which may be attributed to less bovine antibiotic dosing in this geographic location. The predominant resistance rate was seen for tetracycline (44%), followed by trimethoprim (25%).…”

Section: Discussioncontrasting

confidence: 99%

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Occurrence of extended-spectrum beta-lactamases in human and bovine isolates of Escherichia coli from Oyo state, Nigeria

Inwezerua

Mendonça

Calhau

et al. 2014

J Infect Dev Ctries

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Introduction: The main objective of the study was the molecular characterization of extended spectrum β-lactamases (ESBL) in Escherichia coli isolates collected from human and bovine samples in Oyo state, Nigeria. Methodology: Between August 2010-2011, 114 E. coli isolates were collected from hospitals (n = 57) and bovine (n = 57). PCR and sequencing were used for identification of ESBLs, upstream sequences, plasmid-mediated quinolone resistance (PMQR) genes and class 1 integrons. Plasmid incompatibility groups were identified among ESBL-positive isolates by PCR. Genetic relatdness was assessed by rep-PCR and MLST. Transfer of ESBL determinants to the recipient strain E. coli J53 was performed by broth mating assays. Results: CTX-M15 was the unique ESBL found in eight human isolates. Six CTX-M-15 producers also carry the aac(6')-lb-cr gene and/or qnrB gene, and class 1 integrons. FIA, FIB, H11, H12, F, Y and K were the plasmid replicon types found. CTX-M-15 and PMQR determinants were transferred by conjugation in two E. coli assigned by MLST to ST131 and ST2695, a new allele. Conclusions: The study highlights the dissemination hability of CTX-M-15 associated with PMQR, and the presence of class 1 integrons, able to capture additional genes, justifying the urgent need of antimicrobial resistance surveillance in Nigeria.

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Section: Discussioncontrasting

confidence: 99%

“…The predominant resistance rate was seen for tetracycline (44%), followed by trimethoprim (25%). Resistance to amoxicillin was detected in 23% of the strains, correlating with data obtained from reports on bacteria isolated from meat tables in the geographical location where the study was conducted [20].…”

Section: Discussionsupporting

confidence: 82%

Occurrence of extended-spectrum beta-lactamases in human and bovine isolates of Escherichia coli from Oyo state, Nigeria

Inwezerua

Mendonça

Calhau

et al. 2014

J Infect Dev Ctries

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“…11,13 Although there are a number of studies on antimicrobial resistance in E. coli from food animals in the western world, there is a paucity of data on prevalence of multi-drug resistant (MDR; resistance to ‡ 2 antimicrobials) E. coli from food animals in developing countries such as Nigeria. 4,6,21,24 This information is useful to compare trends in resistance in countries where antimicrobial use in both humans and animals is poorly regulated. In Nigeria, the major sources of meat consumed are beef and poultry and food-producing animals serve as major sources of meat to the population of Lagos State, Nigeria, which currently comprises more than 21 million people (www.lagosstate.nig).…”

Section: Introductionmentioning

confidence: 99%

“…11 Furthermore, MDR E. coli from food animals are prevalent in Nigeria as reported in one study where 71 different MDR types were identified in E. coli from cattle. 4 Although prevalence of commensal E. coli and their antimicrobial resistance patterns were determined in previous studies, 4,6,21,24 few of those studies included E. coli from all major meat animals consumed in Nigeria and none tested the isolates against a wide range of antimicrobials primarily used for treating human infections. The purpose of this study was to determine prevalence and antimicrobial resistance of E. coli isolated from chicken, cattle, and swine in Lagos, Nigeria.…”

Section: Introductionmentioning

confidence: 99%

“…Previous studies on prevalence and antimicrobial resistance of commensal E. coli from food animals from different parts of Nigeria have reported high levels of resistance. 4,6,21,24 Of particular concern is resistance to antimicrobials such as aminoglycosides, cephalosporins, fluoroquinolones, and sulfonamides that are commonly used to treat human infections caused by Gram-negative bacteria. 11 Furthermore, MDR E. coli from food animals are prevalent in Nigeria as reported in one study where 71 different MDR types were identified in E. coli from cattle.…”

Section: Introductionmentioning

confidence: 99%

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Prevalence and Antimicrobial Resistance inEscherichia colifrom Food Animals in Lagos, Nigeria

Adenipekun

Jackson

Oluwadun

et al. 2015

Microbial Drug Resistance

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Foodborne bacteria are often associated with human infections; these infections can become more complicated to treat if the bacteria are also resistant to antimicrobials. In this study, prevalence, antimicrobial resistance, and genetic relatedness of Escherichia coli among food producing animals from Lagos, Nigeria, was investigated. From December 2012 to June 2013, E. coli were isolated from fecal samples of healthy cattle, chicken, and swine. Antimicrobial susceptibility testing against 22 antimicrobials was performed using broth microdilution with the Sensititre™ system. Clonal types were determined by pulsed-field gel electrophoresis (PFGE). From the analysis, 211/238 (88.7%), 170/210 (81%), and 136/152 (89.5%) samples from cattle, chicken, and swine, respectively, were positive for E. coli. A subset of those isolates (n=211) selected based on β-lactamase production was chosen for further study. Overall, E. coli exhibited the highest resistance to tetracycline (124/211; 58.8%), trimethoprim/sulfamethoxazole (84/211; 39.8%), and ampicillin (72/211; 34.1%). Approximately 40% of the isolates were pan-susceptible, and none of the isolates were resistant to amikacin, cefepime, ceftazidime, ertapenem, meropenem, or tigecycline. Among the resistant isolates, 28 different resistance patterns were observed; 26 of those were characterized as multi-drug resistant (MDR; resistance to ≥2 antimicrobials). One isolate was resistant to 13 different antimicrobials representing five different antimicrobial classes. Using PFGE, MDR E. coli were genetically diverse and overall did not group based on source; identical PFGE patterns were detected among isolates from different sources. These results suggest that isolates cannot be attributed to specific sources, and some may be present across all of the sources. Results from this study indicate that food-producing animals in Nigeria are a reservoir of MDR E. coli that may be transferred to humans via the food chain.

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Prevalence, characterization and antibiotic resistance of Shiga toxigenic Escherichia coli serogroups isolated from fresh beef and locally processed ready-to-eat meat products in Lagos, Nigeria

Fayemi

Akanni

Elegbeleye

et al. 2021

International Journal of Food Microbiology

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Antibiotic Resistance among Commensal Escherichia coli Isolated from Faeces of Cattle in Ado-Ekiti, Nigeria

Cited by 18 publications

References 7 publications

Occurrence of extended-spectrum beta-lactamases in human and bovine isolates of Escherichia coli from Oyo state, Nigeria

Occurrence of extended-spectrum beta-lactamases in human and bovine isolates of Escherichia coli from Oyo state, Nigeria

Prevalence and Antimicrobial Resistance inEscherichia colifrom Food Animals in Lagos, Nigeria

Prevalence, characterization and antibiotic resistance of Shiga toxigenic Escherichia coli serogroups isolated from fresh beef and locally processed ready-to-eat meat products in Lagos, Nigeria

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