Antibiotic-Producing Bacteria of the Ocular Flora*

Halbert, Seymour P.; Swick, Lois

doi:10.1016/0002-9394(52)90259-6

Cited by 21 publications

(6 citation statements)

References 13 publications

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“…The density of the indicator lawn is an important determinant of the sensitivity of the method (172). The lawn is generally seeded before inoculation of the test strains (277) but, alternatively, may be sprayed onto the surface subsequent to inoculating the potential antagonists (99,100,129,150,153,222). Variations of this procedure include the use of overlapping drops (12,239) and also of wells cut into freshly seeded pour plate cultures and filled with agar containing the test organism (242).…”

Section: Methods Of Demonstrating Antagonismmentioning

confidence: 99%

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Bacteriocins of gram-positive bacteria.

Tagg¹,

Dajani²,

Wannamaker³

1976

Bacteriological Reviews

961

538

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Producer organism No. tested Bacillus cereus 24 B. megaterium 200 B. megaterium 100 B. stearothermophilus 22 B. thuringiensis 24 B. thuringiensis 17 Clostridium botulinum 12 C. perfringens 35 C.perfringens 237 C.perfringens 33 C. sporogenes Clostridium spp. 106 Corynebacterium diphtheriae 441 C. diphtheriae 108 C. fermentans 29 C. pseudodiphtheriae 134 Corynebacterium spp. 308 Corynebacterium spp. 383 Lactobacillus fermenti 121 Lactobacillus spp. 199 Lactobacillus spp. 100 Listeria monocytogenes 8 L. monocytogenes 51 Mycobacterium spp.

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Section: Methods Of Demonstrating Antagonismmentioning

confidence: 99%

“…Some bacteriocins require solid medium for production. Their recovery in solution is generally effected by freeze-thaw elution from the agar (99,100,173,277).…”

Section: Bacteriol Revmentioning

confidence: 99%

Bacteriocins of gram-positive bacteria.

Tagg¹,

Dajani²,

Wannamaker³

1976

Bacteriological Reviews

961

538

View full text Add to dashboard Cite

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“…So sind z. B. manche koagulasenegative Staphylokokken in der Lage, antibiotikaähnliche Suhstanzen zu produzieren, die gegenuber grampositiven Keimen inhibitorische Eigenschaften aufweisen (22) und deren biologische Wirksamkeit tierexperimentell nachweisbar ist (13,14,15,16,17,18,19). Es ist denkbar, daB auth andere Spezies auf Keime der Umgebung hemmende Eigenschaften entwickeln.…”

Section: Diskussionunclassified

Über die Standortflora der menschlichen Bindehaut: Untersuchungen von 135 Personen unterschiedlichen Alters

Thiel

Schumacher²

1994

Klin Monatsbl Augenheilkd

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With increasing age aerobic cocci are found less frequently in favor of the Corynebacteria. The proportion of anaerobic cocci increases among the anaerobes, while Propionibacteria are demonstrated less frequently. The significance of the organisms found in conjunctiva by this study for the first time is still unclear. No qualitative or quantitative sex-specific influence on the development of conjunctival flora was found.

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“…In addition, this information may assist in determining how the precorneal defense mechanisms against these microorganisms are impaired by the presence of a contact lens. The effect of contact lens wear on normal ocular bacterial flora is also an important consideration, as these organisms produce antimicrobial factors which play a role in defense of the ocular tissues from infection (10,14).…”

mentioning

confidence: 99%

Microbial flora in eyes of current and former contact lens wearers

1992

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Microbial flora from the right eye conjunctival sac of 84 consecutively presenting contact lens patients were compared with cultures from both surfaces of their lens after aseptic removal and with the flora of their storage cases. Similar results were obtained from contact lens and conjunctival cultures of each individual; however, there was no correlation between storage case isolates and lens or conjunctival flora, suggesting that in uncomplicated lens wear, the eye is highly efficient in eradicating microorganisms introduced via handling. Conjunctival flora during daily contact lens wear was similar to the conjunctival flora of a matched control group of non-lens wearers. However, bacteria that are considered to be part of the normal ocular flora were isolated significantly more often from former contact lens wearers. The data also indicated that the use of nonperoxide chemical lens disinfection was associated with a higher proportion of positive cultures for pathogenic microorganisms than the use of other forms of disinfection, for both current and former contact lens wearers. The isolation of potential pathogens was particularly common among elderly subjects using thick contact lenses for extended wear. These changes to conjunctival flora may contribute to the increased risk of ocular infection associated with contact lens wear.

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Antibiotic-Producing Bacteria of the Ocular Flora*

Cited by 21 publications

References 13 publications

Bacteriocins of gram-positive bacteria.

Bacteriocins of gram-positive bacteria.

Über die Standortflora der menschlichen Bindehaut: Untersuchungen von 135 Personen unterschiedlichen Alters

Microbial flora in eyes of current and former contact lens wearers

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