ANTIBIOGRAM (Antibiogram)

Akualing, Jeine Stela; Rejeki, Igaa Putri Sri

doi:10.24293/ijcpml.v23i1.1191

Cited by 4 publications

(3 citation statements)

References 9 publications

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“…In hospitals and clinical settings, multidrug-resistant infections lead to prolonged hospitalization, increased rates of morbidity/mortality, and overall healthcare sector costs (Revelas, 2012). Antibiotic susceptibility testing of microorganisms (via antibiograms) should be carried out at least once a year and serve as a basis for updating hospital empiric antibiotic policies (Akualing and Sri Rejeki, 2018).…”

Section: Discussionmentioning

confidence: 99%

Trends in antimicrobial susceptibility patterns of bacterial isolates in Lahore, Pakistan

et al. 2023

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BackgroundAntimicrobial resistance (AMR) has provoked a global health issue. Antimicrobial stewardship programs should be implemented to overcome this issue. The aim of this study was to determine the sensitivity patterns of the WHO Access, Watch, Reserve (AWaRe) group of antibiotics that assists in the selection of appropriate empiric antibiotic therapies.MethodA descriptive, cross-sectional study was conducted for 6 months, in which 422 culture sensitivity sample reports from the Ghurki Trust Teaching Hospital’s laboratory were obtained through a convenience sampling technique, and the sensitivity patterns of nine offending bacteria to the WHO AWaRe group antibiotics were determined. Descriptive statistics and differences in frequency distribution among the categorical variables were obtained using the Statistical Package for Social Sciences (SPSS) software, version 21.ResultsAmong 422 culture sensitivity sample reports, Escherichia coli (16.1%) was the most common Gram-negative pathogen. Acinetobacter, E. coli, Klebsiella, and Pseudomonas showed 100% sensitivity to polymyxin-b and colistin. Proteus showed the highest sensitivity to meropenem (90%), Staphylococcus aureus showed a 98% sensitivity to linezolid, Staphylococcus epidermidis was 100% sensitive to vancomycin and linezolid, and Streptococcus showed the highest sensitivity to penicillin (100%) and vancomycin (94.7%). Polymyxin b and colistin were found to be the most effective antibiotics against Gram-negative bacteria (100%). Gram-positive bacteria were highly sensitive to linezolid (99.4%), vancomycin (98.2%), chloramphenicol (89.5%), and tigecycline (82.6%).ConclusionCulture sensitivity reports help to rationalize the empirical use of antibiotics in clinical practice in addressing the challenge of antimicrobial resistance. This study showed that polymyxin-b and colistin were the most effective antibiotics against Gram-negative isolates and that Gram-positive bacteria were highly susceptible to linezolid. Updated antibiograms should be used by clinicians to evaluate bacterial susceptibility patterns and rationalize antibiotic empiric therapy.

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Section: Discussionmentioning

confidence: 99%

Trends in antimicrobial susceptibility patterns of bacterial isolates in Lahore, Pakistan

et al. 2023

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“…This report shows the alarming spread of antibiotic resistance worldwide [3]. A research conducted in Indonesia showed that of 781 patients in the hospital, 81% of them had resistance with ampicillin, 73% resistance with cotrimoxazole and 56% resist against Escherichia coli [4]. This study was supported by research conducted by Huda in 2016, it was confirmed that Escherichia coli was the most resistant to Sulfamethoxazole (100%), Ampicillin (93.3%) and Cefadroxil (90.9%) [5] and another study conducted by Kibret in 2011 at northeast Ethiopia found that high levels of resistance to erythromycin (89.4%), amoxicillin (86.0%) [6].…”

Section: Introductionmentioning

confidence: 88%

A Survey of Community Perceptions and Knowledge Toward Antibiotic Resistance: Case Study in Magelang, Indonesia

Arfianto,

Hadi Sulistyaningrum,

Pribadi

et al. 2023

BIO Web Conf.

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One of the main causes of antibiotic resistance is the unprescription dispensing of antibiotics, which can result in the improper use of antibiotics. The purpose of a self-administered questionnaire-based study was to gauge participants’ understanding and opinions regarding antibiotic resistance. In October 2019, a cross-sectional descriptive survey was self-administered to individuals. For this survey, Total of 455 respondents were used. Respondents who were residing in Magelang, spoke Indonesian, and were older than eighteen were the inclusion criteria. Six sections made up the questionnaire: demographic information; five questions about general antibiotic resistance information; five questions about the advantages of antibiotics; three questions about prescription antibiotics; four questions about using antibiotics personally; and five questions about antibiotic knowledge. Data analysis were used SPSS version 21, research data is treated as a descriptive analysis. The results show that majority of respondents have the perception that antibiotics are the best choice for treating fever (26.5%), 72.3% of participants are aware of antibiotic resistance. Furthermore, 53.8% of respondents said they completely trusted medical experts’ advice. Health professionals have a greater responsibility to alert the public about antibiotic use and resistance. In conclusion, it is important to increase knowledge about antibiotic resistance because it concerns the general public’s opinion regarding antibiotic resistance and their level of awareness of the risks associated with it. Ultimately, this can change people’s attitudes and actions to use antibiotics wisely.

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“…Similarly, the percentage of resistance was obtained by dividing ∑R by n. The more isolates tested (the more n), the more accurate the percent sensitivity and the percent resistance. Percent sensitivity on the antibiogram is color-coded and numbered if the number is close to 100 or even 100, the antibiotic is sensitive and recommended for further treatment (Akualing & Rejeki, 2018).…”

Section: Methodsmentioning

confidence: 99%

Postoperative Orthopedic Surgical Site Infection Antibiogram of dr. Soebandi Hospital, Jember in 2019

Saffanah

Agustina

Sutejo

2020

J. Pharm. Sci. Clin. Res.

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Surgical site infection (SSI) is a microbial infection of the surgical wound within 30 days of operation or one year after surgery if an implant is placed in a patient. The incidence level of postoperative orthopedic SSI range to 71%. An increase in antibiotic-resistant bacteria causes the treatment of postoperative orthopedic surgical wound infections to be less effective, so there is an increase in morbidity, mortality, length of stay, and economic burden on hospital resources.Antibiogram were used to guidethe clinician and pharmacist selectedthe best empiric antimicrobial treatment in the event of pending microbiology culture and susceptibility results to overcome the disadvantages of antibotic-resistant bacteria. This study aimed to form a postoperative orthopedic SSI antibiogram of dr. Soebandi Hospital in Jember City, East Java, Indonesia which can be used as a reference to rational therapy. This study used a descriptive observational study research design with medical records from January – December 2019.A total of 34 isolates were found from 33 patients who did a culture examination. Of the 34 isolates, 25 were found to be positive for bacterial growth, while nine were negative. Twenty-two bacteria were Gram-negative and others were Gram-positive. The bacteria were tested against beta-lactam and non-beta lactam antibiotics.From antibiogram, showed that Gram-negative bacteria sensitive to the meropenem and resistant to cefotaxime. While, gram-positive bacteria showed sensitivity to doxycycline and resistant to erythromycin and penicillin.

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ANTIBIOGRAM (Antibiogram)

Cited by 4 publications

References 9 publications

Trends in antimicrobial susceptibility patterns of bacterial isolates in Lahore, Pakistan

Trends in antimicrobial susceptibility patterns of bacterial isolates in Lahore, Pakistan

A Survey of Community Perceptions and Knowledge Toward Antibiotic Resistance: Case Study in Magelang, Indonesia

Postoperative Orthopedic Surgical Site Infection Antibiogram of dr. Soebandi Hospital, Jember in 2019

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