Antibacterial Synergistic Activity of Ofloxacin and Ornidazole Treated Biomedical Fabrics against Nosocomial Pathogens

Elayarajah, B; Rajendran, R.; Chandrasekaran, Balakumar; Venkatraja, B.; Sudhakar, Asa; Janiga, PK

doi:10.3923/ajt.2011.87.97

Cited by 7 publications

(3 citation statements)

References 17 publications

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“…Herbal clothing is believed to help restore the balance within the body's systems and strengthen the immune system. Some of the medi-herbs used in herbal textiles give the magical healing quality to the dyed fabric or yarn (Table 1) [12][13][14][15]. Table 1 shows the diseases cured by different herbs.…”

Section: Herbs and Healing Effects Of Herbal Textilementioning

confidence: 99%

Application of Natural Dyes for Herbal Textiles

Mishra¹,

Gautam²

2020

Chemistry and Technology of Natural and Synthetic Dyes and Pigments

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Clothing, the second skin of our body, is of immense importance in human life and has been evolved continuously. Textile products having special properties are used for umpteen purposes, and one such product is herbal textiles. Changing trends in clothing, cosmetics, and aesthetics necessitates the development of newer technologies that can benefit end users by enhancing their health and aesthetics and provide a sense of relief and satisfaction. Herbal textiles are prepared by imparting essential oils and herbal extract finishes to textiles. These treatments provide medicinal value and aroma to the garment, which enhance its value. Herbal extracts and oils can be incorporated in textiles by microencapsulation, sensory perception technology, liposomes, dyes, and coated textile technology. The temperatures of the finish, the duration and concentration of plant extract, the blend of herbs, and the equipment used need to be carefully controlled. Herbal textiles are revitalizing and help in keeping the body fresh and healthy. These fabrics also shown to have therapeutic value in ailments like skin allergies, breathing problems, sleeping disorders, and blood pressure. In this chapter, emphasis is given on the significance of herbal clothing and the use of natural herbal extracts to produce them.

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Section: Herbs and Healing Effects Of Herbal Textilementioning

confidence: 99%

Application of Natural Dyes for Herbal Textiles

Mishra¹,

Gautam²

2020

Chemistry and Technology of Natural and Synthetic Dyes and Pigments

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“…Moxi loxacin and metronidazole were used as antibacterial coating agents on the urinary catheters using a standard slurry-dipping technique (Boccaccini et al, 2003). The coating method and the synergism between the two drugs were described in a previous study (Elayarajah et al, 2011). All the coated materials are designated as UC M M (Moxi loxacin and metronidazole coated Urinary catheter) in the following parameters.…”

Section: Preparation Of Antibacterial Coatings On the Urinary Cathetersmentioning

confidence: 99%

Biofilm Expressing Genes in Bacteria Causing Urinary Catheter Associated Infections

B¹,

S²

2020

ijrps

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Biofilm associated infection causes higher mortality in catheterized patients. Identification of cupA gene in Pseudomonas aeruginosa coding for biofilm formation was selected as a primary objective. Synergistic antibacterial drugs (moxifloxacin-metronidazole) were prepared using the selected concentrations for coatings onto urinary catheter samples. Antibacterial coatings of synergistic antibacterial drugs onto a urinary catheter and its antibacterial activity were evaluated using the standard diffusion method. The drug coated catheters were investigated for their biocompatible properties. The biocompatibility of the drug coated samples was investigated on L929 fibroblast cell lines using MTT assay. The biofilm expressing genes (cupA gene) of the selected organism was detected using molecular methods. During the analysis, the cupA gene from the target organism was confirmed by the PCR method aided with the DNA electrophoresis process. The study was confirmed from the obtained DNA fragments of 172bp by comparing with 170bp fragment of reference bacterial strain. Quantitative antibacterial activity results showed that the drug coated catheter samples were significantly reduced the bacterial numbers. Biocompatibility of coated catheter samples evaluated by in-vitro cell culture cytotoxicity assay exhibited no effect on cell viability of fibroblast cell lines. It is concluded that identifying biofilm expressing genes could help the health care workers to diagnose and treat the patients with an appropriate antibacterial agent.

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“…Nutrient broth (100 mL) was prepared, and the samples named UC, N6C and MN6C were introduced. Then, the cultured S. aureus and E. coli were inoculated in the above nutrient broth followed by incubation at 37℃ for 2 h. After the incubation period, the inoculums from treated broth tubes were inoculated in freshly prepared nutrient agar plates followed by incubation at 37℃ for 24 h and were measured using CFU [23]. Figure 3(b) shows the particle size distribution of the MgO nanoparticles in the range of 22 (d 10 ) to 158 nm (d 90 ) and a mean diameter was about 58 nm (d 50 ).…”

Section: Antibacterial Activitymentioning

confidence: 99%

Electrospun MgO/Nylon 6 Hybrid Nanofibers for Protective Clothing

Rajendran¹,

Dhineshbabu²,

Karunakaran³

et al. 2014

Nano-Micro Lett

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Magnesia (MgO) nanoparticles were produced from magnesite ore (MgCO3) using ball mill. The crystalline size, morphology and specific SSA were characterized by X-ray diffraction analysis, transmission electron microscopy and Brunauer-Emmett-Teller method, respectively. MgO nanoparticle-incorporated nylon 6 solutions were electrospun to produce nanofiber mats. Surface morphology and internal structure of the prepared hybrid nanofiber mats were examined by scanning electron microscopy and high-resolution transmission electron microscopy, respectively. The fire retardancy and antibacterial activity (Staphylococcus aureus and Escherichia coli) of coated fabrics made from MgO/nylon 6 hybrid nanofiber are better than those from nylon 6 nanofiber.

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Antibacterial Synergistic Activity of Ofloxacin and Ornidazole Treated Biomedical Fabrics against Nosocomial Pathogens

Cited by 7 publications

References 17 publications

Application of Natural Dyes for Herbal Textiles

Application of Natural Dyes for Herbal Textiles

Biofilm Expressing Genes in Bacteria Causing Urinary Catheter Associated Infections

Electrospun MgO/Nylon 6 Hybrid Nanofibers for Protective Clothing

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