Antibacterial Management of Urinary Tract Infections

A Clinical Trial with Nalidixic Acid on 22 Acute and Chronic Urinary Tract Infections with Follow-Up for 1–5 Months

“…Our results on the whole are comparable to those of other authors, Barlow (1963), Ward-McQuaid and others (1963), Carroll (1963), Garrod, Shooter and Curwen (1964), Kass (1955), Rhoads, Billings andO'Conor (1952), Turck, Browder, Lindemeyer, Brown, Anderson andPetersdorf (1962). The cure rate in acute infections, that is 7/8, is similar to that obtained by Barlow (1963), Ward-McQuaid and others (1963) and Carroll (1963).…”

A Comparative Study of the Levels of Nalidixic Acid in Plasma and Urine and its Antibacterial Activity in Urinary Infections of Paraplegics

“…56% was better than those published by other authors on chronic urinary infections, Rhoads, Billings and O'Conor (1952); Garrod, Shooter and Curwen (1954); Kass (1955);and Turck, Browder, Lindemeyer, Brown, Anderson and Petersdorf (1962). Our results were as good as those reported by Ward-McQuaid and others (1963) but the cure rate in Barlow's series (1963) was better than ours.…”

Problems in the Aetiology, Diagnosis and Treatment of Pyelonephritis

“…On the other hand, once pyelonephritis is well established, the particular antibiotic used and the duration of treatment seem to have little effect in influencing the ultimate prognosis for the patient, or in reducing the number of episodes of clinically apparent relapses, providing follow‐up studies are sufficiently prolonged. It appears that a complete cure is obtained only in a small proportion of cases with a history of recurrent or chronic infection, especially when there is an abnormality of the urinary tract (Rhoads, Billings and O'Connor 1952).…”