A Comparative Study of the Levels of Nalidixic Acid in Plasma and Urine and its Antibacterial Activity in Urinary Infections of Paraplegics

A Clinical Trial with Nalidixic Acid on 22 Acute and Chronic Urinary Tract Infections with Follow-Up for 1–5 Months

“…The chemistry, pharmacology and toxicology have been detailed elsewhere, Lishman and Swinney (1963) and Ward-McQuaid, Jichlinski and Macis (1963). In a number of clinical trials published recently this chemotherapeutic agent was shown to be very effective against Gram-negative organisms in urinary tract infec-tions, Lishman and Swinney (1963), Jameson and Swinney (1963), Slade (1963), Barlow (1963), Ward-McQuaid and colleagues (1963), Thompson and Rae (1964), McCabe (1963), Carroll (1963) and Gibbon, Benstead and Misra (1965).…”